Abstract: The invention relates to containers for the drying, especially the freeze-drying, of material. In particular, the invention relates to a lid of a drying container, said lid enabling to close the container body of the drying container so as to avoid i) contamination of the material to be dried inside the container and ii) spills of airborne solid particles of said material from the container to the environment. The lid comprises a lower and an upper frame with a vapor permeable sheet positioned in between. The invention further provides methods for the drying, especially the freeze-drying, of material.
Abstract: The present invention relates to methods and compounds for the solid phase synthesis of peptides carrying a substituent at an amino group of an amino acid side chain.
Abstract: The present invention relates to methods and compounds for the solid phase synthesis of peptides carrying a substituent at an amino group of an amino acid side chain.
Abstract: The present invention refers to a method of purifying a glucagon-like peptide 1 analogs, the method comprising a two dimensional reversed phase high performance liquid chromatography protocol, wherein the first step is carried out at a pH value between 7.0 to 7.8 using a mobile phase comprising a phosphate buffer and acetonitrile, and the second step is carried out at a pH value below 3.0 using a mobile phase comprising trifluoroacetic acid and acetonitrile.
Type:
Application
Filed:
June 5, 2020
Publication date:
November 26, 2020
Applicant:
BACHEM HOLDING AG
Inventors:
Andreas STADELMAIER, Ralph O. SCHOENLEBER, Daniel SAMSON, Frank DETTNER
Abstract: The present invention refers to a method of purifying a glucagon-like peptide 1 analogs, the method comprising a two dimensional reversed phase high performance liquid chromatography protocol, wherein the first step is carried out at a pH value between 7.0 to 7.8 using a mobile phase comprising a phosphate buffer and acetonitrile, and the second step is carried out at a pH value below 3.0 using a mobile phase comprising trifluoroacetic acid and acetonitrile.
Type:
Grant
Filed:
March 21, 2017
Date of Patent:
June 23, 2020
Assignee:
BACHEM HOLDING AG
Inventors:
Andreas Stadelmaier, Ralph O. Schoenleber, Daniel Samson, Frank Dettner
Abstract: The present invention refers to a method of purifying a glucagon-like peptide 1 analogs, the method comprising a two dimensional reversed phase high performance liquid chromatography protocol, wherein the first step is carried out at a pH value between 7.0 to 7.8 using a mobile phase comprising a phosphate buffer and acetonitrile, and the second step is carried out at a pH value below 3.0 using a mobile phase comprising trifluoroacetic acid and acetonitrile.
Type:
Application
Filed:
March 21, 2017
Publication date:
April 18, 2019
Applicant:
BACHEM HOLDING AG
Inventors:
Andreas STADELMAIER, Ralph O. SCHOENLEBER, Daniel SAMSON, Frank DETTNER