Abstract: Novel, sensitive and specific markers for diagnostics and monitoring of liver injuries, including, but not limited to ischemic liver damage, are provided. This includes identification of several enzymes of arginine/urea/nitric oxide cycle, sulfuration enzymes and spectrin breakdown related products, among others.
Type:
Grant
Filed:
January 12, 2010
Date of Patent:
November 1, 2011
Assignees:
University of Florida Research Foundation, Inc., Banyan Biomakers
Inventors:
Stanislav Svetlov, Ronald L. Hayes, Ka-Wang (Kevin) Wang, Monika Oli
Abstract: The present invention identifies biomarkers that are diagnostic of nerve cell injury and/or neuronal disorders. Detection of different biomarkers of the invention are also diagnostic of the degree of severity of nerve injury, the cell(s) involved in the injury, and the subcellular localization of the injury.
Type:
Application
Filed:
June 24, 2010
Publication date:
December 16, 2010
Applicants:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., BANYAN BIOMAKERS, INC.
Inventors:
KA-WANG (KEVIN) WANG, MING-CHENG LIU, MONIKA OLI