Patents Assigned to Barfold, Inc.
  • HIGH PRESSURE REFOLDING OF MONOCLONAL ANTIBODY AGGREGATES
    Publication number: 20120245329
    Abstract: Methods for refolding antibodies, particularly monoclonal antibodies, from aggregated and/or denatured preparations by subjecting the antibody preparation to high hydrostatic pressure are provided. Refolded preparations of antibodies produced by the methods described herein are also provided.
    Type: Application
    Filed: February 27, 2012
    Publication date: September 27, 2012
    Applicant: Barfold, Inc.
    Inventors: Matthew B. Seefeldt, Robert Nelson, Theodore W. Randolph, Lyndal K. Hesterberg