Patents Assigned to Bayer AG
  • Patent number: 10152035
    Abstract: The instant disclosure provides an ability to use an array of data inputs to enter a network and thereby provide a realtime improvable database. The present invention is novel in its ability to maximize the customer's interface with a pest control system, thus allowing for maximum efficiency for current and future designs as well as a high level of compatibility with ancillary regulatory, financial and planning type functions.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: December 11, 2018
    Assignee: BAYER AG
    Inventors: Byron Reid, Volker Gutsmann, Michael Zimmermann, Chris Pienaar, Gaelle Fages, Peter Jardine
  • Patent number: 9285312
    Abstract: The invention relates to a reflection probe for measuring properties of liquid and/or solid substances, and to the use thereof.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: March 15, 2016
    Assignee: Bayer AG
    Inventors: Stephan Tosch, Reinhard Gross, Nils Weber
  • Publication number: 20150202214
    Abstract: The present invention relates to pharmaceutical compositions and combinations comprising regorafenib and acetylsalicylic acid, or a hydrate, solvate, metabolite or pharmaceutically acceptable salt thereof or a polymorph thereof for treating, preventing or managing diseases and conditions including hyperproliverative disorders such as cancer in humans and other mammals.
    Type: Application
    Filed: September 23, 2013
    Publication date: July 23, 2015
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER AG
    Inventors: Olaf Weber, Karl Ziegelbauer
  • Patent number: 8078323
    Abstract: Method for controlling the process of separating mixtures containing several substances having close boiling points and with a known concentration, in a distillation column, wherein the concentration of at least one component is measured at a midpoint of the column, and said measurement, together with other parameters, is used to control the process.
    Type: Grant
    Filed: September 6, 2002
    Date of Patent: December 13, 2011
    Assignee: Bayer AG
    Inventors: Frank Meeuwssen, Franz Ferdinand Rhiel, Torsten Hauschild, Martin Gerlach
  • Patent number: 7514565
    Abstract: The invention relates to compounds of the formule
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: April 7, 2009
    Assignee: Bayer AG
    Inventors: Jürgen Stoltefuβ, Siegfried Goldmann, Thomas Krämer, Karl-Heinz Schlemmer, Ulrich Niewöhner, Maria Niewöhner, Arnold Paeβens, Erwin Graef, Stefan Lottmann, Karl Deres, Olaf Weber, Jörn Stölting
  • Patent number: 7256158
    Abstract: The invention relates to new phenyl-substituted cyclic ketoenols of the formula (I) in which Het represents one of the groups ?wherein A, B, D, G, X, Y and Z have the meaning given in the description, several processes and intermediate products for their preparation and their use as pest control agents and herbicides.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: August 14, 2007
    Assignee: Bayer AG
    Inventors: Folker Lieb, Hermann Hagemann, Arno Widdig, Michael Ruther, Reiner Fischer, Thomas Bretschneider, Christoph Erdelen, Ulrike Wachendorff-Neumann, Peter Dahmen, Markus Dollinger, Hans Joachim Santel, Alan Graff, Norbert Mencke, Andreas Turberg
  • Publication number: 20070129355
    Abstract: The present invention relates to a pyrimidine derivative of the formula (I) and salts thereof which is useful as an active ingredient of pharmaceutical preparations. The pyrimidine derivative of the present invention has excellent CRTH2 (G-protein-coupled chemoattractant receptor, expressed on Th2 cells) antagonistic activity and can be used for the prophylaxis and treatment of diseases associated with CRTH2 activity, in particular for the treatment of allergic diseases, such as asthma, allergic rhinitis, atopic dermatitis, and allergic conjunctivitis; eosinophil-related diseases, such as Churg-Strauss syndrome and sinusitis; basophil-related diseases, such as basophilic leukemia, chronic urticaria and basophilic leukocytosis in human and other mammals; and inflammatory diseases characterized by T lymphocytes and profuse leukocyte infiltrates such as psoriasis, eczema, inflammatory bowel disease, ulcerative colitis, Crohn's disease, COPD (chronic obstructive pulmonary disorder) and arthritis.
    Type: Application
    Filed: April 14, 2004
    Publication date: June 7, 2007
    Applicants: ACTIMIS PHARMACEUTICALS, INC., BAYER AG, BAYER HEALTH CARE AG
    Inventors: Tai-wei Ly, Yuji Koriyama, Takashi Yoshino, Hiroki Sato, Kazuho Tanaka, Hiromi Sugimoto, Yoshihisa Manabe, Kevin Bacon, Klaus Urbahns, Masanori Seki, Takuya Shintani
  • Patent number: 7208175
    Abstract: Rapidly disintegrating preparations containing at least one active pharmaceutical ingredient and at least one excipient can be obtained by a simple process in which at least the predominant part of the complete composition of the ingredients for the preparation to be produced is granulated, the resulting granules and, where appropriate, the remainder of the ingredients are shaped in the presence of liquid virtually without pressure, and the resulting shaped articles are dried.
    Type: Grant
    Filed: June 19, 2003
    Date of Patent: April 24, 2007
    Assignee: Bayer Ag
    Inventors: Marco Schroeder, Klaus-Jürgen Steffens
  • Patent number: 7112660
    Abstract: The invention relates to methods for the stabilisation of cytokines and to cytokines generated by such methods. The methods of the invention involve mutating the amino acid sequence of a cytokine so as to remove solvent-exposed hydrophobic residues, and/or mutating the amino acid sequence of the cytokine so as to stabilise one or more secondary structure elements in the molecule. These steps have the effect of destabilsing intermediates that are formed during the folding process, relative to the stability of the cytokine in its naturally folded state, so increasing the yield of the cytokine as produced in vitro.
    Type: Grant
    Filed: May 23, 2000
    Date of Patent: September 26, 2006
    Assignees: European Molecular Biology Laboratory, Bayer AG
    Inventors: Helena Domingues, Hartmut Oschkinat, Luis Serrano, Joerg Peters
  • Patent number: 7091284
    Abstract: Hydrogenated copolymers of an unsaturated nitrile, butadiene and isoprene, wherein the molar ratio of butadiene to isoprene is less than 3:1, display valuable low temperature properties.
    Type: Grant
    Filed: August 21, 2001
    Date of Patent: August 15, 2006
    Assignees: Bayer AG, Bayer Inc.
    Inventors: Harald Bender, Rotraud Casper, legal representative, Hans Rafael Winkelbach, Hans Christian Strauch, Paul Nguyen, Sharon X. Guo, Janet Gamlin, Rudolf Casper, deceased
  • Patent number: 7025978
    Abstract: The present invention relates to the use of polysiloxanes containing at least one quaternary ammonium group as formulation auxiliaries in formulations of pharmaceutically and veterinary active compounds, and to compositions comprising a) pharmaceutically or veterinary active compound and b) a polysiloxane derivative containing at least one quaternary ammonium group per molecule, if appropriate, further auxiliaries and carriers.
    Type: Grant
    Filed: October 31, 2000
    Date of Patent: April 11, 2006
    Assignee: Bayer AG
    Inventors: Kirkor Sirinyan, Kerstin Heinen
  • Patent number: 7012041
    Abstract: The invention relates to novel phenylpyridazinones of the general formula (I) in which R1, R2, R3, R4, R5 and R6 are each as defined in the description, to processes for their preparation, to their use as herbicides and to novel intermediates and processes for preparing them.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: March 14, 2006
    Assignee: Bayer AG
    Inventors: Karl-Heinz Linker, Kurt Findeisen, Wilhelm Haas, Markus Dollinger, Hans-Joachim Santel
  • Patent number: 6984297
    Abstract: A method and a device are used for carrying out measurements on cells located in a liquid environment. Each cell is positioned with an underside of its membrane on a surface having a channel running through it. A negative pressure is established to aspirate the cells. Each cell is electrically scanned via at least one electrode which is spaced apart from the cell. The negative pressure is preferably established in a pulse-like manner to rupture the membrane in such a way that the cell interior enclosed by the membrane is connected to the channel.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: January 10, 2006
    Assignees: NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen, Bayer AG
    Inventors: Wilfried Nisch, Martin Stelzle, Alfred Stett, Thomas Krahn, Thomas Müller, Christoph Methfessel
  • Patent number: 6951967
    Abstract: Tertiary alcohols can be prepared by the hydration of tertiary olefins having the same number of carbon atoms on an acidic ion exchanger using special structured multi-purpose packings for heterogeneous reactive rectification. An excellent yield and purity of the alcohol and an extended service life of the catalyst are achieved.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: October 4, 2005
    Assignees: EC Erdolchemie GmbH, Bayer AG
    Inventors: Axel Gohrt, Joachim Grub, Stefan Kaminsky, Stephan Muller, Brian Schwegler
  • Patent number: 6933409
    Abstract: Noble metal/reducible metal oxide catalysts effective for the direct amination of aromatic hydrocarbons and heterocyclic analogs thereof are disclosed. In one embodiment, the cataloxidant comprises a noble metal selected from Pd, Rh, Ir and/or Ru and a reducible metal oxide. In another embodiment, the cataloxidant comprises a noble metal and a reducible oxide of a metal selected from Ni, Mn, V, Ce, Th, Pr, Te, Re, Co, Fe, Cu and/or Bi. A preferred cataloxidant comprises one or more noble metals selected from Pd, Rh, Ir and/or Ru, in combination with nickel oxide and/or manganese oxide. In preferred applications, benzene can be aminated in the presence of the cataloxidants to form aniline. A benzene conversion of at least 5% is achieved, with more than 90% selectivity for aniline. Significantly, the cataloxidant can be regenerated without a substantial loss of performance.
    Type: Grant
    Filed: May 15, 2000
    Date of Patent: August 23, 2005
    Assignees: Symyx Technologies, Inc., Bayer AG
    Inventors: Damodara M. Poojary, Ramesh Borade, Alfred Hagemeyer, Xiao Ping Zhou, Christopher E. Dube, Ulrich Notheis, Ralph Armbrust, Christian Rasp, David M. Lowe
  • Patent number: 6923715
    Abstract: A device for regulating the air volume flow for a laboratory exhaust, has a rectangular housing (6) which can be arranged on the laboratory exhaust. The device is equipped with inflow devices that can be connected to the interior of the laboratory exhaust and with outflow devices (8, 12, 13) that can be connected to an exhaust air system. The interior of housing (6) is divided by a partition (17) into two parts, namely a calming part on the exhaust side and a measurement and regulating part on the outflow side, and these two parts are connected by an air deflection area (18). A rectangular measurement orifice (20, 25) has pressure measurement devices (22, 23, 24, 28, 29) and a rectangular regulating flap (21) arranged one after the other at a distance in the direction of flow between a housing wall and the partition (17).
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: August 2, 2005
    Assignees: Waldner Laboreinrichtungen GmbH & Co. KG, Bayer AG
    Inventors: Konrad Kreuzer, Frank Barth, Horst Esch
  • Publication number: 20050164885
    Abstract: The present invention relates to new compounds of the formula (I) in which X represents halogen, Y represents halogen or alkyl and Z represents halogen or alkyl, with the proviso that always one of the radicals Y and Z represents halogen while the other represents alkyl, and Het represents one of the groups in which A, B, D and G have the meanings given in the description, to a plurality of processes for their preparation and to their use as pesticides and herbicides.
    Type: Application
    Filed: July 30, 2004
    Publication date: July 28, 2005
    Applicant: Bayer AG
    Inventors: Folker Lieb, Hermann Hagemann, Arno Widdig, Michael Ruther, Reiner Fischer, Thomas Bretschneider, Christoph Erdelen, Ulrike Wachendorff-Neumann, Peter Dahmen, Markus Dollinger, Hans-Joachim Santel, Alan Graff, Wolfram Andersch, Norbert Mencke, Andreas Turberg
  • Patent number: 6919085
    Abstract: The invention relates to a method of increasing protein expression in baculo vector virus expression systems. The invention provides a method to produce a recombinant protein in insect cell culture which comprises selecting a recombinant baculovirus expressing said protein, growing insect cells in growth medium in a culture vessel and infecting the cells with an inoculum of at least one baculovirus at a cell density of 1×105 to 5×106 cells/ml with an m.o.i of <0.01. The invention also provides a method to produce recombinant pestivirus E2 or Em9 protein or fragments thereof in insect cell culture characterized by a final concentration of the protein fragments in the growth medium at harvest of at least 100 ?g/ml. The invention also provides a method of producing recombinant FSH, ?-units and/or ?-units, and complexes and fragments thereof, at a concentration in the growth medium at harvest of at least 15 ?/ml.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: July 19, 2005
    Assignees: Stichting Instituut voor Dierhouderij en Diergezondheid, Bayer AG
    Inventors: Dietmar Kretzdorn, Dirk Franciscus Marinus van de Wiel, Abraham Johannes de Smit, Robertus Jacobus Maria Moormann, Erik Kees Hamann
  • Patent number: 6881453
    Abstract: A film which is a single polymer film and has a smaller phase difference as the wavelength becomes shorter. This film is made from an olefin-based polymer which has an alicyclic group in the side chain, such as hydrogenated polystyrene, the amount of the alicyclic group in the side chain being 60 to 90 wt % based on the whole polymer, and satisfies the following expression: R(450)/R(550)<1 wherein R(450) and R(550) are phase differences on the film plane at a wavelength of 450 nm and a wavelength of 550 nm, respectively.
    Type: Grant
    Filed: April 23, 2001
    Date of Patent: April 19, 2005
    Assignees: Teijin Limited, Bayer AG
    Inventors: Nobuaki Kido, Shunichi Matsumura, Kaoru Iwata, Takashi Kushida, Akihiko Uchiyama, Michio Yamaura, Takeshi Sasaki, Kiyonari Hashidzume
  • Patent number: 6875766
    Abstract: The invention relates to the use of riboflavin and of flavin derivatives with chitinase-inhibitory action for controlling arthropods, nematodes and chitin-containing fungi.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: April 5, 2005
    Assignee: Bayer AG
    Inventors: Andreas Turberg, Volker Gutsmann, Satosho Omura, Kazuro Shiomi