Patents Assigned to Baker Heart Research Institute
  • Publication number: 20120178668
    Abstract: The present invention discloses proteinaceous compounds that comprise at least a biologically active portion of a taipan natriuretic peptide (TNP) or a variant or derivative thereof. The invention also relates to the use of these compounds in methods for stimulating vasodilation, natriuresis, diuresis, renin-suppression, bactericidal activity, weight-loss or bone growth in a mammalian host. In specific embodiments, the compounds are useful in the treatment of congestive heart failure.
    Type: Application
    Filed: November 10, 2011
    Publication date: July 12, 2012
    Applicants: BAKER HEART RESEARCH INSTITUTE, THE UNIVERSITY OF QUEENSLAND
    Inventors: Paul Alewood, Geoffrey A. Head, Brian Fry
  • Patent number: 8058242
    Abstract: The present invention discloses proteinaceous compounds that comprise at least a biologically active portion of a taipan natriuretic peptide (TNP) or a variant or derivative thereof. The invention also relates to the use of these compounds in methods for stimulating vasodilation, natriuresis, diuresis, renin-suppression, bactericidal activity, weight-loss or bone growth in a mammalian host. In specific embodiments, the compounds are useful in the treatment of congestive heart failure.
    Type: Grant
    Filed: January 15, 2007
    Date of Patent: November 15, 2011
    Assignees: The University of Queensland, Baker Heart Research Institute
    Inventors: Paul Alewood, Geoffrey A. Head, Bryan Fry
  • Publication number: 20080153747
    Abstract: The present invention discloses proteinaceous compounds that comprise at least a biologically active portion of a taipan natriuretic peptide (TNP) or a variant or derivative thereof. The invention also relates to the use of these compounds in methods for stimulating vasodilation, natriuresis, diuresis, renin-suppression, bactericidal activity, weight-loss or bone growth in a mammalian host. In specific embodiments, the compounds are useful in the treatment of congestive heart failure.
    Type: Application
    Filed: January 15, 2007
    Publication date: June 26, 2008
    Applicants: The University of Queensland, Baker Heart Research Institute
    Inventors: Paul Alewood, Geoffrey A. Head, Bryan Fry