Abstract: A novel approach to Borrelia vaccine formulation taking into account serological, genotypic and epidemiological information by which OspC proteins from different strains of B. burgdorferi are grouped together. OspC antigens are chosen in order to constitute a representative sample of such groupings, so that the resulting vaccine provides the greatest cross-protectivity with the fewest number of antigens.
Type:
Grant
Filed:
April 29, 1994
Date of Patent:
March 29, 2005
Assignee:
Baxter Vaccine AG
Inventors:
Ian Livey, Brian Crowe, Friedrich Dorner
Abstract: A novel approach to Borrelia vaccine formulation taking into account serological, genotypic and epidemiological information by which OspC proteins from different strains of B burgdorferi are grouped together. OspC antigens are chosen in order to constitute a representative sample of such groupings, so that the resulting vaccine provides the greatest cross-protectivity with the fewest number of antigens.
Type:
Grant
Filed:
June 27, 1996
Date of Patent:
November 26, 2002
Assignee:
Baxter Vaccine AG
Inventors:
Ian Livey, Brian Crowe, Friedrich Dorner
Abstract: A chimeric poxvirus is disclosed, which comprises the sequences of the vector component of a retroviral vector particle and optionally the packaging component of a defective retroviral particle. The chimeric poxvirus according to the invention particularly can be used for applications in gene therapy or tumor therapy.
Type:
Grant
Filed:
January 12, 1999
Date of Patent:
March 5, 2002
Assignee:
Baxter Vaccine AG
Inventors:
Falko-Guenter Falkner, Georg Holzer, Friedrich Dorner