Patents Assigned to Baker Cumins Dermatologicals, Inc.
  • Method of treating pruritus with nalmefene and clonidine
    Patent number: 4946848
    Abstract: A method of treating a mammal suffering from pruritus, whether antigen-induced or disease-induced, comprising orally administering to the subject from about 1 to about 25 mg of the narcotic antagonist nalmefene for an initial period of 1 to 7 days, and gradually increasing the dosage level of nalmefene by increments of 1 to 25 mg per day during successive periods of 1 to 7 days to a maximum of 150 mg per day. Clonidine or clonidine hydrochloride may be administered concomitantly with the nalmefene to alleviate opioid withdrawal symptoms.
    Type: Grant
    Filed: February 21, 1989
    Date of Patent: August 7, 1990
    Assignee: Baker Cumins Dermatologicals, Inc.
    Inventors: Ronald R. Tuttle, J. R. Thornton