Patents Assigned to Avexa Limited
  • Bicyclic pyrimidinones and uses thereof
    Patent number: 8859563
    Abstract: The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. A pharmaceutical composition or medicament comprising a compound of Formula I is also provided.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: October 14, 2014
    Assignee: Avexa Limited
    Inventors: Eric Dale Jones, Jonathan Alan Victor Coates, David Ian Rhodes, John Joseph Deadman, Nicholas Andrew Van de Graff, Lisa Jane Winfield, Neeranat Thienthong, William Issa, Neil Choi, Katherine Macfarlane
  • Compounds having antiviral properties
    Patent number: 8563562
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: October 22, 2013
    Assignee: Avexa Limited
    Inventors: John Joseph Deadman, Eric Dale Jones, Giang Thanh Le, David Ian Rhodes, Neeranat Theinthong, Nicholas Andrew Van de Graff, Lisa Jane Winfield
  • NOVEL ANTIVIRAL AGENTS
    Publication number: 20130178469
    Abstract: The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof.
    Type: Application
    Filed: July 15, 2011
    Publication date: July 11, 2013
    Applicants: SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY (SIOC), AVEXA LIMITED
    Inventors: David Ian Rhodes, John Joseph Deadman, Giang Thanh Le, Nicholas Andrew Van de Graff, Lu Long, Li Xinming, Feng Xiao, Yu Changjiang
  • Imidazopyrimidines and uses thereof
    Patent number: 8431581
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: April 30, 2013
    Assignee: Avexa Limited
    Inventors: John Joseph Deadman, Eric Dale Jones, Giang Thanh Le, David Ian Rhodes, Neeranat Thienthong, Nicholas Andrew Van de Graff, Lisa Jane Winfield
  • Thiazopyrimidinones and uses thereof
    Patent number: 8426405
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof are disclosed. Also disclosed are methods of treating a viral infection in a subject by administering to the subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: April 23, 2013
    Assignee: Avexa Limited
    Inventors: John Joseph Deadman, Eric Dale Jones, Giang Thanh Le, David Ian Rhodes, Neeranat Thienthong, Nicholas Andrew Vandegraaff, Lisa Jane Winfield
  • COMPOUNDS HAVING ANTIVIRAL PROPERTIES
    Publication number: 20130059865
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.
    Type: Application
    Filed: September 13, 2012
    Publication date: March 7, 2013
    Applicant: AVEXA LIMITED
    Inventors: John Joseph Deadman, Eric Dale Jones, Giang Thanh Le, David Ian Rhodes, Neeranat Theinthong, Nicholas Andrew Van de Graff, Lisa Jane Winfield
  • Compounds having antiviral properties
    Patent number: 8318732
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: November 27, 2012
    Assignee: Avexa Limited
    Inventors: John Joseph Deadman, Eric Dale Jones, David Ian Rhodes, Nicholas Andrew Van de Graff
  • Process for chiral resolution of 2-substituted 4-substituted 1,3-oxathiolanes
    Patent number: 8318934
    Abstract: The present invention relates to a novel process for the chiral resolution of 2-substituted 4-substituted 1,3-oxathiolanes and derivatives thereof. The present invention also relates to novel 2-substituted 4-substituted 1,3-oxathiolanes derivatives.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: November 27, 2012
    Assignee: Avexa Limited
    Inventors: Widanagamage Ruwansiri Epa, Sebastian Mario Marcuccio, John Joseph Deadman
  • Bicyclic pyrimidinones and uses thereof
    Publication number: 20120232035
    Abstract: The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. A pharmaceutical composition or medicament comprising a compound of Formula I is also provided.
    Type: Application
    Filed: February 27, 2012
    Publication date: September 13, 2012
    Applicant: AVEXA LIMITED
    Inventors: Eric Dale Jones, Jonathan Alan Victor Coates, David Ian Rhodes, John Joseph Deadman, Nicholas Andrew Vandegraff, Lisa Jane Winfield, Neeranat Thienthong, William Issa, Neil Choi, Katherine Macfarlane
  • Bicyclic pyrimidinones and uses thereof
    Patent number: 8207334
    Abstract: The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. A pharmaceutical composition or medicament comprising a compound of Formula I is also provided.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: June 26, 2012
    Assignee: Avexa Limited
    Inventors: Eric Dale Jones, Jonathan Alan Victor Coates, David Ian Rhodes, John Joseph Deadman, Nicholas Andrew Vandegraff, Lisa Jane Winfield, Neeranat Thienthong, William Issa, Neil Choi, Katherinie Macfarlane
  • Bicyclic pyrimidinones and uses thereof
    Patent number: 8143268
    Abstract: The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. A pharmaceutical composition or medicament comprising a compound of Formula I is also provided.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: March 27, 2012
    Assignee: Avexa Limited
    Inventors: Eric Dale Jones, Jonathan Alan Victor Coates, David Ian Rhodes, John Joseph Deadman, Nicholas Andrew Vandegraff, Lisa Jane Winfield, Neeranat Thienthong, William Issa, Neil Choi, Katherine Macfarlane
  • IMIDAZOPYRIMIDINES AND USES THEREOF
    Publication number: 20110028487
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.
    Type: Application
    Filed: July 2, 2009
    Publication date: February 3, 2011
    Applicant: AVEXA LIMITED
    Inventors: John Joseph Deadman, Eric Dale Jones, Giang Thanh Le, David Ian Rhodes, Neeranat Thienthong, Nicholas Andrew Van De Graff, Lisa Jane Winfield
  • BICYCLIC PYRIMIDINONES AND USES THEREOF
    Publication number: 20110009366
    Abstract: The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. A pharmaceutical composition or medicament comprising a compound of Formula I is also provided.
    Type: Application
    Filed: April 23, 2010
    Publication date: January 13, 2011
    Applicant: AVEXA LIMITED
    Inventors: Eric Dale Jones, Jonathan Alan Victor Coates, David Ian Rhodes, John Joseph Deadman, Nicholas Andrew Vandegraff, Lisa Jane Winfield, Neeranat Thienthong, William Issa, Neil Choi, Katherinie Macfarlane
  • PROCESS FOR CHIRAL RESOLUTION OF 2-SUBSTITUTED 4-SUBSTITUTED 1,3-OXATHIOLANES
    Publication number: 20100305321
    Abstract: The present invention relates to a novel process for the chiral resolution of 2-substituted 4-substituted 1,3-oxathiolanes and derivatives thereof. The present invention also relates to novel 2-substituted 4-substituted 1,3-oxathiolanes derivatives.
    Type: Application
    Filed: September 26, 2008
    Publication date: December 2, 2010
    Applicant: AVEXA LIMITED
    Inventors: Widanagamage Ruwansiri Epa, Sebastian Mario Marcuccio, John Joseph Deadman
  • BICYCLIC PYRIMIDINONES AND USES THEREOF
    Publication number: 20100168063
    Abstract: The present invention provides a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. Further provided is a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of Formula I or a pharmaceutically acceptable derivative, salt or prodrug thereof. A pharmaceutical composition or medicament comprising a compound of Formula I is also provided.
    Type: Application
    Filed: December 21, 2007
    Publication date: July 1, 2010
    Applicant: Avexa Limited
    Inventors: Eric Dale Jones, Jonathan Alan Coates, David Ian Rhodes, John Joseph Deadman, Nicholas Andrew Vandegraff, Lisa Jane Winfield, Neeranat Thienthong, William Issa, Neil Choi, Katherine MacFarlane
  • Integrase Inhibitors 3
    Publication number: 20100009973
    Abstract: The present invention provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Compounds of formula (I) are also provided.
    Type: Application
    Filed: April 30, 2007
    Publication date: January 14, 2010
    Applicant: AVEXA LIMITED
    Inventors: David Ian Rhodes, Katherine MacFarlane, Eric Dale Jones, William Issa, John Joseph Deadman, Neil Choi