Patents Assigned to Axim Biotechnologies, Inc.
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Patent number: 11714083Abstract: The presence of analytes can be detected in the bodily fluid using Electrochemical Impedance Spectroscopy (EIS) or Electrochemical Capacitance Spectroscopy (ECS) in devices, such as handheld point-of-care devices. The devices, as well as systems and methods, utilize using Electrochemical Impedance Spectroscopy (EIS) or Electrochemical Capacitance Spectroscopy (EIS) in combination with an antibody or other target-capturing molecule on a working electrode. Imaginary impedance or phase shift, as well as background subtraction, also may be utilized.Type: GrantFiled: May 4, 2018Date of Patent: August 1, 2023Assignees: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, AXIM BIOTECHNOLOGIES. INC.Inventors: Jeffrey LaBelle, Garrett Repp, Chi Lin, Mark Spano, Jennifer Blain Christen, Hongwu Jiang, Marcus Smith, Andrew Penman, Pierce Youngbar, Mackenzie Honikel, Curtiss Cook
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Patent number: 11542226Abstract: This invention discloses cannabinoids linked with polyethylene glycol chains. The cannabinoid-polyethylene glycol chain molecules have one, two, or more cannabinoids linked with one, two, or more polyethylene glycol chains. Each cannabinoid-polyethylene glycol chain molecule may have one kind of cannabinoid or multiple kinds of cannabinoid. Methods to make these cannabinoid-polyethylene glycol linked chains are disclosed.Type: GrantFiled: April 13, 2021Date of Patent: January 3, 2023Assignee: Axim Biotechnologies, Inc.Inventors: Sergei Svarovsky, John W. Huemoeller, II
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Patent number: 10543190Abstract: This invention relates to a suppository composition comprising cannabinoids. The suppository composition is formulated for easy absorption through mucosal membrane. The suppository as provided herein is useful for administration of cannabinoids in patients with nausea, vomiting, other conditions preventing swallowing, or conditions wherein suppository administration is required. Methods to manufacture the suppository composition are provided. Methods to treat pain, nausea, post-operative ileus and/or inflammatory bowel diseases using the suppository according to this invention are also provided.Type: GrantFiled: September 5, 2018Date of Patent: January 28, 2020Assignee: Axim Biotechnologies, Inc.Inventors: Lekhram Changoer, George Anastassov
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Patent number: 10441552Abstract: This invention discloses anti-bacterial and anti-fungal compositions in spray form, in cream form, in liquid form, and in powder form. The anti-bacterial and anti-fungal compositions comprise cannabinoids, specifically cannabidiol, cannabigerol, tetrahydrocannabinol, tetracannabidivarin, and/or cannabidivarin for anti-bacterial and anti-fungal activities. The anti-bacterial and anti-fungal compositions may be used to treat toe nail fungus, MRSA infection, herpes virus infection, tinea pedis, burn wound infections, sun burns, diabetic infections, eczema, impetigo, dermatophytosis, psoriasis, itchy skin, atopic dermatitis, dandruff, and general topical infections.Type: GrantFiled: March 5, 2019Date of Patent: October 15, 2019Assignee: Axim Biotechnologies, Inc.Inventors: George E. Anastassov, Lekhram Changoer, Philippus Anne Van Damme
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Patent number: 10272051Abstract: A method to treat the skin condition atopic dermatitis is described in this invention. The method comprises topical application of a composition containing cannabinoids, specifically cannabidiol and cannabigerol at a concentration of 3%-20% by weight of the composition. The method may further comprise administering chewing gum containing cannabinoids such as cannabidiol. Cannabidiol and cannabigerol may be sourced naturally or synthetically.Type: GrantFiled: August 21, 2018Date of Patent: April 30, 2019Assignee: Axim Biotechnologies, Inc.Inventors: Lekhram Changoer, George Anastassov
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Patent number: 10246431Abstract: ?9-THC carboxylic acid is extracted from cannabis flowers using a first organic solvent, then separated using a second aqueous solvent. ?9-THC carboxylic acid is converted to ?9-THC carboxylic salt before being extracted by a third organic solvent and converted back to ?9-THC carboxylic acid. Using a solvent swap, ?9-THC carboxylic acid is decarboxylated and extracted again with an organic solvent prior to purification to give ?9-THC.Type: GrantFiled: August 1, 2018Date of Patent: April 2, 2019Assignee: Axim Biotechnologies, Inc.Inventors: Lekhram Changoer, Cornelis Herman Michel Van Der Loo, Erik Keller
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Patent number: 10172786Abstract: This application discloses oral care compositions comprising cannabinoids, preferably cannabidiol and/or cannabigerol. The oral care composition disclosed in this application may be a tooth paste, a tooth powder, or a mouthwash solution. The oral care composition may be used to treat oral infectious disease, including periimplantitis, periodontitis, oral mucositis, and dental pain.Type: GrantFiled: December 15, 2015Date of Patent: January 8, 2019Assignee: Axim Biotechnologies, Inc.Inventors: George Anastassov, Lekhram Changoer
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Patent number: 10092538Abstract: This invention relates to a suppository composition comprising cannabinoids. The suppository composition is formulated for easy absorption through mucosal membrane. The suppository as provided herein is useful for administration of cannabinoids in patients with nausea, vomiting, other conditions preventing swallowing, or conditions wherein suppository administration is required. Methods to manufacture the suppository composition are provided. Methods to treat pain, nausea, post-operative ileus and/or inflammatory bowel diseases using the suppository according to this invention are also provided.Type: GrantFiled: October 19, 2017Date of Patent: October 9, 2018Assignee: Axim Biotechnologies, Inc.Inventors: Lekhram Changoer, George Anastassov
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Patent number: 10059684Abstract: ?9-THC acid is extracted from cannabis flowers using a first organic solvent, then separated using a second aqueous solvent. ?9-THC acid is converted to ?9-THC carboxylic salt before being extracted by a third organic solvent and converted back to ?9-THC carboxylic acid. Using a solvent swap, ?9-THC carboxylic acid is decarboxylated and extracted again with an organic solvent prior to purification to give ?9-THC.Type: GrantFiled: May 4, 2016Date of Patent: August 28, 2018Assignee: Axim Biotechnologies, Inc.Inventors: Lekhram Changoer, Cornelis Herman Michel Van Der Loo, Erik Keller
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Patent number: 9844530Abstract: This invention generally relates to methods of treatment of glaucoma and symptomatic relief of conjunctival inflammation. An ophthalmic solution comprising cannabinoids for the treatment of glaucoma and an ophthalmic solution comprising cannabinoids for these purposes are disclosed. Cannabinoids are selected to achieve the specific purpose of the respective ophthalmic solution.Type: GrantFiled: October 9, 2017Date of Patent: December 19, 2017Assignee: Axim Biotechnologies, Inc.Inventors: George Anastassov, Lekhram Changoer
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Patent number: 9814695Abstract: This invention generally relates to an ophthalmic solution comprising cannabinoids for the treatment of glaucoma. Also disclosed is an ophthalmic solution comprising cannabinoids for symptomatic relief of conjunctival inflammation. Cannabinoids are selected to achieve the specific purpose of the respective ophthalmic solution.Type: GrantFiled: December 29, 2015Date of Patent: November 14, 2017Assignee: Axim Biotechnologies, Inc.Inventors: George Anastassov, Lekhram Changoer