Abstract: Disclosed is an aneurysm clip pliers for applying an aneurysm clip to a blood vessel. The pliers have a hand grip end and a barrel end. A pusher bar reciprocates within the hollow barrel portion causing the Y-shaped clip grip to open or close, depending upon the position of the push rod. A trigger mechanism causes the spring loaded pusher bar to shift toward the Y-shaped grip when the trigger is squeezed. A locking mechanism enables an aneurysm clip to be placed between the arms of the Y-shaped grip and retained therein until the aneurysm clip is to be applied on the blood vessel. The barrel end is rotatable through 360.degree. with respect to the hand grip end of the aneurysm clip pliers, and the Y-shaped grip permits the aneurysm clip to pivot about an arc slightly larger than 180.degree.. Accordingly, positioning the aneurysm clip on the defective blood vessel is easily accomplished.