Patents Assigned to Aventis Pharmaceuticals Holdings Inc.
  • Patent number: 7731758
    Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: June 8, 2010
    Assignee: Aventis Pharmaceuticals Holdings, Inc.
    Inventors: Jérôme Asius, Hatem Fessi, Franck Gouchet, Bénedicte Laglenne, Elisabeth Laugier-Laglenne
  • Patent number: 7122206
    Abstract: An aqueous pharmaceutical composition which is capable of being sprayed into the nasal cavity of an individual and which comprises: (A) a pharmaceutically effective amount of solid particles of medicament which is effective in treating a bodily condition by virtue of its being present on the mucosal surfaces of the nasal cavity; and (B) a suspending agent in an amount effective to maintain said particles dispersed uniformly in the composition and to impart to the composition the following thixotropic properties: (i) the viscosity of the position in unsheared form is relatively high, with the composition being in gel-like form; (ii) as the composition is subjected to shear (shaken) in preparation for spraying, the viscosity of the composition becomes relatively low and such that the composition in the form of a mist flows readily into the nasal passages for deposit on the mucosal surfaces of the nasal cavity; and (D) in deposited form on the mucosal surfaces, the viscosity of the composition is relatively high
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: October 17, 2006
    Assignee: Aventis Pharmaceuticals Holding Inc.
    Inventor: Soo-Il Kim
  • Publication number: 20040191323
    Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.
    Type: Application
    Filed: March 26, 2004
    Publication date: September 30, 2004
    Applicant: Aventis Pharmaceuticals holdings, Inc.
    Inventors: Jerome Asius, Hatem Fessi, Franck Gouchet, Benedicte Laglenne, Elisabeth Laugier-Laglenne
  • Patent number: 6716251
    Abstract: The invention concerns an injection implant for filling up wrinkles, thin lines, skin cracks and scars, for reparative or plastic surgery, aesthetic dermatology, and for filling up gums in dental treatment. The invention concerns the use of biologically absorbable polymer microspheres or microparticles suspended in a gel. Said suspension is produced either ready-for-use or freeze-dried. The biological absorbability of the microspheres is controlled and enables the production of implants having well defined persistence and deliberately limited to 3 years.
    Type: Grant
    Filed: February 8, 1999
    Date of Patent: April 6, 2004
    Assignee: Aventis Pharmaceuticals Holdings, Inc.
    Inventors: Jérôme Asius, Hatem Fessi, Franck Gouchet, Bénédicte Laglenne, Elisabeth Laugier-Laglenne
  • Patent number: 6528292
    Abstract: Molded articles formed of polystyrene or other polymers containing an aromatic moiety can be derivatized on the surface of the article by subjecting the molded article to a chemical reaction wherein the reaction media utilizes tetramethylsulfone as the reactant solvent and a suitable substituent group which is substituted on to the aromatic moiety of the polystyrene or other polymer by electrophilic substitution. By choosing the substituent group to further include a leaving group, further substitution of the primary substituent can be effected normally by nucleophilic substitution reaction. In this way, biologically important molecules can be attached to a polystyrene or other aromatic containing polymer without effecting certain properties of the molded article such as its optical or spectroscopic clarity.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: March 4, 2003
    Assignee: Aventis Pharmaceuticals Holdings Inc.
    Inventor: Brian R. Clark