Abstract: Described is a method of supplying an active ingredient to a location beneath the outer layer of skin or into soft tissue which includes the steps of providing a polymer-containing liquid comprising an active ingredient; subjecting the liquid issuing from an outlet to an electric field to cause the liquid to form at least one electrically charged jet that breaks up to provide charged fiber fragments or fibrils containing an active ingredient, the fiber fragments or fibrils being capable of sticking onto the outer layer of skin or soft tissue to supply the active ingredient beneath the outer layer of skin or soft tissue; and contacting skin with the fiber fragments or fibrils.