Abstract: Gymnema sylvestre extracts together with extracts of one or more of Boswellia serrata, Tinospora cordifolia and Commiphora mukul provide effective weight loss management when administered to a patient desiring weight loss management. Administration of the foregoing also reduces the leptin-to-adiponectin ratio in the patient's blood serum.

Abstract: Gurmarin containing compositions are useful for modulation of glucose metabolism and the treatment of diabetes. Glucose metabolism in a human patient is regulated by isolated gurmarin-containing dosage forms that optionally contain a non-metabolizable polysaccharide such as the exudate of Sterculia urens.

Abstract: Gurmarin containing compositions are useful for modulation of glucose metabolism and the treatment of diabetes. Glucose metabolism in a human patient is regulated by isolated gurmarin-containing dosage forms that contain optionally a non-metabolizable polysaccharide such as the exudate of Sterculia urens.

Abstract: Gurmarin containing compositions are useful for the treatment of diabetes. Glucose metabolism in a human patient is regulated by gurmarin-containing dosage forms that contain optionally a non-metabolizable polysaccharide such as the exudate of Sterculia urens.

Abstract: An isolate from the leaves of Gymnema sylvestre, having a specified molecular weight, is useful for the treatment of diabetes. The isolate has a molecular weight at least about 3000 Daltons as determined by molecular weight cut-off filtration. Glucose metabolism in a human patient is regulated by dosage forms that contain the aforesaid isolate from the leaves of Gymnema sylvestre, optionally in combination with a non-metabolizable polysaccharide such as the exudate of Sterculia urens.

Abstract: An oral composition, suitable as a hypoglycemic agent, includes an isolate from the leaves of Gymnema sylvestre, having a specified molecular weight. The isolate has a molecular weight at least about 3000 Daltons as determined by molecular weight cut-off filtration. Glucose metabolism in a human patient can be regulated by dosage forms that contain the aforesaid isolate from the leaves of Gymnema sylvestre, in combination with a non-metabolizable, water-swellable polysaccharide such as the exudate of Sterculia urens, and a water-soluble polysaccharide such as guar gum. Optionally, the present oral compositions can include a physiologically acceptable calcium source, a physiologically acceptable metal carbonate salt, a physiologically acceptable chromium salt, and/or a physiologically acceptable vanadium compound. In addition, antioxidants such as ascorbic acid, cholecalciferol, d-?-tocopherol, the carotenoids, lycopene, lutein, and the like, can be included as well.