Abstract: The invention relates to a composition comprising at least one aminobenzamide compound or a salt thereof for controlling animal parasites, veterinary pharmaceutical compositions comprising at least one aminobenzamide of formula (I) for preventing infection with diseases transmitted through parasites, its use for the preparation of a veterinary pharmaceutical for controlling animal parasites, and a method for preventing infection with diseases transmitted through parasites.
Abstract: The present invention relates to the use of cathepsin K and/or cathepsin S inhibitors in a method for the treatment and/or prophylaxis of pulmonary hypertension and/or heart failure.
Type:
Grant
Filed:
May 11, 2012
Date of Patent:
April 17, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Stefan Golz, Martina Delbeck, Heinrich Meier, Andreas Geerts, Thomas Mondritzki, Hubert Trübel
Abstract: Heteroarylpiperidine and -piperazine derivatives of the formula (I) in which the symbols A, X, Y, L1, L2, G, Q, p, R1, R2 and R10 are each as defined in the description, and salts, metal complexes and N-oxides of the compounds of the formula (I), and the use thereof for controlling phytopathogenic harmful fungi and processes for preparing compounds of the formula (I).
Type:
Grant
Filed:
July 5, 2016
Date of Patent:
April 3, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Tomoki Tsuchiya, Pierre Wasnaire, Sebastian Hoffmann, Pierre Cristau, Thomas Seitz, Joachim Kluth, Stefan Hillebrand, Juergen Benting, Daniela Portz, Ulrike Wachendorff-Neumann
Abstract: The invention relates to novel heteroaryl carboxamides, a process for their preparation, and pharmaceutical compositions containing them. These materials are useful for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.
Type:
Grant
Filed:
August 24, 2015
Date of Patent:
March 27, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Martin Hendrix, Frank-Gerhard Böβ, Christina Erb, Joachim Krüger, Christoph Methfessel, Rudy Schreiber, Welf-Burkhard Wiese, Joachim Luithle
Abstract: The invention relates to a method of finding compounds which increase the tolerance of plants to abiotic stress factors acting on this plant, such as, for example, temperature (such as chill, frost or heat), water (such as dryness, drought or anoxia), or the chemical load (such as lack of or excess of mineral salts, heavy metals, gaseous noxious substances) by increasing the expression of plant-endogenous proteins, and to the use of these compounds for increasing the tolerance in plants to abiotic stress factors.
Type:
Grant
Filed:
August 6, 2014
Date of Patent:
March 20, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Arno Schulz, Klaus Bartsch, Hansjörg Krähmer, Martin Hills, Erwin Hacker, Chris Rosinger
Abstract: The present invention relates to compositions for controlling plant pests, which contain the compound of the formula (I) in a mixture with fungicidally active compounds, except for cyclopropylcarboxamide derivatives and azolylmethylcycloalkanes.
Type:
Grant
Filed:
October 19, 2016
Date of Patent:
March 20, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Christoph Erdelen, Wolfram Andersch, Klaus Stenzel, Astrid Mauler-Machnik, Wolfgang Krämer
Abstract: The present invention relates to alternan-carboxylic acid esters, to processes for the preparation of alternan-carboxylic acid esters, and to compositions comprising alternan-carboxylic acid esters and to the use of alternan-carboxylic acid esters. The invention relates to alternan-carboxylic acid esters which are emulsifiers.
Abstract: Heteroarylpiperidine and -piperazine derivatives of the formula (I) in which the symbols A, X, Y, L1, L2, G, Q, p, R1, R2 and R10 are each as defined in the description, and salts, metal complexes and N-oxides of the compounds of the formula (I), and the use thereof for controlling phytopathogenic harmful fungi and processes for preparing compounds of the formula (I).
Type:
Grant
Filed:
October 31, 2016
Date of Patent:
March 13, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Stefan Hillebrand, Pierre Cristau, Sebastian Hoffmann, Joachim Kluth, Pierre Wasnaire, Tomoki Tsuchiya, Juergen Benting, Ulrike Wachendorff-Neumann, Thomas Seitz
Abstract: The invention relates to novel amides of acetic and propionic acids, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning ability and memory.
Type:
Grant
Filed:
August 5, 2016
Date of Patent:
March 13, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Joachim Luithle, Frank-Gerhard BÖβ, Christina Erb, Katrin Schnizler, Timo Flessner, Marja van Kampen, Christoph Methfessel
Abstract: The invention relates to pharmaceutical compositions for emergency contraception, to the use of levonorgestrel in combination with COX inhibitors for the preparation of pharmaceutical compositions for the stated purpose, and to a method for preparing these pharmaceutical compositions.
Type:
Grant
Filed:
December 12, 2014
Date of Patent:
March 6, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY, GmbH
Inventors:
Bernhard Lindenthal, Rolf Schürmann, Sascha General
Abstract: This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.
Type:
Grant
Filed:
November 25, 2014
Date of Patent:
February 27, 2018
Assignee:
Bayer Intellectual Property GmbH
Inventors:
William Scott, Ningshu Liu, Manfred Möwes, Andrea Hägebarth, Ursula Mönning, Ulf Bömer
Abstract: An aqueous or powder composition includes anti-gram-negative antibiotic or salt thereof being present at an amount ranging from about 100 mg/ml to about 200 mg/ml. Another aqueous or powder composition includes anti-gram-positive antibiotic or salt thereof being present at a concentration ranging from about 0.6 to about 0.9 of the water solubility limit, at 25° C. and 1.0 atmosphere, of the anti-gram-positive antibiotic or salt thereof. Other embodiments include unit doses, kits, and methods.
Abstract: The invention relates to the use of succinate dehydrogenase inhibitors, especially of fluopyram, for controlling Sclerotinia ssp., to a method for treating plants or plant parts for controlling Sclerotinia ssp. and to a method for treating seed for controlling Sclerotinia ssp. in the seed and in the plants which grow from the seed, by treating the seed with a succinate dehydrogenase inhibitor.
Type:
Grant
Filed:
December 22, 2015
Date of Patent:
January 30, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Ingo Wetcholowsky, Heiko Rieck, Gilbert Labourdette, Jose Augusto Geraldes
Abstract: The present invention relates to novel active ingredient combinations which consist of fluopyram and other known active ingredients and are very well suited for the control of animal pests, such as insects and/or unwanted acarids and/or nematodes, in foliar and soil application and/or in the treatment of seeds, and are also suitable for increasing yields.
Type:
Grant
Filed:
November 30, 2011
Date of Patent:
January 23, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Heike Hungenberg, Heiko Rieck, Robert Masters
Abstract: The invention relates to N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improvement in cognition, concentration power, learning power and/or memory.
Type:
Grant
Filed:
November 25, 2015
Date of Patent:
January 16, 2018
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Timo Fleβner, Frank-Gerhard Böβ, Frank-Thorsten Hafner, Joachim Luithle, Christoph Methfessel, Leila Telan
Abstract: The invention concerns a novel silica sol material and its use for producing bioabsorbable and biodegradable silica gel materials having improved properties. The materials such as for example fibers, fibrous nonwoven webs, powders, monoliths and/or coatings are used, for example, in medical technology and/or human medicine, in particular for wound treatment.
Abstract: A composition comprising a compound of formula (I): in which R1, R2, R3, R4, R5, R6, A, Q and n can have the definitions stated in the description, and at least one biological control agent selected from bacteria, fungi or yeasts, protozoas, viruses, entomopathogenic nematodes, and botanical extracts, or products produced by microorganisms including proteins or secondary metabolites, and optionally an inoculant, for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, nematodes and phytopathogens.
Abstract: The present invention relates to a novel process for preparing cis-alkoxy-substituted spirocyclic phenylacetylamino acid esters and cis-alkoxy-substituted spirocyclic 1H-pyrrolidine-2,4-dione derivatives, and also to novel intermediates and starting materials which are produced and/or used in the process according to the invention.
Type:
Grant
Filed:
May 23, 2016
Date of Patent:
December 12, 2017
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Taraneh Farida, Berndt Maiwald, Martin Littmann, Winfried Etzel, Rafael Warsitz, Nicolas Henck, Michael Esser
Abstract: The present invention provides immunoconjugates composed of antibodies, e.g., monoclonal antibodies, or antibody fragments that bind to mesothelin, that are conjugated to cytotoxic agents, e.g., maytansine, or derivatives thereof, and/or co-administered or formulated with one or more additional anti-cancer agents. The immunoconjugates of the invention can be used in the methods of the invention to treat and/or diagnose and/or monitor cancers, solid tumors, recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for the membrane-anchored, 40 kDa mesothelin polypeptide, which which is overexpressed in several tumors, such as pancreatic and ovarian tumors, mesothelioma and lung cancer cells.
Type:
Application
Filed:
July 21, 2017
Publication date:
November 16, 2017
Applicant:
Bayer Intellectual Property GmbH
Inventors:
Antje KAHNERT, Kerstin UNTERSCHEMMANN, Iring HEISLER, Charlotte KOPITZ, Joachim SCHUMACHER
Abstract: The invention relates to novel compounds of the formula (I) in which W, X, Y, Z, A and G have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides and/or fungicides. Moreover, the invention relates to selectively herbicidal compositions comprising, firstly, the spiroheterocyclically substituted tetramic acid derivatives and, secondly, a crop plant compatibility-improving compound. The present invention furthermore relates to the boosting of the action of crop protection compositions comprising in particular spiroheterocyclically substituted tetramic acid derivatives through the addition of ammonium or phosphonium salts and optionally penetrants, to the corresponding compositions, to processes for their preparation and to their use in crop protection as insecticides and/or acaricides and/or fungicides and/or for preventing unwanted vegetation.
Type:
Grant
Filed:
February 10, 2011
Date of Patent:
November 7, 2017
Assignee:
BAYER INTELLECTUAL PROPERTY GMBH
Inventors:
Reiner Fischer, Arnd Voerste, Isolde Häuser-Hahn, Stefan Lehr, Elmar Gatzweiler, Ulrich Görgens, Ines Heinemann