Patents Assigned to Avidia Research Institute
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Publication number: 20060286603Abstract: Methods for identifying discrete monomer domains and immuno-domains with a desired property are provided. Methods for generating multimers from two or more selected discrete monomer domains are also provided, along with methods for identifying multimers possessing a desired property. Presentation systems are also provided which present the discrete monomer and/or immuno-domains, selected monomer and/or immuno-domains, multimers and/or selected multimers to allow their selection. Compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: March 28, 2006Publication date: December 21, 2006Applicant: Avidia Research InstituteInventors: Joost Kolkman, Willem Stemmer, Per-Ola Freskgard
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Publication number: 20060234299Abstract: Specific monomer domains and multimers comprising the monomer domains are provided. Methods, compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: November 16, 2005Publication date: October 19, 2006Applicant: Avidia Research InstituteInventors: Willem Stemmer, Martin Vogt, Joost Kolkman, Josh Silverman, Candace Swimmer
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Publication number: 20060223114Abstract: The present invention provides thrombospondin, thyroglobulin and trfoil/PD monomer domains and multimers comprising the monomer domains are provided. Methods, compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: November 16, 2005Publication date: October 5, 2006Applicant: Avidia Research InstituteInventors: Willem Stemmer, Martin Vogt, Joost Kolkman, Josh Silverman
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Publication number: 20060177831Abstract: Polypeptides comprising monomer domains that bind to c-MET, or portions thereof, are provided.Type: ApplicationFiled: June 17, 2005Publication date: August 10, 2006Applicant: Avidia Research InstituteInventors: Willem Stemmer, D. Perlroth, Sanjeev Satyal, Benjamin Alba, Alice Bakker, Amy Duguay, Qiang Liu, Joshua Silverman, Richard Smith, Candace Swimmer
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Publication number: 20060008844Abstract: Polypeptides comprising monomer domains that bind to c-Met, or portions thereof, are provided.Type: ApplicationFiled: September 30, 2004Publication date: January 12, 2006Applicant: Avidia Research InstituteInventors: Willem Stemmer, D. Victor Perlroth, Sanjeev Satyal
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Publication number: 20050221384Abstract: Methods for identifying discrete monomer domains and immuno-domains with a desired property are provided. Methods for generating multimers from two or more selected discrete monomer domains are also provided, along with methods for identifying multimers possessing a desired property. Presentation systems are also provided which present the discrete monomer and/or immuno-domains, selected monomer and/or immuno-domains, multimers and/or selected multimers to allow their selection. Compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: October 15, 2004Publication date: October 6, 2005Applicants: Avidia Research Institute, Maxygen, Inc.Inventors: Joost Kolkman, Willem Stemmer, Per-Ola Freskgard
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Publication number: 20050164301Abstract: Specific monomer domains and multimers comprising the monomer domains are provided. Methods, compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: October 22, 2004Publication date: July 28, 2005Applicant: Avidia Research InstituteInventors: Joost Kolkman, Willem Stemmer
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Publication number: 20050089932Abstract: Methods for identifying discrete monomer domains and immuno-domains with a desired property are provided. Methods for generating multimers from two or more selected discrete monomer domains are also provided, along with methods for identifying multimers possessing a desired property. Presentation systems are also provided which present the discrete monomer and/or immuno-domains, selected monomer and/or immuno-domains, multimers and/or selected multimers to allow their selection. Compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: June 17, 2004Publication date: April 28, 2005Applicant: Avidia Research InstituteInventors: Joost Kolkman, Willem Stemmer, Per-Ola Freskgard
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Publication number: 20050053973Abstract: Methods for identifying discrete monomer domains and immuno-domains with a desired property are provided. Methods for generating multimers from two or more selected discrete monomer domains are also provided, along with methods for identifying multimers possessing a desired property. Presentation systems are also provided which present the discrete monomer and/or immuno-domains, selected monomer and/or immuno-domains, multimers and/or selected multimers to allow their selection. Compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: May 5, 2004Publication date: March 10, 2005Applicant: Avidia Research InstituteInventors: Joost Kolkman, Willem Stemmer, Per-Ola Freskgard
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Publication number: 20050048512Abstract: Methods for identifying discrete monomer domains and immuno-domains with a desired property are provided. Methods for generating multimers from two or more selected discrete monomer domains are also provided, along with methods for identifying multimers possessing a desired property. Presentation systems are also provided which present the discrete monomer and/or immuno-domains, selected monomer and/or immuno-domains, multimers and/or selected multimers to allow their selection. Compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: October 24, 2003Publication date: March 3, 2005Applicant: Avidia Research InstituteInventors: Joost Kolkman, Willem Stemmer, Per-Ola Freskgard
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Publication number: 20040175756Abstract: Methods for identifying discrete monomer domains and immuno-domains with a desired property are provided. Methods for generating multimers from two or more selected discrete monomer domains are also provided, along with methods for identifying multimers possessing a desired property. Presentation systems are also provided which present the discrete monomer and/or immuno-domains, selected monomer and/or immuno-domains, multimers and/or selected multimers to allow their selection. Compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention.Type: ApplicationFiled: October 24, 2003Publication date: September 9, 2004Applicant: Avidia Research InstituteInventors: Joost A. Kolkman, Willem P.C. Stemmer, Per-Ola Freskgard