Abstract: A coupler for aseptically coupling and controlling fluid communication between at least two components. The coupler includes a first connector housing with an inner concave surface. A first connector extends from the top of the first connector housing and is adapted to connect to a first component. A first connector conduit extends through the first connector and into the first connector housing so as to define a fluid passageway to an inner opening on the inner surface of the first connector housing. A rotary valve is located within an inner cavity of the first connector housing and includes at least two rotary valve segments. The rotary valve segments are configured to rotate within the cavity. At least one of the rotary valve segments includes a fluid conduit extending through the at least one rotary valve segment.

Abstract: An aseptic closure system for attaching to a container including an upper section and a lower section that are removably attached to one another. Each section includes a valve housing with a rotary valve mounted in a bore extending through the valve housing. The upper section has an inlet port and an outlet port, each with a conduit providing fluid communication through the port to an interior of the upper valve housing. The lower section is adapted to mount to a container. The lower valve housing includes two conduits that permit fluid communication through the lower valve housing to an interior of the lower section. The rotation of the rotary valves closes off flow through the conduits in the respective housings.

Abstract: An adjustable volume sampling system is disclosed for aseptically retrieving a sample volume of a fluid from an origination container. The system includes a sampling container. A cap is removably attached to the sampling container so as to close off the open top. The cap includes two ports. A first tube is attached to one of the ports. An elongated diptube extends through port into the sampling container and an upper end of the diptube is located inside a portion of the first tube. The diptube can be raised and lowered relative to the sampling container by pinching an stretching the first tube. Syringes are provided for expelling excess material from the sampling container.