Patents Assigned to Bayer CropScience LP
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Patent number: 12527323Abstract: The present invention relates to a fusion protein having a targeting sequence, exosporium protein, or exosporium protein fragment that targets the fusion protein to the exosporium of a recombinant Bacillus cereus family member and an enzyme having serine protease activity, wherein the enzyme having serine protease activity is from Bacillus firmus or is a variant of such enzyme. The present invention also provides a recombinant Bacillus cereus family member that expresses such fusion protein and exosporium fragments derived from such recombinant Bacillus cereus family member. Methods of using such recombinant Bacillus cereus family members or exosporium fragments derived therefrom for nematode control are also provided.Type: GrantFiled: September 5, 2023Date of Patent: January 20, 2026Assignee: Bayer CropScience LPInventors: Damian Curtis, Kevin Bugg
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Patent number: 12439919Abstract: The present invention relates to active compound combinations comprising Fluopyram, at least one fungicide (B) selected from the group of inhibitors of the respiratory chain at complex I or II and at least one further fungicide (C) selected from the group of specified inhibitors of the respiratory chain at complex III, to compositions comprising such compound combination, and to the use thereof as biologically active agents, especially for control of harmful microorganisms in crop protection and in the protection of industrial materials.Type: GrantFiled: May 7, 2020Date of Patent: October 14, 2025Assignee: BAYER CROPSCIENCE LPInventors: Raymond Lello, Randy Myers, Lawrence Norton, Kelly Patzer, Jocelyn Kratchmer
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Patent number: 12408673Abstract: The present invention provides a composition comprising a biologically pure culture of a Paenibacillus sp. strain or a cell-free preparation thereof comprising a fusaricidin and a tridecaptin; wherein the fusaricidin is produced with a fusaricidin synthetase gene of fusA encoded by a DNA sequence exhibiting at least 90.5% sequence identity to SEQ ID NO: 3; and the tridecaptin is produced with a nonribosomal peptide synthetase (NRPS) gene of triE encoded by a DNA sequence exhibiting at least 90.0% sequence identity to SEQ ID NO: 7. Also provided are methods of treating an agricultural plant to control a disease and methods of increasing the vigor and/or crop yield of an agricultural plant with the disclosed compositions.Type: GrantFiled: March 5, 2020Date of Patent: September 9, 2025Assignee: Bayer CropScience LPInventors: Jeremy Beau, Andreas Goertz, Adam Newman, Patrick Schwientek, Colleen S. Taylor, Donglan Tian, Bjorn A. Traag
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Patent number: 12173278Abstract: The present invention provides a composition comprising a biologically pure culture of a Paenibacillus sp. strain comprising a mutant DegU lacking a functional receiver domain or a functional DNA binding domain and/or a mutant DegS lacking a functional single binding domain or a functional ATPase domain with decreased viscosity in a liquid culture. Also provided is a method of identifying a Paenibacillus sp. mutant derivative strain with decreased viscosity in a liquid culture compared to a Paenibacillus sp. parental strain with a visual screen for mutant isolates with a non-mucoid morphology.Type: GrantFiled: May 8, 2019Date of Patent: December 24, 2024Assignee: Bayer CropScience LPInventors: Jennifer Anne Collins, Jesus F. Sanchez, James L. Waller, Bjorn A. Traag, Sara K. Hotton, Tony J. Tegeler
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Patent number: 12016912Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.Type: GrantFiled: June 24, 2021Date of Patent: June 25, 2024Assignees: Bayer CropScience LP, Spogen Biotech Inc.Inventors: Damian Curtis, Brian Thompson
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Patent number: 12005107Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular fungicide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.Type: GrantFiled: June 24, 2021Date of Patent: June 11, 2024Assignee: Bayer CropScience LPInventors: Damian Curtis, Brian Thompson
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Patent number: 11849724Abstract: The present disclosure relates to the field of agrochemical compositions and formulations. In an aspect, the present disclosure provides for a composition in combination with a fibril or microfibril or nanofibril structuring agent. In yet another aspect, the disclosure provides for a composition comprising: (a) an agricultural bioactive material, a fungicide, insecticide, herbicide, and/or plant growth regulator; (b) a fibril or microfibril or nanofibril structuring agent; and (c) optionally, an auxiliary surface active agent. The disclosure further provides for a comprising a composition described herein mixed or combined with a liquid fertilizer.Type: GrantFiled: August 15, 2018Date of Patent: December 26, 2023Assignee: Bayer CropScience LPInventors: Milind Singh, David A. Long, Aveen Alkhatib
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Patent number: 11793196Abstract: The present invention relates to a fusion protein having a targeting sequence, exosporium protein, or exosporium protein fragment that targets the fusion protein to the exosporium of a recombinant Bacillus cereus family member and an enzyme having serine protease activity, wherein the enzyme having serine protease activity is from Bacillus firmus or is a variant of such enzyme. The present invention also provides a recombinant Bacillus cereus family member that expresses such fusion protein and exosporium fragments derived from such recombinant Bacillus cereus family member. Methods of using such recombinant Bacillus cereus family members or exosporium fragments derived therefrom for nematode control are also provided.Type: GrantFiled: March 18, 2020Date of Patent: October 24, 2023Assignee: Bayer CropScience LPInventors: Damian Curtis, Kevin Bugg
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Patent number: 11623944Abstract: The present invention relates to a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain comprising a variant fusaricidin synthetase lacking a functional adenylation domain in the third module. The present invention also provides a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain or a cell-free extract thereof comprising at least one Paeniserine and at least one Paeniprolixin. Also provided are isolated compounds and methods of treating a plant to control a plant disease with the disclosed compositions and compounds.Type: GrantFiled: October 31, 2019Date of Patent: April 11, 2023Assignee: Bayer CropScience LPInventors: Jeremy Beau, Daniel M. Joo, Patrick Schwientek, Colleen S. Taylor, Bjorn A. Traag
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Patent number: 11490624Abstract: Water-based formulations (EW) are provided containing no VOC's or alternatively are low in VOC's for wide area space spray to control mosquitoes, flies, and other public health pests. Application via ULV, these formulations have been observed to provide significantly superior control of pests when compared to competitive adulticides. The present formulations provide exceptional preservation of both droplet density in the spray cloud and droplet size as measured by volume mean diameter (VmD). The present formulations provide superior bio-efficacy as measured by both mortality and knockdown of target organisms. The present formulations provide superior biological control, droplet density, and droplet size when applied at concentrations 20-80× less than competitive formulations.Type: GrantFiled: February 18, 2020Date of Patent: November 8, 2022Assignee: BAYER CROPSCIENCE LPInventors: Robert Britt Baker, Kurt P. Vandock, Gary Gore, Byron Reid
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Patent number: 11464221Abstract: An animal trap system includes a glue board, an animal trap accelerometer sensor, and a signal unit in close proximity to and in communications with the animal trap accelerometer sensor, wherein the signal unit also contains an accelerometer sensor. The animal trap system is capable of detecting capture events, non-capture events, false positives, and/or the type of animal captured by using differential signal analysis and machine learning techniques. When an acceleration is received by the animal trap accelerometer sensor above a pre-set acceleration threshold value, it sends a capture signal to the signal unit and if the signal unit does not receive such acceleration event, the signal unit transmits a capture signal to an off-site receiver. A method of trapping one or more animals using this system is also provided.Type: GrantFiled: January 28, 2020Date of Patent: October 11, 2022Assignee: BAYER CROPSCIENCE LPInventors: Gaelle Fages, Byron Reid, Homare Teramoto, Fabien Pelissier
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Patent number: 11406107Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one further biological control agent selected from particular microorganisms disclosed herein and/or a mutant of a specific strain of a microorganism disclosed herein having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.Type: GrantFiled: July 21, 2020Date of Patent: August 9, 2022Assignees: Bayer CropScience LP, Spogen Biotech Inc.Inventors: Damian Curtis, Brian Thompson
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Patent number: 11390594Abstract: The disclosure provides for methods for preparing 2-cyanoimino-1,3-thiazolidine, which is an important building block for the preparation of crop protection active ingredients and pharmaceuticals. To this end, the disclosure provides for more efficient and improved methods of preparing 2-cyanoimino-1,3-thiazolidine.Type: GrantFiled: July 15, 2020Date of Patent: July 19, 2022Assignee: BAYER CROPSCIENCE LPInventors: Shekhar Kulkarni, Eric Rivadeneira
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Patent number: 11291154Abstract: A seed treatment apparatus provides for minimal waste of products for treating seeds, in that it is precisely controllable and automatically adjustable. A volume of seeds to be treated and a flow rate of treatment product for treating the seeds can both be sensed. At least one of the flow rate of the treatment product and the volume of seeds can automatically be adjusted if it is determined that a ratio of the flow rate of treatment product to the volume of seeds is not the same as a predetermined flow rate to volume ratio.Type: GrantFiled: November 14, 2018Date of Patent: April 5, 2022Assignee: BAYER CROPSCIENCE LPInventors: Greg A. Reineccius, Steven Schulz
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Patent number: 11186816Abstract: The disclosure is generally directed to methods for screening, identifying, and producing microorganisms capable of imparting beneficial properties to plants. In some aspects, improved plant-associated soil microorganisms are generated by experimental evolution using a plant root exudate or root exudate compound.Type: GrantFiled: January 10, 2019Date of Patent: November 30, 2021Assignee: Bayer CropScience LPInventors: Varghese P. Thomas, Benjamin L. Golomb, Damian Curtis
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Patent number: 11166463Abstract: Methods and compositions for controlling undesired vegetation in animal grazelands.Type: GrantFiled: December 11, 2019Date of Patent: November 9, 2021Assignee: Bayer CropScience LPInventors: Harold Quicke, David R. Spak, Derek J. Sebastian, Roland Maynard
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Patent number: 11154064Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one further biological control agent selected from particular microorganisms disclosed herein and/or a mutant of a specific strain of a microorganism disclosed herein having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.Type: GrantFiled: September 17, 2015Date of Patent: October 26, 2021Assignees: Bayer CropScience LP, Spogen Biotech Inc.Inventors: Damian Curtis, Brian Thompson
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Patent number: 11140903Abstract: Provided are methods for reducing the occurrence of sudden death syndrome in plants, such as soybeans, using compounds of the general formula (I).Type: GrantFiled: May 7, 2018Date of Patent: October 12, 2021Assignee: Bayer CropScience LPInventors: Jennifer Riggs, David Doran
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Patent number: 11044916Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular insecticide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.Type: GrantFiled: September 17, 2015Date of Patent: June 29, 2021Assignees: Bayer CropScience LP, Spogen Biotech Inc.Inventors: Damian Curtis, Brian Thompson
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Patent number: 11044915Abstract: The present invention relates to a composition comprising a) recombinant exosporium-producing Bacillus cells that express a fusion protein comprising: (i) at least one plant growth stimulating protein or peptide and (ii) a targeting sequence that localizes the fusion protein to the exosporium of the Bacillus cells; and b) at least one particular fungicide disclosed herein in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for enhancing plant growth, promoting plant health, and/or reducing overall damage of plants and plant parts.Type: GrantFiled: September 17, 2015Date of Patent: June 29, 2021Assignees: Bayer CropScience LP, Spogen Biotech Inc.Inventors: Damian Curtis, Brian Thompson