Abstract: The present invention discloses a bacteriorhodopsin-containing bioactive gel and a method for fabricating the same, wherein a thickening polymeric compound is suspended in water to form a base gel having appropriate glutinosity and suitable for skin, and wherein a bacteriorhodopsin-containing culture fluid, which is obtained via culturing halobacteria in a spent culture fluid, is integrated with the glutinous base gel to form the bacteriorhodopsin-containing bioactive gel. The bioactive gel of the present invention is abundant of vitamins, minerals, amino acids, etc. and thus very useful in beauty treatment and dermatological treatment. The present invention is also expected to have high commercial potential in many other fields.