Abstract: An in-line set filter for parenteral solution sets and the like which comprises a tubular housing having first and second ends. A bundle of filter tubes is positioned within the housing, the filter tubes preferably being folded so that all ends of the filter tubes occupy a single zone in communication with the first housing end. The zone is filled with potting compound with the filter tube ends communicating through the potting compound and open to the exterior. A flow access port is laterally positioned in a side wall between the second end and the potting compound but closer to the potting compound. The second end defines an open aperture occluded by a porous hydrophobic filter to permit venting while preventing loss of aqueous liquid.

Abstract: A disposable self-locking injection site can be clamped onto tubing anywhere along the line. The injection site includes a tubular barrel having two sections integrally hinged together with snap-fitting coupler parts which lock the sections together in a closed position about the line. The tubular barrel is shaped to define an interior recess communicating with at least one needle-receiving aperture. The interior recess snugly receives a self-sealing needle-penetrable resilient member or sleeve for cushioning and fluidly sealing the line so as to permit fluid-tight injection and withdrawal of a needle.

Abstract: A support member for use in a coil dialyzer to support an elongated, tubularly-shaped, semipermeable membrane is disclosed herein. The member is embossed and has generally angularly extending parallel ribs on both sides of the web. The ribs are arranged so that on each side there are high ribs and low ribs positioned between said high ribs. The ribs on opposite sides overlap in such a manner to form an angle varying between 60.degree. and 140.degree.. Furthermore, the ribs are arranged in a pattern wherein there are four short ribs positioned between adjacent pairs of high ribs.

Abstract: A connector system for use in a dialyzer is disclosed herein for connecting an external fluid conduit to a tubularly-shaped, semipermeable membrane. The system protects the membrane from forces imposed on the conduit. The system includes a jack member, which is secured within the dialyzer and has a passageway, which at one end is connected to the conduit and which at the other end is connected to a button-type connector which provides communication between the passageway and the semipermeable membrane. The button connector includes a cap and a barrel and has a passageway extending through the cap and barrel.

Abstract: A variable capacity reservoir assembly for use in a blood oxygenation system which includes a collapsible reservoir and an elongated unitary clamp. The reservoir is of fluid-impermeable flexible material and includes an expandable portion capable of holding a predetermined maximum volume of blood. The reservoir also includes one main blood inlet and one main blood outlet. The clamp is bifurcated and slidably engages the reservoir, preferably between the inlet and the outlet and grasps the expandable portion so as to control the expansion thereof and thereby control its blood holding capacity.

Abstract: A method of fractionating coagulation factor-depleted blood serum or plasma by selective precipitation with block copolymers of ethylene oxide and polyoxypropylene polymer to provide immunoglobulin preparations, albumin-containing fractions and organ perfusates.

Abstract: A diffusion device is disclosed made from a stack of pairs of semi-permeable membrane walls and plate members positioned between adjacent membrane wall pairs for support thereof. Flow conduits extend transversely of the stack in communication with flow passages between the membranes or between each membrane and each adjacent plate member. In accordance with this invention, staging means are provided for directing fluid in the flow passages successively along different membrane wall pairs to lengthen the fluid path of flow for improved diffusion. The staging means comprises an occluding member in the transversely extending flow conduits, positioned to redirect flow received from along one membrane wall pair along another membrane wall pair.

Abstract: A coil dialyzer is disclosed herein which includes a hollow core assembly to which an inlet blood conduit is connected. A semipermeable membrane and a support member are connected to the core and wound about the core. An outlet jack assembly is connected to the other end of the membrane and a blood outlet conduit is connected to the outlet jack. This assembly is positioned within a housing having both a top cap and a bottom cap. Incoming blood flow is directed through the blood inlet conduit through the wound membrane and exits the dialyzer through the blood outlet conduit. Dialysis solution flows upwardly through the wound membrane and support member over the top thereof and back down through the hollow core so as to define a generally inverted U-shape dialysis flow path.

Abstract: A support member for use in a coil dialyzer to support an elongated, tubularly-shaped, semipermeable membrane is disclosed herein. The member is embossed and has generally angularly-extending parallel ribs on both sides of the web. The ribs are arranged so that on each side there are high ribs and low ribs positioned between said high ribs. The ribs are arranged in a pattern whereby the lower ribs are at least of two different heights so that on each side of the support membrane there are ribs of at least three different heights.

Abstract: A coil dialyzer for use in an artificial kidney system which employs an elongated, open-ended tubularly-shaped, semipermeable membrane is disclosed herein. The ends of the membrane are sealed by forming a flap at each end thereof which defines a fold line extending between the longitudinal edges of the membrane. A wedge-and-groove construction is provided for grasping each folded end of the membrane so as to maintain the fold line and thereby assure the seal.

Abstract: A button-type fluid connector is disclosed herein for use in a coil dialyzer. The connector provides fluid communication between a fluid conduit and a tubularly shaped, semipermeable membrane. The connector includes a cap and an integral barrel extending from the cap. The barrel has at least one snap-lock recess in its surface and the connector is provided with a passageway which extends through the barrel and cap.

Abstract: A housing for electronic equipment includes a bottom cabinet and an upper compartment mounted thereon with the cover of the compartment including a front panel having operating buttons and/or other control features located thereon. The rear walls of the upper compartment and bottom cabinet form a common member for both sections of the apparatus. The upper compartment has a cover which includes the front panel and which cover is hinged at its upper rear corner to the upper edge of the common rear panel or closure member so as to be upwardly and rearwardly tiltable to expose the interior of the upper compartment. The common rear wall or closure member is also pivoted adjacent its bottom end on the lower cabinet so as to be rearwardly and downwardly tiltable to expose from the rear the interiors of the upper compartment and lower cabinet.

Abstract: A device for separating low density materials such as gas bubbles from a liquid is disclosed which comprises a chamber defined by an inner wall which in turn defines generally circular, transverse cross-sections about a longitudinal axis. The liquid inlet port extends through the inner wall in a position to pass liquid into the chambers circumferentially about the inner wall for swirling flow within the chamber. Accordingly, lower density components of the fluid, such as bubbles, migrate away from the inner wall toward the center of the swirling flow. An outlet port extends through the inner wall, and is spaced from the inlet port, to collect fluid which is free from the low density materials.

Abstract: There is disclosed thermoplastic silicone copolymers having polyarylcarbonate and polyarylester constituents covalently bound to a polydiorganosiloxane constituent. The copolymer is produced by reacting a dihydric phenol with a difunctional polydiorgano siloxane, an organo-diacid halide or with alkyl or aryl ester of an organo-diacid, and with phosgene or other suitable carbonate precursors. The reactions are carried out in suitable organic solvents that solubilize the reagents and the resulting copolymer, in the presence of conventional catalysts. In another embodiment a solvent system is eliminated and the condensation polymerization is carried out in a molten system.

Abstract: A reservoir for the collection, purification, and storage of blood during surgical procedures which comprises a hollow blood storage casing having a hollow, perforated member within said casing extending from end-to-end thereof. Blood defoaming means and a filter are carried by the hollow member, so that the blood defoamer and filter are noncollapsible, and extend the entire length of the chamber within the casing, with one of the ports communicating with the interior of the hollow member, so that blood passes through the perforations of the hollow member and defoamer-filter means.

Abstract: A burette chamber is provided which includes a primary and a secondary compartment, a wall member separating the primary and secondary compartments with the wall member providing an opening for communication between the primary and secondary compartments. When the burette chamber is included in an intravenous solution administration set, the set can continuously administer IV solution to a patient as well as to allow intermittent administration of medicaments with return to the continuous administration of IV solution to the patient after completion of medicament administration.

Abstract: A hydrophobic valve for use with liquids, such as liquids for intravenous administration comprising a housing provided with inlet and outlet means, both of which communicate with the housing, a resilient, inflatable boot mounted in the housing and positioned to block the flow of liquid through the outlet means when inflated and to permit the flow of liquid through the outlet means when in a deflated position, with the boot including an open portion adjacent to the inlet means which is covered by a hydrophobic filter element capable of repelling liquid but permitting the passage of gases, such as air, therethrough whereby liquid introduced to the housing through the inlet means is passed through the housing for discharge from the outlet means and any air introduced with the liquid is passed through the hydrophobic filter into the boot to stop the flow of liquid from the outlet means when the boot is inflated with the gas.

Abstract: A retractable handle assembly for an equipment housing includes a generally U-shaped handle. The side members of the handle are slidably mounted to the housing by means of guide pins which ride in elongated slots on mounting blocks attached to the housing. A communicating slot on the mounting block allows the handle when fully extended to pivot about the guide pins away from an underlying surface so as to be more easily grasped. When retracted the handle is flush with the side panels of the housing.

Abstract: A drive system for a centrifugal liquid processing apparatus or the like wherein a rotor assembly having a container for receiving a liquid to be processed by centrifugation is rotatably mounted on a rotor drive assembly, which in turn is rotatably mounted to a stationary base. Liquid communication is maintained with the container during rotation of the rotor by means of a flexible umbilical cable which extends from the container to a location external to the apparatus by way of a passageway provided in the support shaft of the rotor assembly and a guide sleeve carried on and rotatably mounted to the rotor drive assembly. The rotor assembly is rotatably driven in the same direction as the rotor drive assembly with a speed ratio of 2:1 and the guide sleeve is rotatably driven in the opposite direction with a speed equal to that of the rotor drive assembly to prevent the umbilical cable from becoming twisted during operation of the apparatus.

Abstract: A reservoir for use with blood oxygenation apparatus is described herein. A chamber separator within said reservoir defines, in the interior thereof, a primary chamber and a secondary chamber, with a flow channel, connecting the primary and secondary chambers. A plurality of intake and outlet ports communicate with the primary chamber. The reservoir may be connected to blood oxygenation apparatus via the intake and outlet ports, while the flow channel may be clamped to prevent fluid flow between the primary and the secondary chambers, when it is desired to reduce the blood volume in the reservoir.