Abstract: The present invention relates to a process for preparing optically active aldehydes or ketones which have from 3 to 25 carbon atoms and at least one racemizable stereocenter by catalytic dehydrogenation of the corresponding optically active primary or secondary alcohols in the gas phase in the presence of a catalyst.
Type:
Grant
Filed:
March 4, 2005
Date of Patent:
December 23, 2008
Assignee:
BASF AG
Inventors:
Thorsten Johann, Oliver Löber, Eike Johannes Bergner, Klaus Ebel, Klaus Harth, Christian Walsdorff
Abstract: The present invention describes a Pd-catalyst which further contains La, Ti, Nb, K or Si. The Pd-catalyst has a high ethylene selectivity even after a low temperature reduction in the selective hydrogenation of acetylene to ethylene. The invention also relates to the production of the catalyst. A catalyst of the invention consists essentially of 0.05 to 2.0% by weight, based on the supported catalyst, of palladium and one or two metals chosen form the group consisting of lanthanum, niobium, titanium, potassium and silicon. The catalyst can be prepared by the following procedure. (1) Impregnating a support in aqueous solution of tetra amine palladium hydroxide, followed by drying and calcination; (2) The second and, if necessary, a third metal is impregnated by impregnating the Pd-catalyst in the solution of the metal precursor followed by drying and calcination; (3) The catalyst according to step (2) is then reduced in hydrogen at 200° C. to 600° C. for 1 to 5 hours.
Type:
Grant
Filed:
March 26, 2004
Date of Patent:
November 18, 2008
Assignee:
BASF AG
Inventors:
Sang Heup Moon, Woo Jae Kim, Jung Hwa Kang, In Young Ahn
Abstract: Isolated polypeptide sequence having the sequence of SEQ ID NO:1 or muteins thereof having the ability to bind cAMP and repress the expression of the aceB gene of C. glutamicum and which can be obtained from SEQ ID NO:1 by inserting, deleting or substituting up to 20% of the amino acids.
Type:
Application
Filed:
February 8, 2007
Publication date:
November 13, 2008
Applicant:
BASF AG
Inventors:
Corinna Klopprogge, Oskar Zelder, Burkhard Kroger, Hartwig Schroder, Stefan Hafner, Heung-Shick Lee
Abstract: The invention relates to a process for preparing enantiomerically pure alcohol of the formula 1, which comprises (i) reducing the ketone of the formula 3to the racemic alcohol of the formula 4, (ii) enantioselectively acylating the racemic alcohol of the formula 4 with succinic anhydride in the presence of a lipase to give the succinic semiester of the formula 7, (iii) separating off the succinic semiester of the formula 7 from the unreacted enantiomer of the formula 4, (iv) reacting the enantiomerically pure alcohol of the formula 4 with methylamine to give the enantiomerically pure alcohol of the formula 1.
Abstract: The invention relates to methods and compositions for analyzing plant acetohydroxy acid synthase large subunit (AHASL) genes. In particular, the invention relates to methods for the detection of wild-type AHASL alleles and mutant AHASL alleles that encode imidazolinone-tolerant AHASL proteins. The methods involve the use of PCR amplification and novel compositions comprising allele-specific and gene-specific primers to detect the presence of mutant and/or wild-type alleles present at the individual AHASL genes of a plant. Specifically, the methods and compositions are useful for analyzing the three AHASL genes of Triticum aestivum and the two AHASL genes of Triticum turgidum ssp. durum.
Type:
Grant
Filed:
March 22, 2004
Date of Patent:
October 7, 2008
Assignee:
BASF AG
Inventors:
Chengyan Zhao, Robert Ascenzi, Bijay K. Singh
Abstract: The invention relates to a method for producing an amino acid comprising culturing a microorganism of the genus Corynebacterium or Brevibacterium wherein said microorganism is partially or completely deficient in at least one of the gene loci of the group which is formed by otsAB, treZ and treS, and subsequent isolation of the amino acid from the culture medium.
Type:
Application
Filed:
January 28, 2008
Publication date:
July 10, 2008
Applicant:
BASF AG
Inventors:
Corinna Klopprogge, Oskar Zelder, Burkhard Kroger, Hartwig Schroder, Stefan Hafner, Wolfgang Liebl
Abstract: The invention relates to a process for enriching trehalose from solutions, in which the enrichment is performed using an adsorbent, in which the adsorbent is an aluminosilicate. Preferably, the aluminosilicate is a zeolite. The invention further relates to the enrichment and purification of trehalose from fermentation broths, in particular as a coupled product of production by fermentation of other products of value.
Type:
Application
Filed:
March 18, 2005
Publication date:
May 8, 2008
Applicant:
BASF AG
Inventors:
Matthias Boy, Markus Pompejus, Daniela Klein, Martin Volkert, James Reuben Brown
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
Type:
Grant
Filed:
November 3, 2006
Date of Patent:
April 8, 2008
Assignee:
BASF AG
Inventors:
Oskar Zelder, Markus Pompejus, Hartwig Schröder, Burkhard Kröger, Corinna Klopprogge, Gregor Haberhauer
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of the genetically improved microorganisms.
Type:
Grant
Filed:
November 8, 2006
Date of Patent:
April 8, 2008
Assignee:
BASF AG
Inventors:
Oskar Zelder, Markus Pompejus, Hartwig Schröder, Burkhard Kröger, Corinna Klopprogge, Gregor Haberhauer
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
Type:
Grant
Filed:
November 17, 2006
Date of Patent:
April 8, 2008
Assignee:
BASF AG
Inventors:
Oskar Zelder, Markus Pompejus, Hartwig Schröder, Burkhard Kröger, Corinna Klopprogge, Gregor Haberhauer
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
Type:
Grant
Filed:
November 21, 2006
Date of Patent:
April 8, 2008
Assignee:
BASF AG
Inventors:
Oskar Zelder, Markus Pompejus, Hartwig Schröder, Burkhard Kröger, Corinna Klopprogge, Gregor Haberhauer
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
Type:
Grant
Filed:
November 8, 2006
Date of Patent:
April 8, 2008
Assignee:
BASF AG
Inventors:
Oskar Zelder, Markus Pompejus, Hartwig Schröder, Burkhard Kröger, Corinna Klopprogge, Gregor Haberhauer
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
Type:
Grant
Filed:
November 3, 2006
Date of Patent:
March 4, 2008
Assignee:
BASF AG
Inventors:
Oskar Zelder, Markus Pompejus, Hartwig Schröder, Burkhard Kröger, Corinna Klopprogge, Gregor Haberhauer
Abstract: The invention relates to novel nucleic acid molecules, to the use thereof for constructing genetically improved microorganisms and to methods for preparing fine chemicals, in particular amino acids, with the aid of said genetically improved microorganisms.
Type:
Grant
Filed:
November 2, 2006
Date of Patent:
January 29, 2008
Assignee:
BASF AG
Inventors:
Oskar Zelder, Markus Pompejus, Hartwig Schröder, Burkhard Kröger, Corinna Klopprogge, Gregor Haberhauer
Abstract: A method of forming a composition comprising adding at least one first compound that is at least one of an alkali metal salt, an ammonium salt, an alkali metal hydroxide, or an ammonium hydroxide and at least one second compound that is at least one of a Group IIA salt, a Group IIIA salt, a Group IIIB salt, a copper salt, a zinc salt, a cadmium salt, a manganese salt, an iron salt, a cobalt salt, or a nickel salt to a latex. This method allows for the formation of nanoparticles in the composition.
Abstract: Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing PTS nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated PTS proteins, mutated PTS proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of PTS genes in this organism.
Type:
Application
Filed:
August 17, 2006
Publication date:
May 17, 2007
Applicant:
BASF AG
Inventors:
Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer
Abstract: Isolated nucleic acid molecules, designated MCP nucleic acid molecules, which encode novel MCP proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCP nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MCP proteins, mutated MCP proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MCP genes in this organism.
Type:
Application
Filed:
August 17, 2006
Publication date:
May 3, 2007
Applicant:
BASF AG
Inventors:
Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer
Abstract: Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SRT proteins, mutated SRT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SRT genes in this organism.
Type:
Application
Filed:
August 22, 2006
Publication date:
April 5, 2007
Applicant:
BASF AG
Inventors:
Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer, Heung-Shick Lee, Hyung-Joon Kim
Abstract: Isolated nucleic acid molecules, designated SRT nucleic acid molecules, which encode novel SRT proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing SRT nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated SRT proteins, mutated SRT proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of SRT genes in this organism.
Type:
Application
Filed:
August 22, 2006
Publication date:
March 15, 2007
Applicant:
BASF AG
Inventors:
Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer, Heung-Shick Lee, Hyung-Joon Kim
Abstract: Isolated nucleic acid molecules, designated MR nucleic acid molecules, which encode novel MR proteins from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MR nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides isolated MR proteins, mutated MR proteins, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from C. glutamicum based on genetic engineering of MR genes in this organism.
Type:
Application
Filed:
August 21, 2006
Publication date:
March 15, 2007
Applicant:
BASF AG
Inventors:
Markus Pompejus, Burkhard Kroger, Hartwig Schroder, Oskar Zelder, Gregor Haberhauer