Abstract: Systems and methods for polynucleotide synthesis utilize electrochemical deprotection and novel redox chemistries compatible with advanced CMOS nodes, for highly reliable and massively scalable parallel construction of polynucleotide segments having a desired sequence or sequences. Via use of these exemplary techniques, low-cost and large-scale polynucleotide synthesis is facilitated, for example for data storage and retrieval applications.
Type:
Grant
Filed:
April 13, 2022
Date of Patent:
August 15, 2023
Assignee:
Avery Digital Data, Inc.
Inventors:
Barry Merriman, Ryan de Ridder, Matthew T. Holden, Tim Geiser
Abstract: Systems and methods for polynucleotide synthesis utilize electrochemical deprotection and novel redox chemistries compatible with advanced CMOS nodes, for highly reliable and massively scalable parallel construction of polynucleotide segments having a desired sequence or sequences. Via use of these exemplary techniques, low-cost and large-scale polynucleotide synthesis is facilitated, for example for data storage and retrieval applications.
Type:
Application
Filed:
April 13, 2022
Publication date:
September 8, 2022
Applicant:
Avery Digital Data, Inc.
Inventors:
Barry Merriman, Ryan de Ridder, Matthew T. Holden, Tim Geiser