Abstract: A compound of the formula wherein R is defined as in the specification, which compounds have an inhibitory effect vis-à-vis cycline-dependent kinase proteins (cdk) and are endowed with antimitotic properties.
Abstract: A series of aryl-heteroaromatic compounds, compositions comprising them and use thereof are disclosed and claimed. The present invention relates in particular to novel aryl-heteroaromatic compounds exhibiting anticancer activity, and in particular inhibitory activity with regard to tubulin polymerization.
Type:
Application
Filed:
July 23, 2004
Publication date:
January 27, 2005
Applicant:
Aventis Pharma
Inventors:
Patrick Mailliet, Alain Le-Brun, Fabienne Thompson, Gilles Tiraboschi
Abstract: The present invention relates to oligosaccharides of formula:
to mixtures thereof, to diastereoisomers thereof, to a process for preparing them, to pharmaceutical compositions containing them, and to their use in preventing or treating a disease associated with an inflammatory process involving the production of nitric oxide.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
September 9, 2003
Assignee:
Aventis Pharma
Inventors:
Pierre Mourier, Elisabeth Perrin, Jean-marie Stutzmann, Christian Viskov, Florence Wahl