Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Type:
Application
Filed:
December 30, 2004
Publication date:
February 8, 2007
Applicant:
Aventis Pasteur Ltd
Inventors:
Lynn Doucette-Stamm, David Bush, Qiandong Zeng, Timothy Opperman, Chad Houseweart
Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Type:
Application
Filed:
December 30, 2004
Publication date:
January 11, 2007
Applicant:
Aventis Pasteur Ltd.
Inventors:
Lynn Doucette-Stamm, David Bush, Qiandong Zeng, Timothy Opperman, Chad Houseweart
Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Type:
Application
Filed:
December 30, 2004
Publication date:
January 11, 2007
Applicant:
Aventis Pasteur Ltd
Inventors:
Lynn Doucette-Stamm, David Bush, Qiandong Zeng, Timothy Opperman, Chad Houseweart
Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Type:
Application
Filed:
December 30, 2004
Publication date:
January 11, 2007
Applicant:
Aventis Pasteur Ltd
Inventors:
Lynn Doucette-Stamm, David Bush, Qiandong Zeng, Timothy Opperman, Chad Houseweart
Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Type:
Application
Filed:
December 30, 2004
Publication date:
January 11, 2007
Applicant:
Aventis Pasteur Ltd
Inventors:
Lynn Doucette-Stamm, David Bush, Qiandong Zeng, Timothy Opperman, Chad Houseweart
Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Type:
Application
Filed:
December 30, 2004
Publication date:
January 11, 2007
Applicant:
Aventis Pasteur Ltd
Inventors:
Lynn Doucette-Stamm, David Bush, Qiandong Zeng, Timothy Opperman, Chad Houseweart
Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Type:
Application
Filed:
December 30, 2004
Publication date:
January 11, 2007
Applicant:
Aventis Pasteur Ltd
Inventors:
Lynn Doucette-Stamm, David Bush, Qiandong Zeng, Timothy Opperman, Chad Houseweart
Abstract: The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.
Type:
Application
Filed:
December 30, 2004
Publication date:
January 11, 2007
Applicant:
Aventis Pasteur Ltd.
Inventors:
Lynn Doucette-Stamm, David Bush, Qiandong Zeng, Timothy Opperman, Chad Houseweart
Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. In particular, the invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer.
Type:
Application
Filed:
April 15, 2004
Publication date:
May 26, 2005
Applicant:
Aventis Pasteur, Ltd.
Inventors:
Neil Berinstein, Scott Gallichan, Corey Lovitt, Mark Parrington, Artur Pedyczak, Laszlo Radvanyi, Devender Singh-Sandhu
Abstract: The present invention relates to the field of cancer immunotherapy. In particular, vaccines are administered in conjunction with high doses of cytokines to enhance an anti-tumor immune response.
Type:
Application
Filed:
October 21, 2003
Publication date:
November 11, 2004
Applicant:
Sunnybrook and Women's College Health Sciences Center Aventis Pasteur, Ltd.
Inventors:
Igor Astsaturov, Teresa Petrella, Mark DeBenedette, Neil Berinstein, David E. Spaner
Abstract: The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. In particular, the invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer.
Type:
Application
Filed:
July 1, 2003
Publication date:
October 7, 2004
Applicant:
Aventis Pasteur, Ltd.
Inventors:
Neil Berinstein, Corey Lovitt, Mark Parrington, Artur Pedyczak, Laszlo Radvanyi, Scott Gallichan, Devender Singh-Sandhu, Raymond P. Oomen, Shi-Xian Cao
Abstract: The present invention provides reagents and methods for producing and utilizing targeted immunogens. In preferred embodiments, an immunogen is conjugated to an amino acid sequence that targets the immunogen to the MHC presentation pathway. Using the reagents and methods provided herein, immunization protocols may be enhanced resulting in increased immunity of the host.
Type:
Application
Filed:
January 29, 2003
Publication date:
January 1, 2004
Applicants:
Aventis Pasteur, Ltd., Aventis Pharmaceuticals, Inc.
Inventors:
Robert Adam Uger, Danielle Salha, Brian Barber, Clarence C. Morse, Yong Guo, Su Cheng
Abstract: The present invention relates to peptides, polypeptides, and nucleic acids and the use of the peptide, polypeptide or nucleic acid in preventing and/or treating cancer. In particular, the invention relates to peptides and nucleic acid sequences encoding such peptides for use in diagnosing, treating, or preventing melanoma.
Type:
Application
Filed:
August 15, 2002
Publication date:
June 19, 2003
Applicant:
Aventis Pasteur, Ltd.
Inventors:
Peter Emtage, Liza Karunakaran, Artur Pedyczak, Brian Barber