Abstract: The present invention relates to novel genetic markers associated with degenerative disc disease (DDD), risk of developing DDD and risk of DDD progression, and methods and materials for determining whether a human subject has DDD, is at risk of developing DDD or is at risk of DDD progression.
Type:
Application
Filed:
February 2, 2012
Publication date:
November 26, 2015
Applicant:
AXIAL BIOTECH, INC.
Inventors:
Rakesh N. Chettier, Lesa M. Nelson, Kenneth Ward, James W. Ogilvie, Roberto A. Macina
Abstract: The present invention relates to novel genetic markers associated with scoliosis, risk of developing scoliosis and risk of scoliosis curve progression, and simplified methods and materials for determining whether a human subject has scoliosis, is at risk of developing scoliosis or is at risk of scoliosis curve progression.
Type:
Application
Filed:
June 19, 2012
Publication date:
October 11, 2012
Applicant:
AXIAL BIOTECH, INC.
Inventors:
Michael R. Schramm, James W. Ogilvie, Lesa M. Nelson, Kenneth Ward, Rakesh N. Chettier
Abstract: The present invention is a bone growth stimulating and promoting cytokine type biological implant preferably comprising PTH coated with a controlled release biodegradable coating that is implanted preferably in the concave side of a scoliotically curved spine in combination with a bone growth inhibiting type biological implant preferably comprising methotrexate or like anti-metabolite coated with a controlled release biodegradable coating that is implanted preferably in the convex side of a scoliotically curved spine. The insertion of the biological implant is highly non-invasion, especially as compared to more conventional spine surgical methods, and the biological implant does not decrease spinal mobility or spinal range of motion.
Abstract: The present invention relates to novel genetic markers associated with degenerative disc disease (DDD), risk of developing DDD and risk of DDD progression, and methods and materials for determining whether a human subject has DDD, is at risk of developing DDD or is at risk of DDD progression.
Type:
Application
Filed:
July 1, 2009
Publication date:
January 7, 2010
Applicant:
Axial Biotech, Inc.
Inventors:
Rakesh N. Chettier, Lesa M. Nelson, Kenneth Ward, James W. Ogilvie, Roberto A. Macina
Abstract: The present invention is a bone growth stimulating and promoting cytokine type biological implant preferably comprising PTH coated with a controlled release biodegradable coating that is implanted preferably in the concave side of a scoliotically curved spine in combination with a bone growth inhibiting type biological implant preferably comprising methotrexate or like anti-metabolite coated with a controlled release biodegradable coating that is implanted preferably in the convex side of a scoliotically curved spine. The insertion of the biological implant is highly non-invasion, especially as compared to more conventional spine surgical methods, and the biological implant does not decrease spinal mobility or spinal range of motion.
Abstract: The present invention relates to novel genetic markers associated with scoliosis, risk of developing scoliosis and risk of scoliosis curve progression, and simplified methods and materials for determining whether a human subject has scoliosis, is at risk of developing scoliosis or is at risk of scoliosis curve progression.
Type:
Application
Filed:
December 18, 2008
Publication date:
April 23, 2009
Applicant:
Axial Biotech, Inc.
Inventors:
Michael R. Schramm, James W. Ogilvie, Lesa M. Nelson, Ward Kenneth, Rakesh N. Chettier
Abstract: The present invention relates to novel genetic markers associated with scoliosis, risk of developing scoliosis and risk of scoliosis curve progression, and methods and materials for determining whether a human subject has scoliosis, is at risk of developing scoliosis or is at risk of scoliosis curve progression.
Abstract: The invention is a three-contact-point dynamic scoliosis orthosis (DSO) brace to aid physicians treating scoliosis. A pelvic mold and two pads, one positioned above the apex of the spine curvature, the other positioned orthogonal to the apex of the spine curvature provide the anchor points on opposite sides of the curve. The pad orthogonal to the curve's apex is adjustable.