Abstract: Collagen, such as, corium, is freed of pyrogenetic substances by processing green corium with aqueous solutions of alkalie or alkaline earth metal hypochlorites, washing with aqueous ethanol and subsequently washing with pyrogen free water.

Abstract: A fluffy, finely-divided fibrous collagen derived product having hemostatic and adhesive properties sufficient to join together severed biological surfaces in a live warm blooded animal when the product is wet with blood between the surfaces. In the preparation of the product, water-wet collagen is treated with ethanol to remove water, is converted to a ionizable partial salt in the presence of ethanol and dehydrated with ethanol so as to control and limit the swelling of the collagen fibers and prevent hornification upon drying. The recovered dry material is subjected to deaggregation to form a mass having a bulk density of not more than 8 pounds per cubic foot and a surface area of at least 1 square meter per gram.

Abstract: Regenerated cellulose sponges of incresed absorbency and rate of absorption formed by impregnating the sponge material with a solution or dispersion containing from 0.005 to 0.25% of a water-soluble or water-dispersible, high molecular weight, hydrophylic, film-forming polymer, drying the impregnated sponge and compressing it. The presence of the film-forming polymer allows the cutting of desired shaped individual sponges from the treated sponge material with a minimal formation of lint particles on the cut surfaces.

Abstract: Non-woven, liquid-laid, fibrous web having hemostatic and adhesive properties adapted to seal a wound formed of fibers consisting of an ionizable, water-insoluble, partial salt of collagen, the web when placed on a saline solution disintegrating completely and the fibers self disperse. The web is formed from a slurry of the fibers in a water-miscible organic liquid such as ethanol containing a small proportion of an ionizable acid.

Abstract: Regenerated cellulose sponges of increased absorbency and rate of absorption formed by impregnating the sponge material with a solution or dispersion containing from 0.005% to 0.25% of a water-soluble or water-dispersible, high molecular weight, hydrophylic, film-forming polymer, drying the impregnated sponge and compressing it. The presence of the film-forming polymer allows the cutting of desired shaped individual sponges from the treated sponge material with a minimal formation of lint particles on the cut surfaces.