Abstract: A process is provided for the preparation of mandelic acid derivatives. The process comprises the steps of: (a) stereoselectively cyanating a compound of Formula (2) to yield the corresponding cyanohydrin; (b) hydrolyzing the product of step (a) to the corresponding compound of Formula (1). wherein X is a substituent.
Type:
Grant
Filed:
February 15, 2002
Date of Patent:
April 4, 2006
Assignee:
Avecia Ltd.
Inventors:
Andrew John Blacker, Ian Nicholas Houson