Abstract: This invention is directed to compounds useful as intermediates in the synthesis of lipoxin A4 analogs of the following formulas (I) and (II): wherein R1, R2, R3, R4 and R5 are described herein. These analogs are useful in treating inflammatory and autoimmune disorders in humans. These analogs are also useful in treating pulmonary or respiratory tract inflammation in humans.

Abstract: The invention relates to a continuous process for the manufacture of nitrobenzene. This process comprises the nitration of benzene with nitrating acid that contains at least 3.0 wt. % of nitric acid and at least 67.0 wt. % of sulfuric acid, in a reaction space in which the start temperature of the reaction is above 100.0° C. but below 102.0° C. In addition, this process requires that the benzene and the nitrating acid are dispersed in one another several times.

Abstract: The present invention relates to compositions for controlling plant pests containing the compound of formula (I) in a mixture with fungicidally active compounds.

Abstract: The present invention relates to a process for preparing biaryls using catalysts based on palladium compounds with phosphine ligands.

Abstract: The invention describes phenyl-substituted pyridazinones of the formula (I) as herbicides and insecticides. In this formula (I), A, B, G, X, Y and Z are radicals such as hydrogen, organic radicals such as alkyl, and other radicals such as halogen, nitro and cyano.

Abstract: The invention provides pharmacological compositions comprising PDE-5 inhibitors for the treatment of hearing impairment i.e. hearing loss and tinnitus. The invention also provides methods of screening for such PDE-5 inhibitors for use in the preparation of medicaments for the treatment of hearing impairment i.e. hearing loss and tinnitus.

Abstract: A herbicide composition for lawn characterized by containing iodosulfuron-methyl or its salt, and at least 1 kind of herbicidal compound selected from the group consisting of oxaziclomefone, fentrazamide, oxadiargyl, ethoxysulfuron, cafenstrole, indanofan, asulam, fenoxaprop, clethodim, ethofumesate, tribenuron-methyl, metsulfuron-methyl, thifensulfuron-methyl, bromoxynil, MCPA, 2,4-D, dicamba as effective components.

Abstract: The invention relates to novel heterocyclic derivatives of the general formula (I), processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction, and heart failure development.

Abstract: The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.

Abstract: The present invention relates to a catalyst for oxidation reactions which comprises at least one constituent active in the catalysis of hydrogen chloride oxidation and support therefor, characterized in that the support is based on uranium oxide. The catalyst is notable for a high stability and activity.

Abstract: A package (1) for pharmaceutical, medical or similar products, particularly pesticides or plant protection products, comprising a substantially flat element (2) for supporting indications (T) prescribed for a pharmaceutical, medical or similar product, particularly a pesticide or plant protection product, a first receptacle (3) for containing a container (4) of the product which is formed in the substantially flat element (2), and first means (5) for connecting the container (4) and the substantially flat element (2).

Abstract: Monoclonal antibody that specifically binds to alpha-amylase and is useful for detecting weather damage (i.e. pre-harvest sprouting) in cereal grain.

Abstract: This invention relates to certain biphenyl-4-yl carbonylamino acid compounds, compositions, and methods for treating or preventing obesity and related diseases.

Abstract: A functional aspartate prepared by A) reacting an aziridine with a Michael-acceptor molecule to form an aziridinyl aspartate, and B) reacting the aziridinyl aspartate with an active hydrogen containing compound to form the functional aspartate. The functional aspartate can be used in adhesive, sealant or coating compositions that also include an isocyanate functional material. The composition can be used in a method of bonding a first substrate to a second substrate that includes applying a coating of the above-identified adhesive composition to at least one surface of the first substrate or the second substrate, and contacting a surface of the first substrate with a surface of the second substrate, where at least on of the contacting surfaces has the coating applied thereto. The composition can also be used to coat substrates.

Abstract: The present invention relates to ultra-high solids content polymer polyols which have good filterability while maintaining a reasonable viscosity, and to a process for the preparation of these ultra-high solids contents polymer polyols. These polymer polyols comprise the free-radical polymerization product of (A) a base polyol, (B) a pre-formed stabilizer, (C) at least one ethylenically unsaturated monomer, (D) at least one free-radical polymerization initiator, and (E) at least one chain transfer agent. The solids contents varies from 60% to about 85% by weight.

Abstract: The present invention is directed to polyisocyanate addition compounds which i) are substantially free from isocyanate groups and are prepared from one or more a) polyisocyanate adducts and/or b) NCO prepolymers, ii) contain urethane groups, iii) contain fluorine in an amount of 0.01 to 50% by weight, and iv) contain ethylenically unsaturated groups in an amount of 2 to 40% by weight, wherein the preceding percentages are based on the solids content of the polyisocyanate addition compounds. The fluorine is incorporated by reacting an isocyanate group with a compound containing two or more carbon atoms, one or more hydroxyl groups and one or more fluorine atoms to form urethane and optionally allophanate groups. More than 50 mole % of the groups that incorporate fluorine into the addition compounds are urethane groups. The polyisocyanate addition compounds are useful in coating compositions that are curable by free radical polymerization.

Abstract: A single-sensor meter system for dispensing sensors for testing of an analyte concentration in a fluid comprises a container assembly and a single-sensor meter. The container assembly includes inner and outer cartridges. The inner cartridge includes a plurality of test sensors and a mechanical mechanism. The container assembly forms exactly one opening for dispensing the test sensors one at a time. The opening is covered by an end cap so as to assist in preventing or inhibiting moisture from entering the interior of the container assembly. The mechanical mechanism is adapted to advance the plurality of test sensors. The single-sensor meter is adapted to align with and operatively connects to the container assembly. The single-sensor meter includes a test-sensor extraction mechanism adapted to grip a test sensor and pull the test sensor through the opening to a dispensed position.