Patents Assigned to BAS Medical, Inc.
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Publication number: 20060269892Abstract: Orthodontic methods comprise applying force to reposition teeth and administering a tissue remodeling and/or an angiogenic substance(s) to the periodontal tissue surrounding the teeth to be moved. The substance(s) may be delivered before, during, or after the teeth are moved, and the substance(s) may be selectively applied only to those teeth undergoing movement at any particular time. The substance(s) may be applied from the dental repositioning appliance or may be applied separately, either topically or by injection.Type: ApplicationFiled: April 27, 2005Publication date: November 30, 2006Applicant: BAS Medical, Inc.Inventors: Peter Breining, Dennis Stewart
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Publication number: 20060247163Abstract: The invention relates to the method for treatment, diagnosis and prevention of diseases related to fetal growth and placental insufficiency and comprises methods including inhibiting or increasing relaxin synthesis, relaxin receptor synthesis, relaxin binding to the relaxin receptor, and relaxin receptor activity. The invention also relates to screening assays to identify compounds that modulate relaxin and/or relaxin receptor activity. The invention further relates to gene therapy methods utilizing relaxin and relaxin-related sequences for the treatment and prevention of diseases related to fetal growth and placental insufficiency.Type: ApplicationFiled: May 2, 2005Publication date: November 2, 2006Applicant: BAS Medical, Inc.Inventor: Elaine Unemori
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Publication number: 20060052304Abstract: The invention relates to the discovery that relaxin receptors exist in bone and related sutures. As such, bone can be remodeled, repaired, removed or grown. Particularly, the invention pertains to a method for modifying a target bone by administering a relaxin compound which binds to relaxin receptors and by monitoring a change in the target bone. The invention further encompasses methods of modifying the height of a human subject.Type: ApplicationFiled: July 27, 2005Publication date: March 9, 2006Applicant: BAS Medical, Inc.Inventor: Dennis Stewart
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Patent number: 6984128Abstract: Orthodontic methods comprise applying force to reposition teeth and administering a tissue remodeling and/or an angiogenic substance(s) to the periodontal tissue surrounding the teeth to be moved. The substance(s) may be delivered before, during, or after the teeth are moved, and the substance(s) may be selectively applied only to those teeth undergoing movement at any particular time. The substance(s) may be applied from the dental repositioning appliance or may be applied separately, either topically or by injection.Type: GrantFiled: October 27, 2003Date of Patent: January 10, 2006Assignee: BAS Medical, Inc.Inventors: Peter M. Breining, Dennis R. Stewart
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Publication number: 20050238639Abstract: The present invention provides methods for increasing arterial compliance. The methods generally involve administering to an individual in need thereof an effective amount of relaxin. The present invention further provides methods of increasing arterial compliance in individuals who have Type 1 or Type 2 diabetes. The present invention further provides methods of increasing arterial compliance in perimenopausal, menopausal, and post-menopausal women. The present invention further provides methods of increasing arterial compliance in individuals who have or who are at risk of developing age-associated arterial stiffness.Type: ApplicationFiled: March 18, 2005Publication date: October 27, 2005Applicant: BAS Medical, Inc.Inventors: Kirk Conrad, Sanjeev Shroff
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Patent number: 6949506Abstract: The present invention relates to a relaxin-like factor, its derivatives or analogs, and uses thereof. The present invention further relates to compositions comprising a relaxin-like factor, its derivatives or analogs, and relaxin wherein such composition exhibits an additive or synergistic effect.Type: GrantFiled: April 30, 2001Date of Patent: September 27, 2005Assignee: BAS Medical, Inc.Inventors: Christian Schwabe, Elaine Unemori
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Publication number: 20050186526Abstract: The present invention provides methods for accelerating orthodontic tooth movement and for treating relapse. The orthodontic methods comprise applying force to reposition teeth and administering a tissue remodeling and/or an angiogenic substance to the periodontal tissue surrounding the teeth to be moved. The substance may be delivered before, during, or after the teeth are moved, and the substance may be selectively applied only to those teeth undergoing movement at any particular time. The substance may be applied from the dental repositioning appliance or may be applied separately, either locally or systemically. Orthodontic kits are also encompassed by the instant invention.Type: ApplicationFiled: December 16, 2004Publication date: August 25, 2005Applicant: BAS Medical, Inc.Inventors: Dennis Stewart, Peter Breining, Jonathan Nicozisis
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Patent number: 6780836Abstract: Relaxin is useful for promoting angiogenesis and the treatment of infections or ischemic wounds where the injury results from lack of oxygen due to poor circulation.Type: GrantFiled: February 8, 2001Date of Patent: August 24, 2004Assignee: BAS Medical, Inc.Inventor: Elaine Unemori
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Publication number: 20040115587Abstract: Orthodontic methods comprise applying force to reposition teeth and administering a tissue remodeling and/or an angiogenic substance(s) to the periodontal tissue surrounding the teeth to be moved. The substance(s) may be delivered before, during, or after the teeth are moved, and the substance(s) may be selectively applied only to those teeth undergoing movement at any particular time. The substance(s) may be applied from the dental repositioning appliance or may be applied separately, either topically or by injection.Type: ApplicationFiled: October 27, 2003Publication date: June 17, 2004Applicant: BAS Medical, Inc.Inventors: Peter M. Breining, Dennis R. Stewart