Patents Assigned to BARRY UNIVERSITY
  • Muscarinic agonists as non-steroidal and non-opioid analgesics and methods of use thereof
    Patent number: 11591323
    Abstract: Novel Gi/o-biased muscarinic agonists selectively activate only one specific signaling pathway and are novel pharmacophores for development of new painkillers (analgesics). Methods of making and using these agonists are also described. The muscarinic agonists are of the formula: or an analog, derivative or pharmaceutically acceptable salt thereof, wherein: R1=H or Me; R2=H, Me, Et, OMe, OEt, F, Cl, Br, I, or NO2; and R3=H, Me, Et, OMe, or CO2Me (R3 may be bonded to any carbon of the rings).
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: February 28, 2023
    Assignee: BARRY UNIVERSITY
    Inventor: John Boulos
  • Methods of treatment with nitric oxide at pressures greater than one atmosphere
    Patent number: 9364388
    Abstract: The present invention provides methods of treatment by delivering nitric oxide at a pressure greater than 1 atmosphere (atm) to a subject in need thereof. Thus, the present invention provides an improved method of treating the skin surface of a subject, and below the skin surface of a subject.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: June 14, 2016
    Assignee: BARRY UNIVERSITY
    Inventors: Frank J. McCaney, Jeffrey L. Jensen, Christopher C. Miller, Daniel Packert, Gerhild Packert, Alex Stenzler