Patents Assigned to Bausch & Lomb
  • Besifloxacin ophthalmic composition for the treatment or control of infection
    Patent number: 8415342
    Abstract: A composition comprises besifloxacin in an amount effective for treating or controlling an infection caused by an antibiotic-resistant bacterium. Such a composition can be administered to a subject for the treatment or control of bacterial conjunctivitis caused bay an antibiotic-resistant bacterium.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: April 9, 2013
    Assignee: Bausch & Lomb Incorporated
    Inventors: Praveen Tyle, Pramod Kumar Gupta, Susan E. Norton, Lynne Brunner, Joseph Blondeau
  • Pneumatic surgical instrument detection system
    Patent number: 8403917
    Abstract: A system detects whether a pneumatic surgical instrument is attached to a surgical system. A drive valve has an input for connection to a source of pressurized air, an output for connection to the surgical instrument, and an exhaust for exhausting pressurized air during operation of the surgical instrument. A pressure transducer in communication with the exhaust senses a pressure profile of air flow from the exhaust. A first sensed pressure profile indicates that the surgical instrument is connected to the output and a second sensed pressure profile indicates that the surgical instrument is not connected to the output. A detection circuit connected to an output of the pressure transducer detects whether the surgical instrument is attached to the surgical system based on the sensed pressure profile.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: March 26, 2013
    Assignee: Bausch & Lomb Incorporated
    Inventors: Allen W. Skinner, James T. Perkins, David W. Hertweck
  • High water content ophthalmic devices
    Patent number: 8389597
    Abstract: An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: March 5, 2013
    Assignee: Bausch & Lomb Incorporated
    Inventors: Richard I. Blackwell, Joseph C. Salamone, Jay F. Kunzler
  • Renewable polymeric lens coating
    Patent number: 8377126
    Abstract: Disclosed are biomedical devices having a hydrophilic coating on a portion of a surface thereof, the biomedical device comprising: (a) a biomedical device obtained from a polymerization product of a monomeric mixture comprising (i) a polymerizable monomer containing a boronic acid moiety and an electron withdrawing moiety; and (ii) a biomedical device-forming comonomer; and (b) a hydrophilic reactive polymer having complementary reactive functionalities along the polymer chain, wherein the complementary reactive functionalities along the polymer chain of the hydrophilic reactive polymer of (b) bind with the boronic acid moieties of the biomedical device of (a), thereby producing a biocompatible coating which can be removed and re-applied to restore the surface properties of the biomedical device to substantially as-new condition. Methods for treating the biomedical device are also disclosed.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: February 19, 2013
    Assignee: Bausch & Lomb Incorporated
    Inventors: Joseph A. McGee, David Paul Vanderbilt, Paul L. Valint, Jr.
  • Polymerizable surfactants and their use as device forming comonomers
    Patent number: 8377464
    Abstract: This invention describes the use of polymerizable surfactants as comonomers in forming ophthalmic devices such as contact lenses, intraocular lenses, corneal implants, etc.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: February 19, 2013
    Assignee: Bausch & Lomb Incorporated
    Inventors: Jeffrey G. Linhardt, Daniel M. Ammon, Jr., Joseph C. Salamone, Daniel J. Hook
  • Polymeric quaternium compounds
    Patent number: 8349303
    Abstract: A topical pharmaceutical composition comprising a pharmaceutical active and a polymer of general formula I or general formula II wherein Ck is a saturated or unsaturated, five, six or seven-membered ring; R is a C1-C3alkyl; n is 1, 2, 3, 4 or 5 and m provides a number average molecular weight of the polymer of from 2000 to 80,000.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: January 8, 2013
    Assignee: Bausch & Lomb Incorporated
    Inventors: Eric Phillips, Jay F. Kunzler, Alok Kumar Awasthi
  • Crosslink agents and dual radical cure polymer
    Patent number: 8349912
    Abstract: Crosslink agents used to copolymerize at least one hydrophilic monomer with at least one lens monomer typically used to prepare polymeric materials for ophthalmic lenses. The crosslink agents have a relatively high selectivity for the hydrophilic monomer and limited reactivity with the crosslink agent used to polymerize the lens monomer. Accordingly, the invention is also directed to a hydrophilic crosslinked polymer that comprises at least two monomeric units and at least two different crosslink units. The use of the dual crosslink system provides an improved means to control the final chemical, physical and structural characteristics of the resulting polymer.
    Type: Grant
    Filed: September 12, 2011
    Date of Patent: January 8, 2013
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ivan M. Nunez, Joseph A. McGee, David E. Seelye
  • Optical material and method for modifying the refractive index
    Patent number: 8337553
    Abstract: The invention is directed to an optical device comprising refractive optical structures, wherein the refractive structures are characterized by a change in refractive index, exhibit little or no scattering loss, and exhibit no significant differences in the Raman spectrum with respect to the non-irradiated optical, polymeric material.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: December 25, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra M. Jani, Candido D. Pinto
  • Biomedical devices
    Patent number: 8337551
    Abstract: Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer which has only one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (RAFT) agent; and (b) one or more biomedical device-forming comonomers are disclosed.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: December 25, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: Jeffrey G. Linhardt, Ivan M. Nunez, Joseph A. McGee, Jennifer Hunt, Michele Alton, Drazen Pavlovic, Devon A. Shipp
  • Phacoemulsification cannula with improved purchase
    Patent number: 8333741
    Abstract: A phacoemulsification cannula 10 includes a hub 12 for engagement with an ophthalmic surgical instrument. An elongated needle 14 having a proximal end 16 is attached to the hub 12. The cannula 10 has an aspiration lumen 20 spanning a majority of a length of a needle 14 from the proximal end towards a distal end 18. A venturi lumen 22 is formed in the needle adjacent the distal end. The venturi lumen 22 is in communication with the aspiration lumen 20 so that fluid and tissue may be aspirated through the venturi lumen 22 and the aspiration lumen 20.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: December 18, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: Mario P. Gomez, Iidefonso Gonzalez, Dimas Joel Rullan
  • Compositions and methods for treating, reducing, ameliorating, or preventing infections
    Patent number: 8334283
    Abstract: Compositions for treating, reducing, ameliorating, or preventing infections comprise a fluoroquinolone having Formulae I-VIII and an additional anti-infective agent. Methods for treating, reducing, ameliorating, or preventing such infection use such compositions. Such compositions and methods can be effective against mixed types of pathogens including certain antibiotic-resistant microbial pathogens found in such infections.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: December 18, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: Praveen Tyle, Erning Xia, Hongna Wang, Susan E. Norton, Pramod Kumar Gupta, Keith W. Ward, Lynne Brunner
  • Sterilization of intraocular lenses
    Patent number: 8329097
    Abstract: A packaged, sterilized intraocular lens prepared by a process comprising providing a hydrophobic acrylic, or low water acrylic, intraocular lens and positioning the acrylic lens in a lens enclosure with an aqueous solution to provide a lens package. The lens package is then heated to a temperature sufficient for sterilization, however, the heating of the lens package must begin before the acrylic lens reaches an equilibrated, hydrated state following contact of the lens with the aqueous solution. The resulting sterilized acrylic intraocular lens will have less than sixty percent of total volume of disc-like features, or less than forty percent of total volume of water vacuoles, after 60 days following sterilization compared to an acrylic lens of the same composition, which was sterilized under the same conditions, but in an equilibrated, hydrated state.
    Type: Grant
    Filed: December 7, 2009
    Date of Patent: December 11, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventor: Jay F. Kunzler
  • System for operating and controlling a pneumatically driven vitrectomy probe
    Patent number: 8328835
    Abstract: A pneumatically driven vitrectomy probe system includes a movable member disposed within a cylinder to define an enclosed pressure chamber, which has an inlet and an outlet. A pressure transducer senses the pressure level within the enclosed pressure chamber, and a valve communicates pressurized air to the inlet of the enclosed pressure chamber based on the pressure level. A displacement device coupled to the movable member extends and retracts the movable member within the enclosed pressure chamber, to respectively increase and decrease the pressure level of pressurized air communicated via the chamber outlet. The pressurized air is communicated to enclosed volume within a pneumatically activated vitrectomy probe, which includes a hollow inner cutting member disposed within the hollow outer member.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: December 11, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: James T. Perkins, Brian D. McCary
  • Methods of designing lenses having selected depths of field
    Patent number: 8331048
    Abstract: A method of designing a lens having an image plane corresponding to an object located at infinity, comprising optimizing the lens by specifying quantities of light to pass through each of a plurality of the apertures. A method of designing a lens, comprising defining a plurality of objects each at a corresponding object location, at least one of the objects being a virtual object of the lens, and optimizing the lens by specifying for each of the objects a quantity of light to pass through a corresponding aperture disposed in an image space of the lens.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: December 11, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventor: Paul D. Ludington
  • Ophthalmic compositions containing diglycine
    Patent number: 8324171
    Abstract: Ophthalmic composition that includes 0.05% w/v to 2% w/v diglycine or a salt thereof; 1.0 ppm to 8.5 ppm alexidine, and 0.1% w/v to 2% w/v of one or more boron buffering compounds.
    Type: Grant
    Filed: February 6, 2012
    Date of Patent: December 4, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: Susan E. Burke, Erning Xia, Catherine A. Scheuer, Srini Venkatesh
  • Ophthalmic surgical cassette and system
    Patent number: 8303542
    Abstract: A cassette 74 for use with an ophthalmic surgical pump 16 for collecting aspirant fluid and tissue from a patient's eye includes a rigid walled container 18 having an interior volume 42. At least one tapered alignment slot 20 is formed in a side wall of the container 18 and extends from a back wall 24 towards a front wall 26. An irrigation and aspiration manifold base 50 is removeably attached to the container 18. An aspiration path 46 is formed within the container 18 for receiving the aspiration fluid and the tissue from the eye and directing the flow of fluid towards a front half of the container 18 before the fluid and tissue collects within a majority of the interior volume 42 of the container 18. A fluid level indicator 34 is formed on a wall 22 of the container 18, such that an associated photo-detector 86 of the pump 16 may determine a level of fluid in the container 18.
    Type: Grant
    Filed: June 5, 2007
    Date of Patent: November 6, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: Jonathan T. Walter, Mike Askew
  • Methods and apparatus for facilitating elimination of ambient light from an image
    Patent number: 8295635
    Abstract: An apparatus for facilitating elimination of ambient light from an image of an object, comprising an illumination apparatus adapted to sequentially illuminate the object using multiple lighting arrangements, an image sensor. The apparatus adapted to form on the image sensor (i) a first image of the object using a first illumination arrangement, (ii) a second image of the object using a second illumination arrangement, and (iii) a dark image of the object without illumination.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: October 23, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: Jeffrey B. McBeth, Lloyd G. Allred, Ning Zhang, Barry T. Eagan
  • Illumination device and method of use for ophthalmic surgery
    Patent number: 8287525
    Abstract: An illumination device for use in an ophthalmic surgical apparatus, the illumination device including a fiber optic having a proximal end and a connector coupled to the fiber optic. The connector includes one or more of (1) a datum surface disposed a predetermined distance from the proximal end to position the proximal end at a predetermined location within the surgical apparatus, (2) a shutter actuation surface configured and arranged to open a shutter in the surgical apparatus when the connector is being connected to the surgical apparatus, and (3) a visual indicator position to provides a visual indication that the connector is fully inserted into the surgical apparatus. The illumination device may be in a combination with an ophthalmic surgical apparatus.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: October 16, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: David John Stocks, Simon Roderick Grover, Mike Nelson
  • Sterile hyaluronic acid solutions
    Patent number: 8283463
    Abstract: A process for sterilizing a solution comprising hyaluronic acid. The process comprises providing an aqueous solution of hyaluronic acid with a weight average molecular weight from 0.6 MDa to 3.6 MDa, and the concentration of the hyaluronic acid is from 0.04% to 0.8% by weight. The aqueous solution also has an ionic strength equivalent to an aqueous concentration of sodium chloride from 3% to 30% by weight. Once the aqueous, high salt, hyaluronic acid solution is prepared the solution is maintained at a temperature from 40° C. to 80° C. for at least 1 hour and not longer than six days. Following the heat treatment step, the aqueous solution is filtered through a sterilization filter medium to provide a sterilized high salt, hyaluronic acid solution.
    Type: Grant
    Filed: February 9, 2010
    Date of Patent: October 9, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventors: X. Michael Liu, David J. Heiler, Thomas Menzel, Abbie Brongo, Susan E. Burke, Karl Cummins
  • Contact lens
    Patent number: D671580
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: November 27, 2012
    Assignee: Bausch & Lomb Incorporated
    Inventor: Kevin J. Fahy