Patents Assigned to AZYP, LLC
  • Superficially porous particle (SPP) chiral phases for liquid chromatography
    Patent number: 10272364
    Abstract: The present invention relates to a novel stationary phase support for liquid chromatographic chiral separations. The specific combination of the special underlying support material and certain classes of known chiral selectors according to the invention produces far superior chiral (enantiomeric) separations than those obtained on any conventionally known supports. These chiral (enantiomeric) separations are enhanced in terms of significantly higher efficiencies (theoretical plate numbers), higher resolutions (Rs), shorter retention times and either equivalent or slightly higher selectivities than those obtained on conventional supports.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: April 30, 2019
    Assignee: AZYP, LLC
    Inventors: Daniel W. Armstrong, Zachary S. Breitbach
  • High efficiency, ultra-stable, bonded hydrophilic interaction chromatography (HILIC) matrix on superficially porous particles (SPPS)
    Patent number: 10265643
    Abstract: The present invention relates to superficially porous particles (SPPs), also called core-shell, porous shell or fused core particles, which are state-of-the-art support materials used in the production of HPLC columns. Hydrolytically stable, highly selective superficially porous particle (SPP) hydrophilic interaction liquid chromatographic (HILIC) stationary phases having higher efficiencies and shorter retention times than analogous stationary phases on fully porous particles (FPP) is provided.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: April 23, 2019
    Assignee: AZYP, LLC
    Inventors: Daniel W. Armstrong, Zachry S. Breitbach
  • NEW ULTRAHIGH EFFICIENCY, SUPERFICIALLY POROUS PARTICLE (SPP) CHIRAL PHASES FOR LIQUID CHROMATOGRAPHY
    Publication number: 20170197156
    Abstract: The present invention relates to a novel stationary phase support for liquid chromatographic chiral separations. The specific combination of the special underlying support material and certain classes of known chiral selectors according to the invention produces far superior chiral (enantiomeric) separations than those obtained on any conventionally known supports. These chiral (enantiomeric) separations are enhanced in terms of significantly higher efficiencies (theoretical plate numbers), higher resolutions (Rs), shorter retention times and either equivalent or slightly higher selectivities than those obtained on conventional supports.
    Type: Application
    Filed: July 17, 2015
    Publication date: July 13, 2017
    Applicant: AZYP, LLC
    Inventors: Daniel W. ARMSTRONG, Zachary S BREITBACH
  • Chromatographic separation material
    Patent number: 9302203
    Abstract: The chromatographic separation material is a cyclofructan or a derivative of cyclofructan covalently bonded to a cross-linked, organic polymer. The separation material works well in hydrophilic interaction liquid chromatography.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: April 5, 2016
    Assignees: MITSUBISHI CHEMICAL CORPORATION, AZYP, LLC
    Inventors: Haixiao Qiu, Daniel W. Armstrong, Mayumi Kiyono-Shimobe