Patents Assigned to BAYER HEALTHCARE LLC - DIABETES CARE
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Publication number: 20130240377Abstract: The present invention relates to systems, methods, and devices for determining the concentration of an analyte in a sample. The use of linear, cyclic, or acyclic voltammetric scans and/or semi-integral, derivative, or semi-derivative data treatment may provide for increased accuracy when determining the concentration of an analyte in a sample. Hematocrit compensation in combination with the data treatments may reduce the hematocrit effect with regard to a glucose analysis in whole blood. In another aspect, fast scan rates may reduce the hematocrit effect.Type: ApplicationFiled: September 12, 2012Publication date: September 19, 2013Applicant: BAYER HEALTHCARE LLC - DIABETES CAREInventor: Huan-Ping Wu
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Publication number: 20130186755Abstract: A biosensor system for determining the concentration of an analyte in a sample includes a plurality of test sensors, and includes a container including a desiccant and the plurality of test sensors, sealed in the container. When the container is stored for two weeks at a temperature of 50° C., and each test sensor is subsequently removed from the container, connected through the at least two conductors to a measurement device and then contacted with one of a plurality of samples including an analyte, where the plurality of samples has analyte concentrations that span the range of 50 mg/dL-600 mg/dL, and the analyte concentration in each sample is determined by the test sensor and the measuring device, the bias of each determined analyte concentration may be within ±10 mg/dL or ±10%, and the coefficient of variation of the determined analyte concentrations may be at most 2.5%.Type: ApplicationFiled: July 19, 2012Publication date: July 25, 2013Applicant: BAYER HEALTHCARE LLC - DIABETES CAREInventors: Amy H. Chu, Mary Ellen Warchal-Windham
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Publication number: 20120305410Abstract: A reagent composition for a biosensor sensor strip is disclosed that provides for rapid rehydration after drying. The composition includes porous particles and is preferably formed as a colloidal suspension. The dried reagent composition including porous particles may provide analytically useful output from the sensor strip in a shorter time period than observed from dried reagent compositions using solid particles. The output signal from the porous particle compositions may be correlated to the analyte concentration of a sample within about two seconds. In this manner, an accurate concentration determination of an analyte concentration in a sample may be obtained in less time than from sensor strips including conventional compositions. The reagent composition including the porous particles also may allow for the redox reaction between the reagents and the analyte to reach a maximum kinetic performance in a shorter time period than observed from conventional sensor strips.Type: ApplicationFiled: July 23, 2012Publication date: December 6, 2012Applicant: BAYER HEALTHCARE LLC - DIABETES CAREInventor: Boru Zhu
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Publication number: 20120298507Abstract: A sensor system including devices and methods for determining the concentration of an analyte in a sample is described. Input signals including amperometric and voltammetric duty cycles of excitations and relaxations may provide a shorter analysis time and/or improve the accuracy and/or precision of the analysis. The disclosed system may reduce analysis errors, thus improving measurement performance, by adjusting the potential and/or scan rate in response to output currents obtained from voltammetric scans. The disclosed system also may determine the concentration of more than one ionizable species in the sample by adjusting the potential and/or scan rate in response to output currents obtained from voltammetric scans. The multiple, determined concentrations may be used to determine the concentration of multiple analytes or to correct the concentration determined for an analyte, thus improving the measurement performance of the system.Type: ApplicationFiled: July 19, 2012Publication date: November 29, 2012Applicant: BAYER HEALTHCARE LLC - DIABETES CAREInventor: Huan-Ping Wu
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Publication number: 20120271559Abstract: A biosensor has an abnormal output detection system that determines whether an output signal from the redox reaction of an analyte has a normal or abnormal shape or configuration. The abnormal output detection system improves the accuracy and precision of the biosensor in determining whether an output signal has a shape or configuration that may not provide an accurate and/or precise analysis of a biological fluid. The biosensor generates an output signal in response to the redox reaction of the analyte. The biosensor normalizes the output signal and compares the normalized output signal with one or more control limits. The biosensor may generate an error signal when the normalized output signal is not within the control limits.Type: ApplicationFiled: June 28, 2012Publication date: October 25, 2012Applicant: BAYER HEALTHCARE LLC - DIABETES CAREInventors: Scott Carpenter, Christine D. Nelson, Huan-Ping Wu
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Publication number: 20080179197Abstract: A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Gated voltammetric pulse sequences including multiple duty cycles of sequential excitations and relaxations may provide a shorter analysis time and/or improve the accuracy and/or precision of the analysis. The disclosed pulse sequences may reduce analysis errors arising from the hematocrit effect, variance in cap-gap volumes, non-steady-state conditions, mediator background, a single set of calibration constants, under-fill, and changes in the active ionizing agent content of the sensor strip.Type: ApplicationFiled: February 26, 2008Publication date: July 31, 2008Applicant: BAYER HEALTHCARE LLC, DIABETES CARE DIVISIONInventor: Huan-Ping WU
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Publication number: 20080173552Abstract: A sensor system, device, and methods for determining the concentration of an analyte in a sample is described. Gated amperometric pulse sequences including multiple duty cycles of sequential excitations and relaxations may provide a shorter analysis time and/or improve the accuracy and/or precision of the analysis. The disclosed gated amperometric pulse sequences may reduce analysis errors arising from the hematocrit effect, variance in cap-gap volumes, non-steady-state conditions, mediator background, under-fill, temperature changes in the sample, and a single set of calibration constants.Type: ApplicationFiled: December 19, 2007Publication date: July 24, 2008Applicant: BAYER HEALTHCARE LLC, DIABETES CARE DIVISIONInventors: Huan-Ping Wu, Christine D. Nelson, Greg P. Beer
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Publication number: 20080105568Abstract: The present invention relates to systems, methods, and devices for determining the concentration of an analyte in a sample. The use of linear, cyclic, or acyclic voltammetric scans and/or semi-integral, derivative, or semi-derivative data treatment may provide for increased accuracy when determining the concentration of an analyte in a sample. Hematocrit compensation in combination with the data treatments may reduce the hematocrit effect with regard to a glucose analysis in whole blood. In another aspect, fast scan rates may reduce the hematocrit effect.Type: ApplicationFiled: May 16, 2005Publication date: May 8, 2008Applicant: Bayer Healthcare LLC, Diabetes Cares DivisionInventor: Huan-Ping Wu