Patents Assigned to AZICO BIOPHORE INDIA PRIVATE LIMITED
  • Process for the preparation of levothyroxine sodium
    Patent number: 9428444
    Abstract: The present invention provides a novel process for the preparation of highly pure Levothyroxine Sodium, i.e., (S)-2-amino-3-[4-(4-hydroxy-3, 5-diiodophenoxy)-3,5-diiodophenyl] propanoic acid sodium salt via two process intermediates viz 3,5-Diiodo L-Tyrosine copper complex and novel Bis (p-anisyl) iodonium Iodide. The invention also provides levothyroxine pentahydrate free from genotoxic impurities and liothyronine levels below 0.04% wt/wt.
    Type: Grant
    Filed: January 30, 2014
    Date of Patent: August 30, 2016
    Assignee: AZICO BIOPHORE INDIA PRIVATE LIMITED
    Inventors: Ch. A. P. Rameswara Rao, Sreenath Dasari
  • NOVEL PROCESS FOR THE PREPARATION OF LEVOTHYROXINE SODIUM
    Publication number: 20160168076
    Abstract: The present invention provides a novel process for the preparation of highly pure Levothyroxine Sodium, i.e., (S)-2-amino-3-[4-(4-hydroxy-3, 5-diiodophenoxy)-3,5-diiodophenyl] propanoic acid sodium salt via two process intermediates viz 3,5-Diiodo L-Tyrosine copper complex and novel Bis (p-anisyl) iodonium Iodide. The invention also provides levothyroxine pentahydrate free from genotoxic impurities and liothyronine levels below 0.04% wt/wt.
    Type: Application
    Filed: January 30, 2014
    Publication date: June 16, 2016
    Applicant: AZICO BIOPHORE INDIA PRIVATE LIMITED
    Inventors: Ch. A.P. Rao, Sreenath Dasari