Patents Assigned to Bayer Oy
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Patent number: 11911312Abstract: The invention relates to an inserter for an intrauterine system, including a handle (3) having a longitudinal opening (8) at its first end, the opening (8) having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end (8a) and a second end (8b), a moveable slider (5) arranged in the longitudinal opening (8) and having a first end (5a) and a second end (5b), a plunger (2) attached to the handle (3), an insertion tube (6) arranged around the plunger (2) having a first end and a second end, with its second end attached to the slider (5). The inserter further includes a lock that reversibly locks the intrauterine system in relation to the plunger (2) via a removal string of the intrauterine system, the lock being controllable by the slider (5) and/or the insertion tube (6).Type: GrantFiled: May 12, 2022Date of Patent: February 27, 2024Assignee: Bayer OyInventors: Ilkka Jutila, Heikki Lyytikäinen, Ulla Calvo Alonso, Taina Tjäder, Marjo Ali-Äijälä
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Patent number: 11872155Abstract: The present invention relates to an inserter for an intrauterine system comprising a handle (3), and an insertion tube (6) having a first end and a second end, and being arranged in connection with the handle. The inserter is characterized in that the first end of the insertion tube (6) comprises at least one frame slot for receiving a frame of the intrauterine system. The invention also relates to a kit comprising an inserter according to the present invention and an intrauterine system, wherein the intrauterine system (1) comprises a therapeutic component (1b) and a continuous, closed frame (1a), the therapeutic component (1b) being connected to the frame (1a) at least one point, and therapeutic component (1b) of the intrauterine system (1) is at least mainly arranged inside the first end of the insertion tube (6) and the frame (1a) of the intrauterine system (1) is at least mainly arranged outside the first end of the insertion tube (6).Type: GrantFiled: February 17, 2020Date of Patent: January 16, 2024Assignee: Bayer OyInventors: Heikki Lyytikäinen, Ilkka Jutila, Ulla Calvo Alonso, Harri Jukarainen, Taina Träder, Andrew MacLeod, Michael Noble, David Whitaker
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Patent number: 11850182Abstract: The invention relates to an inserter for an intrauterine system, including a handle (3) having a longitudinal opening (8) at its first end, the opening (8) having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end (8a) and a second end (8b), a moveable slider (5) arranged in the longitudinal opening (8) and having a first end (5a) and a second end (5b), a plunger (2) attached to the handle (3), an insertion tube (6) arranged around the plunger (2) having a first end and a second end, with its second end attached to the slider (5). The inserter further includes a lock that reversibly locks locking the intrauterine system in relation to the plunger (2) via a removal string of the intrauterine system, the lock being controllable by the slider (5) and/or the insertion tube (6).Type: GrantFiled: May 12, 2022Date of Patent: December 26, 2023Assignee: Bayer OyInventors: Ilkka Jutila, Heikki Lyytikäinen, Ulla Calvo Alonso, Taina Tjäder, Marjo Ali-Äijälä
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Patent number: 11666552Abstract: The present invention relates to a method for modifying release of a therapeutically active agent from an elastomeric matrix, comprising providing a core comprising an elastomeric matrix and a therapeutically active agent; dipping the core to a coating solution of an elastomer, wherein the elastomer comprises 20-35 wt-% of a filler, calculated from the total amount of filler and elastomer; curing the dipped core to provide a coated core. In this method the dipping is provided as a continuous process by pulling the core through the coating solution, using a pulling speed suitable for providing a coating thickness of ?-IOO the filler is selected from silica, titanium dioxide, barium sulphate, carbon and mixtures thereof; the elastomer comprised in the core and the elastomer comprised in the coating solution are independently selected from poly(dimethyl) siloxanes, polyethylene vinyl acetates (EVAs), polyurethanes (PUs), polyhydroxyethyl methacrylates (PHEMAs) and polymethyl methacrylates (PMMAs).Type: GrantFiled: September 19, 2018Date of Patent: June 6, 2023Assignee: Bayer OYInventors: Manja Ahola, Risto Hakala, Piia Hara, Antti Keinänen, Henriikka Korolainen, Jyrki Pihlaja
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Patent number: 11628088Abstract: The present invention relates to ultrasonically detectable intrauterine systems and to a method for enhancing ultrasound detection of these systems. An intrauterine system having an inert metal coating on at least part of the body of the intrauterine system or at least one inert metal clip, pin, ring or sleeve fixedly positioned on the body of the intrauterine system is described.Type: GrantFiled: December 12, 2014Date of Patent: April 18, 2023Assignee: Bayer OYInventors: Taina Tjäder, Sara Heinonen
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Publication number: 20230039977Abstract: Disclosed is an inserter (1100, 1300, 1400, 1500) for an intrauterine system (1102, 1336, 1402, 1502), comprising a handle body (1104, 1306, 1416, 1504), a measurement tube (1110, 1328, 1406, 1510), a plunger (1132, 1202, 1362, 1450, 1532), a flange (1122, 1404, 1522), a finger holder (1124, 1314, 1446, 1524), and a means (1126, 1526) for reversibly locking removal thread (1128, 1358, 1414) of the intrauterine system. A proximal end (1106, 1440, 1506) of the measurement tube is movably attached to a distal end (1108, 1330, 1454, 1508) of the handle body, and the measurement tube is arranged to remain outside a cervix channel during insertion. The plunger is movably arranged inside the handle body and the measurement tube. The present disclosure also provides a kit comprising the inserter and the intrauterine system.Type: ApplicationFiled: January 20, 2021Publication date: February 9, 2023Applicant: Bayer OyInventors: Taina TJÄDER, Mikael STOLT, Heikki SALO, Mira KAUTTO, Marina ALLEN, Kimmo LAAKSONEN, Jari RISKI, Petri PERÄLÄ
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Publication number: 20230042677Abstract: Disclosed is an intrauterine system (100, 300, 400, 500, 600) comprising a frame (102, 302, 402, 502, 602), a removal thread (218, 326, 436, 626) and at least one pharmaceutically active agent. The frame has a first end (104, 304, 404, 504, 604), a second end (106, 306, 406, 506, 606) and a length L. The first end of the frame comprises a first locking part (108, 308, 408, 508, 608) and the second end of the frame comprises a second locking part (110, 310, 410, 510, 610), the first locking part and the second locking part being arranged to form a lock (202, 312, 432). The removal thread is attached to the first end of the frame. The removal thread is configured to guide the first locking part to the second locking part. Further, disclosed is a kit comprising the aforementioned intrauterine system and an inserter.Type: ApplicationFiled: January 20, 2021Publication date: February 9, 2023Applicant: Bayer OyInventors: Mikael STOLT, Taina TJÄDER, Christine TALLING, Risto HAKALA, Heikki SALO, Mira KAUTTO, Marina ALLEN, Jari RISKI, Petri PERÄLÄ
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Patent number: 11432958Abstract: The present invention relates to an inserter for an intrauterine system, comprising a handle (3) having a longitudinal opening (8) at its first end, said opening (8) having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end (8a) and a second end (8b), a movable slider (5) arranged in said longitudinal opening (8) and having a first end (5a) and a second end (5b), a plunger (2) attached to the handle (3) and having a longitudinal axis, and an insertion tube (6) having a first end, a second end and a longitudinal axis essentially parallel to the longitudinal axis of the plunger (2), the insertion tube (6) being, along said longitudinal axis, movably arranged around the plunger (2).Type: GrantFiled: March 9, 2020Date of Patent: September 6, 2022Assignee: Bayer OyInventors: Heikki Lyytikäinen, Ilkka Jutila, Ulla Calvo Alonso, Harri Jukarainen, Taina Tjäder, Andrew Macleod, Michael Noble, David Whitaker
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Publication number: 20220273487Abstract: The invention relates to an inserter for an intrauterine system, comprising a handle (3) having a longitudinal opening (8) at its first end, said opening (8) having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end (8a) and a second end (8b), a moveable slider (5) arranged in said longitudinal opening (8) and having a first end (5a) and a second end (5b), a plunger (2) attached to the handle (3), an insertion tube (6) arranged around the plunder (2) having a first end and a second end, with its second end attached to the slider (5), wherein the inserter further comprises locking means for reversibly locking the intrauterine system in relation to the plunder (2) via a removal string of the intrauterine system, said locking means being controllable by the slider (5) and/or the insertion tube (6).Type: ApplicationFiled: May 12, 2022Publication date: September 1, 2022Applicant: Bayer OyInventors: Ilkka Jutila, Heikki Lyytikäinen, Ulla Calvo Alonso, Taina Tjäder, Marjo Ali-Äijälä
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Publication number: 20220265466Abstract: The invention relates to an inserter for an intrauterine system, comprising a handle (3) having a longitudinal opening (8) at its first end, said opening (8) having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end (8a) and a second end (8b), a moveable slider (5) arranged in said longitudinal opening (8) and having a first end (5a) and a second end (5b), a plunger (2) attached to the handle (3), an insertion tube (6) arranged around the plunder (2) having a first end and a second end, with its second end attached to the slider (5), wherein the inserter further comprises locking means for reversibly locking the intrauterine system in relation to the plunder (2) via a removal string of the intrauterine system, said locking means being controllable by the slider (5) and/or the insertion tube (6).Type: ApplicationFiled: May 12, 2022Publication date: August 25, 2022Applicant: Bayer OyInventors: Ilkka Jutila, Heikki Lyytikäinen, Ulla Calvo Alonso, Taina Tjäder, Marjo Ali-Äijälä
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Publication number: 20220265465Abstract: The invention relates to an inserter for an intrauterine system, comprising a handle (3) having a longitudinal opening (8) at its first end, said opening (8) having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end (8a) and a second end (8b), a moveable slider (5) arranged in said longitudinal opening (8) and having a first end (5a) and a second end (5b), a plunger (2) attached to the handle (3), an insertion tube (6) arranged around the plunder (2) having a first end and a second end, with its second end attached to the slider (5), wherein the inserter further comprises locking means for reversibly locking the intrauterine system in relation to the plunder (2) via a removal string of the intrauterine system, said locking means being controllable by the slider (5) and/or the insertion tube (6).Type: ApplicationFiled: May 12, 2022Publication date: August 25, 2022Applicant: Bayer OyInventors: Ilkka Jutila, Heikki Lyytikäinen, Ulla Calvo Alonso, Taina Tjäder, Marjo Ali-Äijälä
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Publication number: 20210307957Abstract: The invention relates to an inserter for an intrauterine system, comprising a handle (3) having a longitudinal opening (8) at its first end, said opening (8) having a longitudinal axis parallel to the longitudinal axis of the inserter, a first end (8a) and a second end (8b), a moveable slider (5) arranged in said longitudinal opening (8) and having a first end (5a) and a second end (5b), a plunger (2) attached to the handle (3), an insertion tube (6) arranged around the plunder (2) having a first end and a second end, with its second end attached to the slider (5), wherein the inserter further comprises locking means for reversibly locking the intrauterine system in relation to the plunder (2) via a removal string of the intrauterine system, said locking means being controllable by the slider (5) and/or the insertion tube (6).Type: ApplicationFiled: April 23, 2021Publication date: October 7, 2021Applicant: Bayer OyInventors: Ilkka Jutila, Heikki Lyytikäinen, Ulla Calvo Alonso, Taina Tjäder, Marjo Ali-Äijälä
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Patent number: 11135085Abstract: Disclosed are an inserter and an inserter kit for an intrauterine system. The inserter comprises an insertion tube having a first end and an opposite second end, wherein the first end is operable to removably receive the intrauterine system and a handle having a first end portion and an opposite second end portion, the first end portion of the handle is coupled to the second end of the insertion tube. The handle comprises a handling mechanism for controlling movement of the insertion tube with respect to the intrauterine system. The inserter also comprises an indicating mechanism operatively arranged in connection with the insertion tube and the handle, the indicating mechanism is communicably coupled to the handling mechanism and is operable to provide indicative signals corresponding to operational stages of the inserter. The indicative signals comprise at least one light signal and the indicating mechanism comprises a power source.Type: GrantFiled: October 10, 2017Date of Patent: October 5, 2021Assignee: BAYER OYInventors: Joonas Mikkonen, Tero Jalkanen, Mikko Virtanen, Taina Tjäder, Karym El Sayed
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Publication number: 20210298942Abstract: An inserter for an intrauterine system can include a handle having an opening, a slider arranged in the opening, a plunger attached to the handle, an insertion tube attached to the slider and arranged around the plunger, and a lock adapted to reversibly lock at least one removal string of the intrauterine system. The lock can include a main part comprising an opening, the main part being rotatably mounted on a shaft or axle, an extension of the main part, and a counterpart. The at least one removal string passes through the opening of the main part and is immobilized between the main part and the counterpart when the lock is in a locking position. The slider is configured to press against the extension of the main part and turn the main part around the shaft or axle to release the at least one removal string as the slider is moved backwards.Type: ApplicationFiled: April 23, 2021Publication date: September 30, 2021Applicant: Bayer OyInventors: Ilkka Jutila, Heikki Lyytikäinen, Ulla Calvo Alonso, Taina Tjäder, Marjo Ali-Äijälä
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Patent number: 11096888Abstract: The invention relates to a method for altering the release characteristics of a long acting drug delivery device containing at least two drugs in different segments, wherein the segments are arranged to a specific sequence. The invention furthermore relates to a drug delivery device with reduced initial burst containing two different drugs in different segments. The invention further relates to a delivery device manufactured according to the a.m. method and its use in contraception and gynecological therapies.Type: GrantFiled: May 9, 2016Date of Patent: August 24, 2021Assignee: Bayer OYInventors: Savante Holmberg, Christine Talling
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Patent number: D942247Type: GrantFiled: July 23, 2020Date of Patent: February 1, 2022Assignee: Bayer OyInventors: Kimmo Laaksonen, Jari Riski, Taina Tjader
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Patent number: D942248Type: GrantFiled: July 23, 2020Date of Patent: February 1, 2022Assignee: Bayer OyInventors: Kimmo Laaksonen, Jari Riski, Taina Tjader
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Patent number: D942249Type: GrantFiled: July 23, 2020Date of Patent: February 1, 2022Assignee: Bayer OyInventors: Kimmo Laaksonen, Jari Riski, Taina Tjader
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Patent number: D942250Type: GrantFiled: July 23, 2020Date of Patent: February 1, 2022Assignee: Bayer OyInventors: Kimmo Laaksonen, Jari Riski, Taina Tjader
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Patent number: D942251Type: GrantFiled: July 23, 2020Date of Patent: February 1, 2022Assignee: Bayer OyInventors: Kimmo Laaksonen, Jari Riski, Taina Tjader