Patents Assigned to Avita International Ltd.
  • Patent number: 11306290
    Abstract: The invention provides a method of producing human immature dental pulp stem cells (hIDPSCs) expressing CD44 and CD13 and lacking expression of CD146. The invention also provides compositions for use in the treatment of a neurological disease or condition selected from the group consisting of Parkinson's disease (PD), multiple sclerosis, amyotrophic lateral sclerosis (ALS), stroke, autoimmune encephalomyelitis, diabetic neuropathy, glaucomatous neuropathy, Alzheimer's disease, Huntington's disease (HD), autism, schizophrenia, stroke, ischemia, a motor disorder, and a convulsive disorder.
    Type: Grant
    Filed: September 8, 2018
    Date of Patent: April 19, 2022
    Assignees: AVITA INTERNATIONAL LTD., FUNDAÇÃO BUTANTAN
    Inventors: Irina Kerkis, Cristiane Valverde Wenceslau
  • Patent number: 11278574
    Abstract: The invention provides pharmaceutical compositions comprising human immature dental pulp stem cells (hIDPSCs) wherein the hIDPSCs express CD44 and CD13. The invention also provides methods of treating a neurological disease or condition comprising systemically administering to a subject a pharmaceutical composition comprising hIDPSCs wherein the hIDPSCs express CD44 and CD13. For example, for treating neurological diseases or conditions including supporting the neuro-protective mechanism in subjects diagnosed with early HD or repairing lost DA neurons in subjects diagnosed with PD.
    Type: Grant
    Filed: September 8, 2018
    Date of Patent: March 22, 2022
    Assignees: AVITA INTERNATIONAL LTD., FUNDAÇÂO BUTANTAN
    Inventors: Irina Kerkis, Cristiane Valverde Wenceslau
  • Patent number: 11207352
    Abstract: The invention provides pharmaceutical compositions comprising human immature dental pulp stem cells (hIDPSCs) wherein the hIDPSCs express CD44 and CD13. The invention also provides methods of treating a neurological disease or condition comprising systemically administering to a subject a pharmaceutical composition comprising hIDPSCs wherein the hIDPSCs express CD44 and CD13. For example, for treating neurological diseases or conditions including supporting the neuro-protective mechanism in subjects diagnosed with early HD or repairing lost DA neurons in subjects diagnosed with PD.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: December 28, 2021
    Assignees: AVITA INTERNATIONAL LTD., FUNDAÇÃO BUTANTAN
    Inventors: Irina Kerkis, Alexandre Kerkis
  • Patent number: 9498498
    Abstract: There is a high stem cell therapy potential in the field of reproductive disorders. Endometriosis is a common finding in women with infertility. In addition endometriosis is the major problem in the veterinary field. In the disclosed invention we provide a method of application and use of adipose tissue derived stem cell to treat fertility and pregnancy related disorders, especially endometriosis in mammalian objects.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 22, 2016
    Assignee: Avita International Ltd.
    Inventor: Irina Kerkis
  • Publication number: 20140271572
    Abstract: There is a high stem cell therapy potential in the field of reproductive disorders. Endometriosis is a common finding in women with infertility. In addition endometriosis is the major problem in the veterinary field. In the disclosed invention we provide a method of application and use of adipose tissue derived stem cell to treat fertility and pregnancy related disorders, especially endometriosis in mammalian objects.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Avita International Ltd.
    Inventor: Irina Kerkis