Patents Assigned to BALTIC TECHNOLOGY DEVELPMENT, LTD.
  • Use of Oligonucleotides with Modified Bases as Antiviral Agents
    Publication number: 20110171287
    Abstract: The present invention relates to the use of oligonucleotides having modified nucleobases to inhibit gene expression and/or replication of viruses in a subject. The modified nucleobases may be mercapto-modified bases or hydroxy-modified nucleobases. It is contemplated that the oligonucleotides further comprise a nuclease complex which enhances anti-viral activity of the oligonucleotides.
    Type: Application
    Filed: November 5, 2008
    Publication date: July 14, 2011
    Applicant: BALTIC TECHNOLOGY DEVELPMENT, LTD.
    Inventors: Mart Saarma, Andres Merits, Mati Karelson