Patents Assigned to BAYER AS
  • Method for the quantification of 227AC in 223RA compositions
    Patent number: 9874550
    Abstract: A method for the quantification of 227Ac in a 223Ra composition comprising passing the composition through a first solid phase extraction column A, wherein said column comprises a thorium specific resin, passing the eluate of column A through a second solid phase extraction column B, wherein said column comprises an actinium specific resin and recovering the 227Ac absorbed onto the resin in column B and determining the amount thereof.
    Type: Grant
    Filed: August 13, 2014
    Date of Patent: January 23, 2018
    Assignee: BAYER AS
    Inventor: Gro Elisabeth Hjellum
  • Radio-pharmaceutical complexes
    Patent number: 9827336
    Abstract: A tissue-targeting complex comprising a tissue targeting moiety, an octadentate hydroxypyridinone-containing ligand comprising four HOPO moieties and the ion of an alpha-emitting thorium radionuclide, where at least one of the four HOPO moieties is substituted at the N-position with a hydroxyalkyl solubilising group.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: November 28, 2017
    Assignee: BAYER AS
    Inventors: Hanne Therese Bonge-Hansen, Olav Benjamin Ryan
  • Alpha-emitting complexes
    Patent number: 9724436
    Abstract: The present invention provides a tissue-targeting complex comprising a tissue targeting moiety, an octadentate hydroxypyridinone-containing ligand and the ion of an alpha-emitting thorium radionuclide. The invention additionally provides therapeutic methods employing such complexes, methods of their production and use, and kits and pharmaceutical compositions comprising such complexes.
    Type: Grant
    Filed: February 14, 2011
    Date of Patent: August 8, 2017
    Assignee: BAYER AS
    Inventor: Thomas Ramdahl