Patents Assigned to Banner Life Sciences LLC
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Patent number: 11903918Abstract: Described herein are pharmaceutical compositions comprising one or more fumarate esters and methods for treating multiple sclerosis subjects with the compositions where the incidence of gastrointestinal side effects is reduced compared to treatments comprising dimethyl fumarate (e.g., TECFIDERA®). In particular, described herein are oral pharmaceutical compositions comprising monomethyl fumarate in a liquid vehicle that have reduced gastrointestinal side effects.Type: GrantFiled: January 7, 2021Date of Patent: February 20, 2024Assignee: BANNER LIFE SCIENCES LLCInventors: Franck S. F. Rousseau, Thomas Wallace Lategan, Tiffany Nicole Sprague, Jason Michael Vaughn, Justin Roy Hughey
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Patent number: 11590095Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral controlled release pharmaceutical compositions comprising fumarate esters suspended in liquid matrices are described. One embodiment described herein is a pharmaceutical composition comprising fumarate esters suspended in a lipid or lipophilic liquid with enhanced bioavailability.Type: GrantFiled: January 13, 2021Date of Patent: February 28, 2023Assignee: BANNER LIFE SCIENCES LLCInventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 10945985Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral controlled release pharmaceutical compositions comprising fumarate esters suspended in liquid matrices are described. One embodiment described herein is a pharmaceutical composition comprising fumarate esters suspended in a lipid or lipophilic liquid with enhanced bioavailability.Type: GrantFiled: September 13, 2018Date of Patent: March 16, 2021Assignee: BANNER LIFE SCIENCES LLCInventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 10918616Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.Type: GrantFiled: September 13, 2018Date of Patent: February 16, 2021Assignee: BANNER LIFE SCIENCES LLCInventors: Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 10918617Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.Type: GrantFiled: September 13, 2018Date of Patent: February 16, 2021Assignee: BANNER LIFE SCIENCES LLCInventors: Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 10918615Abstract: Described herein are pharmaceutical compositions comprising one or more fumarate esters, processes for making the same, and compositions and methods for treating multiple sclerosis subjects with the compositions. In particular, oral pharmaceutical compositions comprising fumarate esters in liquid vehicles are described. One embodiment is an oral delayed release pharmaceutical dosage form comprising a soft capsule encapsulating an immediate releasing liquid comprising one or more fumarate esters.Type: GrantFiled: September 13, 2018Date of Patent: February 16, 2021Assignee: BANNER LIFE SCIENCES LLCInventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 10105336Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.Type: GrantFiled: October 12, 2017Date of Patent: October 23, 2018Assignee: Banner Life Sciences LLCInventors: Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 10105337Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.Type: GrantFiled: October 12, 2017Date of Patent: October 23, 2018Assignee: Banner Life Sciences LLCInventors: Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 10105335Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral controlled release pharmaceutical compositions comprising fumarate esters suspended in liquid matrices are described. One embodiment described herein is a pharmaceutical composition comprising fumarate esters suspended in a lipid or lipophilic liquid with enhanced bioavailability.Type: GrantFiled: October 12, 2017Date of Patent: October 23, 2018Assignee: Banner Life Sciences LLCInventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 10098863Abstract: Described herein are pharmaceutical compositions comprising one or more fumarate esters, processes for making the same, and compositions and methods for treating multiple sclerosis subjects with the compositions. In particular, oral pharmaceutical compositions comprising fumarate esters in liquid vehicles are described. One embodiment is an oral delayed release pharmaceutical dosage form comprising a soft capsule encapsulating an immediate releasing liquid comprising one or more fumarate esters.Type: GrantFiled: August 25, 2017Date of Patent: October 16, 2018Assignee: Banner Life Sciences LLCInventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 9943513Abstract: Described herein are oral abuse deterrent pharmaceutical compositions, methods for making the same, and methods for treating pain by administering the pharmaceutical composition to a subject in need thereof. In particular, an oral abuse deterrent pharmaceutical composition comprising a soft capsule and a controlled release matrix comprising oxycodone are described.Type: GrantFiled: October 5, 2016Date of Patent: April 17, 2018Assignee: BANNER LIFE SCIENCES LLCInventors: Justin Hughey, Saujanya Gosangari, Chue Hue Yang
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Patent number: 9877971Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising non-systemic corticosteroid soft lozenges, methods for making the same, and methods for treating subjects in need thereof with such lozenges. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the oral pharmaceutical compositions comprise chewable, suckable, or buccally-dissolvable soft lozenges for the treatment of esophageal lesions. The soft lozenges provide topical, non-systemic delivery of corticosteroids to the esophagus and oral cavity.Type: GrantFiled: June 14, 2016Date of Patent: January 30, 2018Assignee: Banner Life Sciences LLCInventors: Yinyan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Patent number: 9867834Abstract: Described herein are topical, non-systemic, slow releasing oral pharmaceutical compositions, methods for making the same, and methods for treating subjects in need thereof with such compositions. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the pharmaceutical composition provides topical corticosteroids to the esophagus and oral cavity.Type: GrantFiled: October 14, 2016Date of Patent: January 16, 2018Assignee: Banner Life Sciences LLCInventors: Yinyan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Patent number: 9861629Abstract: Described herein are oral abuse deterrent pharmaceutical compositions, methods for making the same, and methods for treating pain by administering the pharmaceutical composition to a subject in need thereof. In particular, an oral abuse deterrent pharmaceutical composition comprising a soft capsule and a controlled release matrix comprising oxycodone are described.Type: GrantFiled: October 5, 2016Date of Patent: January 9, 2018Assignee: Banner Life Sciences LLCInventors: Justin Hughey, Saujanya Gosangari, Chue Hue Yang
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Patent number: 9820960Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.Type: GrantFiled: November 22, 2016Date of Patent: November 21, 2017Assignee: Banner Life Sciences LLCInventors: Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 9820961Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral controlled release pharmaceutical compositions comprising fumarate esters suspended in liquid matrices are described. One embodiment described herein is a pharmaceutical composition comprising fumarate esters suspended in a lipid or lipophilic liquid with enhanced bioavailability.Type: GrantFiled: May 1, 2017Date of Patent: November 21, 2017Assignee: BANNER LIFE SCIENCES LLCInventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 9814692Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral controlled release pharmaceutical compositions comprising fumarate esters suspended in liquid matrices are described. One embodiment described herein is a pharmaceutical composition comprising fumarate esters suspended in a lipid or lipophilic liquid with enhanced bioavailability.Type: GrantFiled: December 21, 2016Date of Patent: November 14, 2017Assignee: Banner Life Sciences LLCInventors: Jason M. Vaughn, Justin R. Hughey, Tanesha Roberts, Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 9814691Abstract: Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In particular, oral pharmaceutical compositions comprising fumarate esters are described.Type: GrantFiled: November 22, 2016Date of Patent: November 14, 2017Assignee: BANNER LIFE SCIENCES LLCInventors: Tatyana Dyakonov, Sunil Agnihotri, Aqeel A. Fatmi
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Patent number: 9693978Abstract: Liquid and semi-solid pharmaceutical compositions, which can be administered in liquid form or can be used for preparing capsules, are described herein. The composition comprises the salt of one ore more active agents, polyethylene glycol, 0.2-1.0 mole equivalents of a de-ionizing agent per mole of active agent, and water. The pH of the composition is adjusted within the range of 2.5-7.5. The de-ionizing agent causes partial de-ionization (neutralization) of the salt of the active agent resulting in enhanced bioavailability of salts of weakly acidic, basic or amphoteric active agents as well as lesser amounts of polyethylene glycol (PEG) esters.Type: GrantFiled: December 22, 2015Date of Patent: July 4, 2017Assignee: Banner Life Sciences LLCInventors: Nachiappan Chidambaram, Aqeel Fatmi
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Patent number: 9693979Abstract: Described herein are oral pharmaceutical compositions comprising liquid dosage forms of sodium naproxen in soft gel capsules. In one embodiment, the pharmaceutical composition comprises sodium naproxen, 0.2-1.0 mole equivalents of a de-ionizing agent per mole of naproxen, polyethylene glycol, and one or more solubilizers such as propylene glycol, polyvinyl pyrrolidone or a combination thereof.Type: GrantFiled: May 20, 2016Date of Patent: July 4, 2017Assignee: Banner Life Sciences LLCInventors: Nachiappan Chidambaram, Aqeel A Fatmi