Abstract: A method of precipitating low-density lipoproteins which comprises administering to a volume of blood, plasma or solutions containing blood or plasma a therapeutically or diagnostically effective amount of a low-density lipoprotein precipitating substance at an acid pH such that an anticoagulent effect associated with heparin is minimized or eliminated. The substances utilized in such a method include hydrolyzed heparin, hydrolyzed heparin acylated at free amine groups, sulfated glycosamino glycan and sulfated polysaccharides.
Type:
Grant
Filed:
November 20, 1987
Date of Patent:
March 13, 1990
Assignee:
B. Braun-SSG AG
Inventors:
Dietrich Seidel, Heinrich Wieland, Gerhard Rosskopf, Wolfgang Feller