Abstract: A method of calculating clinical performance of an ophthalmic optical correction using simulation by imaging a series of objects of different sizes by each of a plurality of eye optical systems, each of the eye optical systems including the ophthalmic optical correction, the method comprising A.) at an object distance, calculating a set of indicia of image quality, each indicium of the set of indicia corresponding to an object in the series of objects when it is imaged by a given one of the plurality of eye optical systems, B.) at the object distance, comparing the set of indicia to a threshold to determine a just-discernable object size for the given one of the plurality of eye optical systems, and C.) repeating steps A and B for each eye optical system in the plurality of eye optical systems.
Type:
Application
Filed:
November 7, 2012
Publication date:
May 8, 2014
Applicant:
Bausch & Lomb Incorporated
Inventors:
Amanda C. Kingston, Paul D. Ludington, Richard Potvin
Abstract: A combination of an irrigation sleeve 20 and a phacoemulsification needle 22. The irrigation sleeve 20 has a proximal end 32 and a distal end 30, the proximal end for attachment to a surgical handpiece. The phacoemulsification needle 22 has a proximal end 26, a distal end 24, and a lumen 38 spanning a length of the needle 22 from the proximal end 26 to the distal end 24. The needle proximal end 26 is for connection to the surgical handpiece, and the needle 22 has structure 44 proximate the needle distal end 24 for retaining the sleeve distal end 30 near the needle distal end 24.
Abstract: A contact lens such as a toric contact lens having hybrid stabilization features is disclosed. The lens includes a lens edge, a vertical meridian, a horizontal meridian, a superior region, an inferior region, an optical zone, a prism ballast zone and a peri ballast zone, wherein the contact lens has a dimple zone disposed between the optical zone and the lens edge and is centered on the inferior vertical meridian.
Abstract: A set of toric contact lenses, where each lens in the set includes a posterior surface and an anterior surface. For each lens in the set, at least one of the posterior and anterior surfaces includes a toric optical zone. Each lens in the set has a common effective base curve and a common overall diameter, but a different cylindrical correction. Lenses in the set have a peripheral zone and a blend zone disposed between the peripheral zone and the toric optical zone. In lenses of such a set, the width of said blend zone at a common location on at least two of the lenses are selected to be different so that the thicknesses at a common position on the lenses are substantially the same for all lenses in the set.
Abstract: In a first aspect, the invention provides an IOL having an optic with a peripheral section including one or more visually observable markers formed on the optic peripheral section and located within the visually observable zone of a surgeon viewing the IOL in the implanted condition through the pupil. In a second aspect of the invention, the IOL peripheral section includes an edge provided with a plunger engagement segment configured to inhibit off-axis movement of a plunger tip when engaged therewith.
Abstract: An ophthalmic surgical device 10 includes a housing 12 having a distal end 14 and a proximal end 16. A cannula 18 is attached to the housing distal end 14 and has a distal tip 20 with at least one port 22 in communication with a lumen 19 extending through the cannula 18 and in communication with an aspiration path 24 in the housing 12. A vibration source 26 is held within the housing 12 for vibrating the distal tip 20 for assisting in vitreous and other tissue removal. An aspiration source 152 connected to the aspiration path 24 for applying a negative pressure to the lumen 19 and the at least one port 22 for removing fluids and the vitreous and other tissue from the eye. The vibration source 26 and the aspiration source 152 together create a periodic bi-directional flow of tissue through the port 22 without creating cavitation externally of the distal tip 20.
Type:
Application
Filed:
September 6, 2013
Publication date:
March 13, 2014
Applicant:
BAUSCH & LOMB INCORPORATED
Inventors:
Brian D. McCary, Toh Seng Goh, James Taylor Perkins
Abstract: Brush copolymers containing (a) monomeric units derived from an ethylenically unsaturated-containing monomer containing one or more boronic acid moieties; and (b) monomeric units derived from an ethylenically unsaturated-containing macromonomer having hydrophilic units and boronic acid units are disclosed.
Abstract: Ophthalmic composition that includes 0.05% w/v to 2% w/v diglycine or a salt thereof; 0.01 ppm to 3 ppm poly(hexamethylene biguanide); 1 ppm to 10 ppm ?-[4-tris(2-hydroxyethyl)ammonium chloride-2-butenyl]poly[1-dimethylammonium chloride-2-butenyl]-?-tris(2-hydroxyethyl)ammonium chloride; and 0.1% w/v to 2% w/v of one or more boron buffering compounds.
Type:
Grant
Filed:
February 6, 2012
Date of Patent:
March 4, 2014
Assignee:
Bausch & Lomb Incorporated
Inventors:
Susan E. Burke, Erning Xia, Catherine A. Scheuer, Srini Venkatesh
Abstract: Apparatus and methods for injection molding intraocular lenses includes an embodiment having first and second runners extending into first and second optic cavities of a mold configured to make a dual optic lens device.
Type:
Grant
Filed:
October 14, 2011
Date of Patent:
March 4, 2014
Assignee:
Bausch & Lomb Incorporated
Inventors:
Anita M. Graney, Graham W. Biddle, Thomas Lodadio, William J. Appleton
Abstract: Provided herein is a polymerized product formed of a polymerized monomer mixture comprising intentionally added water and at least one hydrophilic monomer wherein the monomer mix does not contain any silicon containing materials. The polymerized monomer mixture of the invention herein is useful in many biomaterial applications. Especially preferred is the use of the biomaterial as a hydrogel contact lens.
Type:
Application
Filed:
August 2, 2013
Publication date:
February 6, 2014
Applicant:
Bausch & Lomb Incorporated
Inventors:
Ritu Shrestha, Alok K. Awasthi, Lynn F. Atwater, Jay Friedrich Kunzler, Richard Fanqing Meng
Abstract: A polymorph of brimonidine pamoate having the formula exhibits characteristics disclosed herein. The polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocular pressure or in the neuroprotection of components of a neurological tissue to prevent progressive degeneration of such components. In particular, such a composition, device, or implant can be used to provide neuroprotection to cells and components of the optic nerve system.
Type:
Grant
Filed:
March 14, 2013
Date of Patent:
January 28, 2014
Assignee:
Bausch & Lomb Incorporated
Inventors:
Hongna Wang, Stephen R. Davio, Gregory L. McIntire, Michael Hall, Shazad Suchit, Jon Summersett, Brent Whitehead
Abstract: A polymorph of brimonidine pamoate having the formula exhibits characteristics disclosed herein. The polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocular pressure or in the neuroprotection of components of a neurological tissue to prevent progressive degeneration of such components. In particular, such a composition, device, or implant can be used to provide neuroprotection to cells and components of the optic nerve system.
Type:
Grant
Filed:
March 14, 2013
Date of Patent:
January 28, 2014
Assignee:
Bausch & Lomb Incorporated
Inventors:
Hongna Wang, Stephen R. Davio, Gregory L. McIntire, Michael Hall, Shazad Suchit, Jon Summersett, Brent Whitehead
Abstract: Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a brush copolymer comprising (a) monomeric units derived from an ethylenically unsaturated monomer containing one or more boronic acid moieties; and (b) monomeric units derived from an ethylenically unsaturated-containing hydrophilic macromonomer.
Type:
Grant
Filed:
December 18, 2009
Date of Patent:
January 21, 2014
Assignee:
Bausch & Lomb Incorporated
Inventors:
David Paul Vanderbilt, Paul L. Valint, Jr.
Abstract: An ophthalmic composition comprising one or more antimicrobial components and a dipeptide. The dipeptide comprises a glycine moiety and another amino acid moiety other than glycine. The ophthalmic compositions include contact lens care solutions for cleaning and disinfecting contact lenses.
Abstract: A multi-element accommodating intraocular lens (AIOL) having a first anterior translation member and a first posterior translation member coupled together to form a first bias element. The first posterior translation member has a greater resistance to bending than the first anterior translation member. The first posterior translation member has a greater thickness than the first anterior translation member.
Abstract: A daily nutritional or dietary supplement composition that strengthens and promotes retinal health through the prevention, stabilization, reversal and/or treatment of visual acuity loss by reducing the risk of developing late stage or advanced age-related macular degeneration in persons with early age-related macular degeneration. The ingredients of the daily nutritional or dietary supplement composition include vitamin C, vitamin E, lutein, zinc and copper. The ingredients are preferably provided in a tablet form suitable for oral ingestion.
Type:
Grant
Filed:
January 13, 2005
Date of Patent:
December 10, 2013
Assignee:
Bausch & Lomb Incorporated
Inventors:
Stephen Paul Bartels, Cara Larraine Baustian, George Edwin Bunce, Leon Ellenbogen, Frederick L. Ferris, III, Jin Kinoshita, James Cecil Smith, Jr., David A. Souerwine
Abstract: An IOL injector body including an injector body segment defining a portion of a lumen, and a first loading chamber component coupled to the injector body segments and a second loading chamber component hingedly coupled to the first loading chamber component. The second loading chamber component is capable of rotating about an axis that is parallel to the lumen. An IOL vial including a vial base and an injector guide rotatably mounted in said base, whereby an injector can be inserted along the injector guide and rotated such that a folded IOL can be obtained in the injector. A method of loading an IOL injector with an IOL the method that comprises inserting the IOL injector body into a vial and rotating the IOL injector body relative to the vial to obtain the IOL in the IOL injector body.
Abstract: Disclosed herein is a molecular crystal form of (R)-(+)-7-(3-amino-2,3,4,5,6,7-hexahydro-1H-azepin-1-yl)-1-cyclopropyl-8-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid. The molecular crystal is characterized by at least one of: (a) an X-ray powder diffraction (“XRPD”) spectrum that comprises peaks at 2? angles of 10.6, 15, 19.7, 21.1, and 22°±0.2°; (b) a DSC melting peak at 288° C.; (c) a 13C NMR spectrum having peaks at 23.3, 27.7, 41.1, 54.5, 116.6, and 153.5 ppm; and (d) pKa values of 5.65 and 9.91. The compound belongs to the class of fluoroquinolones and is useful as an antibacterial agent.