Abstract: The present invention provides a serum and its blood components isolated from blood, wherein the blood is drawn from body of a patient, and a normal saline solution mixed with the serum and its blood components, characterized in that a Reagent A having at least one type of adjuvant, and a Reagent B having at least one type of transfer factor peptide and a buffered saline, and Reagent C having an alpha lipoic acid are added to the mixture of the serum and its blood components and the normal saline solution, such that the composition enhances cell-mediated immunity and T suppressor cells in the patient to act against autoimmune disease. The present invention also provides a method for producing such composition for immunotherapy thereof.