Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
Type:
Grant
Filed:
September 13, 2005
Date of Patent:
December 18, 2007
Assignees:
Avera Pharmaceuticals, Inc., Eli Lilly and Company
Inventors:
Alexander Glenn Godfrey, Daniel Timothy Kohlman, John Cunningham O'Toole, Yao-Chang Xu, Tony Yantao Zhang, Jeffrey Forrester McKelvy
Abstract: A series of aryl piperazine compounds are effective pharmaceuticals for the treatment of conditions related to or affected by the serotonin 1A receptor; the compounds are particularly effective antagonists at that receptor, and are particularly useful for alleviating the symptoms of nicotine and tobacco withdrawal.
Type:
Grant
Filed:
April 16, 2003
Date of Patent:
February 21, 2006
Assignees:
Avera Pharmaceuticals, Inc., Eli Lilly and Company
Inventors:
Alexander Glenn Godfrey, Daniel Timothy Kohlman, John Cunningham O'Toole, Yao-Chang Xu, Tony Yantao Zhang