Patents Assigned to BANGALORE UNIVERSITY
  • Small molecule inhibitors of BCL-2-associated death promoter (BAD) phosphorylation
    Patent number: 11292773
    Abstract: The invention relates to compounds of general formula (I): wherein R1, n, R2a, R2b, and R3 are as defined herein. The compounds are inhibitors of Bcl-2-associated death promoter (BAD) phosphorylation and have anti-apoptotic activity and are useful in the treatment of cancer, particularly breast cancer, endometrial cancer, ovarian cancer, liver cancer, colon cancer, prostate cancer or pancreatic cancer.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: April 5, 2022
    Assignees: NATIONAL UNIVERSITY OF SINGAPORE, UNIVERSITY OF MYSORE, BANGALORE UNIVERSITY
    Inventors: Peter Edward Lobie, Vijay Kumar Pandey, Rangappa Kanchugarakoppal Subbegowda, Bassappa Salundi, Mohan Chakrabhavi Dhananjaya, Shobith Rangappa, Srinivasa Venkatachalaiah
  • Compounds useful in inhibiting human trefoil factor 3
    Patent number: 11141402
    Abstract: Disclosed herein are compounds of Formula I, wherein A, R1 to R6, and x to z have the meanings given in the description.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: October 12, 2021
    Assignees: National University of Singapore, University of Mysore, Bangalore University
    Inventors: Peter Edward Lobie, Vijay Kumar Pandey, Rangappa Kanchugarakoppal Subbegowda, Basappa, Mohan Chakrabhavi Dhananjaya, Shobith Rangappa
  • Compounds as modulator of JAK-STAT pathway, methods and applications thereof
    Patent number: 9604974
    Abstract: The present disclosure relates to compound of structural Formula I and a method for preparing said compounds. The disclosure further relates to a method of employing the Formula I compounds for modulation of Janus kinase-Signal Transducer and Activator of Transcription (JAK-STAT) pathway in cancer cells, and the corresponding use of compound of Formula I as anti-cancer agents.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: March 28, 2017
    Assignees: UNIVERSITY OF MYSORE, NATIONAL UNIVERSITY OF SINGPORE, BANGALORE UNIVERSITY, CAMBRIDGE ENTERPRISE LTD
    Inventors: Kanchugarakoppal Subbegowda Rangappa, Basappa, Chakrabhavi Dhananjaya Mohan, Shobith Rangappa, Hanumantharayappa Bharathkumar, Gautam Sethi, Andreas Bender, Peter Edward Lobie, Kam Man Hui, Alan Prem Kumar, Vijay Kumar Pandey, Julian Fuchs, Muthu Kumaraswamy Shanmugam, Krishna Bulusu, Xiaoyun Dai, Feng Li, Amudha Deivasigamani