Patents Assigned to AVIDITY BIOSCIENCES, INC.
  • Compositions and methods of treating muscle atrophy and myotonic dystrophy
    Patent number: 12263224
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Grant
    Filed: November 17, 2022
    Date of Patent: April 1, 2025
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • Nucleic acid-polypeptide compositions and uses thereof
    Patent number: 12234290
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: February 25, 2025
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Rachel Elizabeth Johns, Palani Balu, Rob Burke, Beatrice Diana Darimont
  • Compositions and methods of treating facioscapulohumeral muscular dystrophy
    Patent number: 12157774
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating facioscapulohumeral muscular dystrophy (FSHD).
    Type: Grant
    Filed: January 2, 2024
    Date of Patent: December 3, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, Beatrice Diana Darimont, David Sala Cano
  • Compositions and methods of treating facioscapulohumeral muscular dystrophy
    Patent number: 12104156
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: October 1, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, David Sala Cano, Beatrice Diana Darimont
  • Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
    Patent number: 12071621
    Abstract: Disclosed herein are antibody oligonucleotide conjugates and pharmaceutical compositions that induce an alteration in an incorrectly spliced dystrophin mRNA transcript to induce exon 44 skipping. Also described herein include methods for treating muscle dystrophy including Duchenne muscular dystrophy that comprises administering antibody oligonucleotide conjugates or a pharmaceutical composition that induces alteration in an incorrectly spliced dystrophin mRNA transcript to induce exon 44 skipping.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: August 27, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Beatrice Diana Darimont, Usue Etxaniz Irigoien, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Isaac Marks, Tyler Albin
  • Compositions and methods of treating facioscapulohumeral muscular dystrophy
    Patent number: 12071485
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating facioscapulohumeral muscular dystrophy (FSHD).
    Type: Grant
    Filed: January 2, 2024
    Date of Patent: August 27, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, Beatrice Diana Darimont, David Sala Cano
  • Nucleic acid-polypeptide compositions and methods of inducing exon skipping
    Patent number: 12064483
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: August 20, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • Compositions and methods of treating Facioscapulohumeral muscular dystrophy
    Patent number: 12049629
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: July 30, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, David Sala Cano, Beatrice Diana Darimont
  • Una amidites and uses thereof
    Patent number: 12006499
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a disease which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: June 11, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Venkata Ramana Doppalapudi, Michael Caramian Cochran
  • Compositions and methods of treating facioscapulohumeral muscular dystrophy
    Patent number: 11999955
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: June 4, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, David Sala Cano, Beatrice Diana Darimont
  • Compositions and methods of treating facioscapulohumeral muscular dystrophy
    Patent number: 11912779
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating facioscapulohumeral muscular dystrophy (FSHD).
    Type: Grant
    Filed: September 15, 2022
    Date of Patent: February 27, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, Beatrice Diana Darimont, David Sala Cano
  • Compositions and methods of treating muscle atrophy and myotonic dystrophy
    Patent number: 11872287
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: January 16, 2024
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • Anti-transferrin receptor antibodies and uses thereof
    Patent number: 11834510
    Abstract: Disclosed herein, in certain embodiments, are anti-transferrin receptor antibodies, anti-transferrin receptor antibody conjugates, and pharmaceutical compositions which comprise the anti-transferrin receptor antibodies or conjugates. In some embodiments, also disclosed herein are methods of delivering a payload utilizing an anti-transferrin receptor antibody described herein, and methods of treatment with use of an anti-transferrin receptor antibody described herein.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: December 5, 2023
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Beatrice Diana Darimont, Venkata Ramana Doppalapudi, Rachel Johns
  • Compositions and methods of treating muscle atrophy and myotonic dystrophy
    Patent number: 11712478
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Grant
    Filed: October 12, 2021
    Date of Patent: August 1, 2023
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • Compositions and methods of treating muscle dystrophy
    Patent number: 11707532
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
    Type: Grant
    Filed: August 8, 2022
    Date of Patent: July 25, 2023
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Venkata Ramana Doppalapudi, Michael David Hood, Rob Burke, Michael Caramian Cochran, Beatrice Diana Darimont, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • Compositions and methods of treating muscle atrophy and myotonic dystrophy
    Patent number: 11576980
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: February 14, 2023
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • Nucleic acid-polypeptide compositions and uses thereof
    Patent number: 11578090
    Abstract: Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer. Also described herein include methods for treating a cancer which utilize a composition or a pharmaceutical formulation comprising a binding moiety conjugated to a polynucleic acid molecule and a polymer.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: February 14, 2023
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Venkata Ramana Doppalapudi, Michael Caramian Cochran, David Sai-Ho Chu, Joel Daniel Arias, Rob Burke
  • Compositions and methods of treating muscle atrophy and myotonic dystrophy
    Patent number: 11554176
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
    Type: Grant
    Filed: September 1, 2021
    Date of Patent: January 17, 2023
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
  • Compositions and methods of treating Facioscapulohumeral muscular dystrophy
    Patent number: 11555190
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: January 17, 2023
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, David Sala Cano, Beatrice Diana Darimont
  • Compositions and methods of treating Facioscapulohumeral muscular dystrophy
    Patent number: 11525137
    Abstract: Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: December 13, 2022
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Barbora Malecova, Rob Burke, David Sala Cano, Beatrice Diana Darimont