Abstract: An antisense oligonucleotide of 10 to 35 nucleotides in length that can hybridize with a region of the .alpha..sub.1 subunit of the SA-Cat channel gene DNA or mRNA is provided, together with pharmaceutical compositions containing and methods utilizing such antisense oligonucleotide.
Type:
Grant
Filed:
October 28, 1994
Date of Patent:
October 20, 1998
Assignee:
Barnes-Jewish Hopital
Inventors:
Keith A. Hruska, Peter A. Friedman, Elizabeth L. R. Barry, Randall L. Duncan