Abstract: The invention deals with the production of analogues of adenylyl (2'-5')adenylyl (2'-5')-9-(2,3-anhydro-.beta.-D-ribofuranosyl) adenine disodium salt by the phosphotriester method. The pharmaceutical composition prepared according to this invention inhibits the host-vs.-graft response.
Type:
Grant
Filed:
August 29, 1994
Date of Patent:
November 5, 1996
Assignee:
Basco, Ltd.
Inventors:
Zenovy Tkachuk, Eugeny Kvasyuk, Gennady Matsuka, Igor Mikhailopulo