Patents Assigned to Basilea Pharmaceutica AG, A Swiss Company
  • Patent number: 6872836
    Abstract: The invention is concerned with a process for the manufacture of 3-amino-pyrrolidine derivatives of the formula wherein R1 signifies hydrogen or an amino protecting group; Z signifies hydrogen or an amino protecting group; and * represents a center of chirality. 3-Amino-pyrrolidine derivatives, especially optically active 3-amino-pyrrolidine derivatives, are intermediates for the production of agrochemicals and of pharmaceutically active substances such as, for example, of vinylpyrrolidinone-cephalosporin derivatives.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: March 29, 2005
    Assignee: Basilea Pharmaceutica AG, A Swiss Company
    Inventors: Marc Muller, Milan Soukup
  • Patent number: 6300353
    Abstract: Azole derivatives of the formula I wherein R14, R15 are each independently hydrogen or fluorine, T is a group of the formula: wherein R9 is pyrrolidinyl or a group A—NH—B—, A is hydrogen or straight-chain or branched C1-C5 alkyl; B is straight-chain or branched C1-C4 alkylene, —CH2—CONH—CH2 or —CH2CH2CH2—CH(NH2); and X− is a pharmaceutically acceptable anion; and pharmaceutically acceptable salts of said compounds, and hydrates and solvates of the compounds of formula I and the salts thereof can be used in the production of medicaments for treating fungal infections and mycoses.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: October 9, 2001
    Assignee: Basilea Pharmaceutica AG, a Swiss Company
    Inventors: Tadakatsu Hayase, Shigeyasu Ichihara, Yoshiaki Isshiki, Pingli Liu, Jun Ohwada, Toshiya Sakai, Nobuo Shimma, Masao Tsukazaki, Isao Umeda, Toshikazu Yamazaki