Patents Assigned to AZTHERAPIES, INC
  • Patent number: 11291648
    Abstract: The present disclosure is directed to a composition comprising micronized cromolyn sodium, ?-lactose, and a salt of fatty acid, wherein the ?-lactose has a particle size distribution of D90 of 45-70 ?m, D50 of 10-35 ?m, and D10 of 2-13 ?m. The present disclosure is also directed to a method of treating Alzheimer's disease, amyloidosis-associated condition (AAC), traumatic brain injury, Huntington's disease, atherosclerosis, cytokine release syndrome (CRS), dementia, head injury, infection, neuroinflammation, prion disease, stroke, amyotrophic lateral sclerosis (ALS), Parkinson's disease, or asthma using the composition.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: April 5, 2022
    Assignees: The General Hospital Corporation, AZTherapies, Inc.
    Inventors: David R. Elmaleh, Juan B. Gonzalez
  • Patent number: 10561612
    Abstract: The invention is directed to a composition comprising cromolyn sodium and ibuprofen, wherein the cromolyn sodium is micronized and the cromolyn sodium and ibuprofen are present in a weight ratio of 1:1-2. In one embodiment, the ibuprofen is passed through a sieve, such as a 300 ?m sieve and to methods of making the same.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: February 18, 2020
    Assignees: The General Hospital Corporation, AZTherapies, Inc.
    Inventors: David R. Elmaleh, Juan B. Gonzalez
  • Publication number: 20190022006
    Abstract: The invention is directed to a composition comprising cromolyn sodium and ibuprofen, wherein the cromolyn sodium is micronized and the cromolyn sodium and ibuprofen are present in a weight ratio of 1:1-2. In one embodiment, the ibuprofen is passed through a sieve, such as a 300 ?m sieve and to methods of making the same.
    Type: Application
    Filed: December 12, 2017
    Publication date: January 24, 2019
    Applicant: AZTherapies, Inc.
    Inventors: David R. ELMALEH, Juan B. Gonzalez
  • Publication number: 20180344682
    Abstract: The invention is directed to methods of treating ischemic stroke by adminis-tering a therapeutically effective amount of at least one compound of Formula I or Formula II to a subject in need thereof, wherein the compound has Formula I or Formula II: or a salt or ester of (I) or (II); wherein X is OH, C1-C6 alkoxyl, 18F, or 19F; Y and Z are independently selected from C1-C6 alkyl, C1-C6 alkoxyl, halogen, substituted or unsubstituted C1-C6 amine, 18F, 19F, or H; and n is 1, 2, or 3.
    Type: Application
    Filed: November 23, 2016
    Publication date: December 6, 2018
    Applicant: AZTherapies, Inc.
    Inventor: David R. ELMALEH
  • Publication number: 20180325862
    Abstract: The invention is directed to a method of treating Alzheimer's Disease by administering to a subject in need thereof a therapeutically effective amount of cromolyn and optionally ibuprofen. The cromolyn may be in the form of cromolyn sodium and administered by inhalation.
    Type: Application
    Filed: November 21, 2016
    Publication date: November 15, 2018
    Applicant: AZTherapies, Inc.
    Inventor: David R. ELMALEH
  • Publication number: 20180153803
    Abstract: Methods of delivering cromolyn to a patient in need thereof, methods of treating amyloid-associated conditions and inflammatory or allergic lung diseases, and packs and kits comprising cromolyn are described.
    Type: Application
    Filed: December 4, 2017
    Publication date: June 7, 2018
    Applicant: AZTHERAPIES, INC
    Inventor: David R. ELMALEH
  • Patent number: 9861608
    Abstract: Methods of delivering cromolyn to a patient in need thereof, methods of treating amyloid-associated conditions and inflammatory or allergic lung diseases, and blister packs and kits comprising cromolyn are described.
    Type: Grant
    Filed: May 22, 2014
    Date of Patent: January 9, 2018
    Assignee: AZTHERAPIES, INC
    Inventors: David R. Elmaleh, Alex Franzusoff
  • Publication number: 20160106704
    Abstract: Methods of delivering cromolyn to a patient in need thereof, methods of treating amyloid-associated conditions and inflammatory or allergic lung diseases, and blister packs and kits comprising cromolyn are described.
    Type: Application
    Filed: May 22, 2014
    Publication date: April 21, 2016
    Applicant: AZTHERAPIES, INC
    Inventors: DAVID R. ELMALEH, ALEX FRANZUSOFF