Patents Assigned to Avicore Biotechnology Institute Inc.
  • Method for culturing avian spermatogonial stem cells and avian spermatogonial stem cells prepared thereby
    Patent number: 7754479
    Abstract: The present invention relates to a method for long-term culturing of avian spermatogonial stem cells, which comprises the steps of: (a) preparing an avian testis; (b) isolating a population of testicular cells from said avian testis; and (c) culturing said avian spermatogonial stem cells in said population of testicular cells on a feeder cell layer in a medium containing a cell growth factor, a population of avian spermatogonial stem cells and a method for producing transgenic ayes.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: July 13, 2010
    Assignees: Seoul National University Industry Foundation, Avicore Biotechnology Institute Inc.
    Inventors: Jae Yong Han, Yeong Ho Hong, Jeong Mook Lim, Young Mok Lee, Mak Soon Lee, Jin Gyung Jung
  • Method for improving germline transmission efficiency of avian primordial germ cells
    Patent number: 7476776
    Abstract: The present invention relates to a method for improving the germline transmission efficiency of avian primordial germ cells (PGCs), and methods for producing avian chimeras and transgenic using it. The present method comprises the steps of (a) isolating primordial germ cells (PGCs) from an avian embryonic gonad; and (b) culturing said PGCs in vitro for at least 5 days. According to the present method, the germline transmission efficiency of PGCs can be dramatically improved in a feasible manner.
    Type: Grant
    Filed: April 21, 2004
    Date of Patent: January 13, 2009
    Assignees: Seoul National University Industry Foundation, Avicore Biotechnology Institute Inc., Hanmi Pharm. Co. Ltd.
    Inventors: Jae Yong Han, Tae Sub Park, Yeong Ho Hong, Se Chang Kwon
  • Method for identifying a testicular cell of a chicken
    Patent number: 7427481
    Abstract: The present invention relates to a nucleotide sequence of a testis-specific gene in avian species and a method for identifying a testicular cell of avian species.
    Type: Grant
    Filed: August 26, 2005
    Date of Patent: September 23, 2008
    Assignee: Avicore Biotechnology Institute Inc.
    Inventors: Ji Hye Shin, Beom Ku Han, Heebal Kim, Jae Yong Han
  • Method for producing avian chimera using spermatogonial cells and avian chimera
    Publication number: 20070044167
    Abstract: The present invention relates to a method for producing an avian chimera using spermatogonial cells which comprising the steps: (a) retrieving a testis from a donor ave; (b) isolating a testicular cell population from the testis; (c) culturing the testicular cell population in a medium supplemented with a cell growth factor to obtain a spermatogonial cell population; and (d) injecting the cultured spermatogonial cell population or testicular cell population into a testis of a recipient ave to produce the avian chimera. In addition, the present invention relates to a germline avian chimera.
    Type: Application
    Filed: August 11, 2004
    Publication date: February 22, 2007
    Applicants: Avicore Biotechnology Institute Inc., Seoul National University Industry Foundation
    Inventors: Jae Han, Jeong Mook Lim, Young Lee, Jin Nam Kim, Yeong Hong, Beom Han
  • Recombinant scFV antibodies specific to Eimeria spp. responsible for coccidiosis
    Patent number: 6790937
    Abstract: The present invention relates to (a) variable regions of heavy and light chains of an antibody specific to a surface antigen in sporozoite of Eimeria spp.; (b) a recombinant scFV (single chain variable fragment) antibody prepared using the variable regions; (c) a method for preparing a recombinant scFv antibody; and (d) an expression vector for expressing a recombinant scFv antibody.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: September 14, 2004
    Assignee: Avicore Biotechnology Institute Inc.
    Inventors: Jin-Kyoo Kim, Jae-Yong Han, Ki-Duck Song, Sung-Won Kim, Won-Gi Min, Eun-Jung Son, Hyun Soon Lillehoj, Erik Peter Lillehoj