Abstract: The invention relates to a method for preparing 2,5-dimethylphenylacetic acid by converting p-xylene with chloroacetyl chloride into 2-chloro-1-(2,5-dimethylphenyl)ethanone, which is reacted with the compound of the formula (II) to give the compound of the formula (III), which is then rearranged to give a mixture of the compounds (IV) and (V), which is then hydrolyzed to 2,5-dimethylphenylacetic acid.

Abstract: The invention relates to insecticidal mixtures containing, as active substances, at least two compounds from the series of the chloronicotinyl insecticides, and to the use of these mixtures for promoting plant growth.

Abstract: The present invention relates to novel morpholine-bridged indazole derivatives having the formula which stimulate soluble guanylate cyclase, to a process for the preparation thereof, and to pharmaceutical compositions containing them. These compounds are useful for the treatment of disorders of the central nervous system.

Abstract: A process for the preparation of high purity bisphenol A is disclosed. The multi-step process entails a process whereby bisphenol A of a purity of preferably at least 99.8% can be obtained.

Abstract: The present invention relates to antibodies, and antigen-binding antibody fragments, directed against an RG1 polypeptide. The invention further relates to methods for utilizing the antibodies, and antibody fragments, for diagnostic and therapeutic applications.

Abstract: An animal ear tag includes a tag body and a locking insert, wherein once the locking insert is placed within the boss of a receptacle of the body of the ear tag, the insert is not easily dislodged therefrom. In addition, the present invention relates to an animal ear tag and locking insert wherein the locking insert prevents separation of the locking components of the animal ear tag once the ear tag is installed on an animal, thereby inhibiting loss of the ear tag.

Abstract: The present invention relates to the use of a compound for plant growth regulation, preferably by application of the compound to plants, to the seeds from which they grow or to the locus in which they grow, in an effective plant growth regulating, preferably non-phytotoxic amount, which compound is an indolinone derivative of formula (I) or an agriculturally acceptable salt thereof: wherein: X is NNHR2, NNHC(?S)NH—(C1-C6)alkyl or a formula (A): in which the point of attachment is the carbon atom marked 2, and a method for treatment of plants with such compounds in order to induce growth regulating responses.

Abstract: The present invention relates to novel phenyl-substituted 4-ketolactams and -lactones of the formula (I) in which A, B, Q, G, W, X, Y, Z and R3 are as defined above, to processes and intermediates for their preparation and to their use as pesticides, microbicides and herbicides.

Abstract: This invention relates to solutions of polyurethaneureas in ?-butyrolactone or mixtures of ?-butyrolactone with toxicologically acceptable organic solvents. A process for coating substrates using these polyurethaneurea solutions, and substrates coated by said process are also provided. The substrates coated according to the invention are preferably textile products or leather, but materials such as wood or concrete can also be coated according to the invention.

Abstract: An optical data storage comprising a thermoplastic copolycarbonate is disclosed. The copolycarbonate contains at least one unit derived from dihydroxydiphenyl ether and at least one unit derived from at least one member selected from the group consisting of 4,4?dihydroxybiphenyl and 1,1-bis-(4-hydroxyphenyl)-3,3,5-trimethylcyclohexane.

Abstract: The invention relates to a disinfectant which comprises a special combination of biocidal phenols and, where appropriate, phenol derivatives and a keratolytic. The disinfectant is particularly suitable for controlling parasitic protozoa including their persistent forms.

Abstract: A curable composition which has photochromic properties and is based on an acrylic compound which can undergo free-radical polymerization, a cured product which is obtained by thermal or photochemical curing of this curable composition on a substrate, e.g. polycarbonate glass with triplex formation (three-layered structure), and a process for the preparation of an optical material are described.

Abstract: The present invention relates to the use of selective insecticidal compositions, characterized by an effective amount of an active compound combination comprising (a) (1) at least one haloalkylnicotinic acid derivative of the formula (I) in which AA and R1A are as defined in the description, or (2) at least one phthalic acid diamide of the formula (II) in which XB, R1B, R2B, R3B, L1B, L2B and L3B are as defined in the description, or (3) at least one anthranilamide of the formula (III) in which A1C, A2C, XC, R1C, R2C, R3C, R4C, R5C, R7C, R8C and R9C are as defined in the description, and (b) at least one crop plant compatibility-improving compound from the group of compounds given in the description, in particular cloquintocet-mexyl, isoxadifen-ethyl and mefenpyr-diethyl for controlling insects and/or arachnids, and a method for controlling insects and/or arachnids using the compositions.

Abstract: This invention relates to hydroxy-tetrahydro-naphthalenylurea derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalenylurea derivatives of the present invention have an excellent activity as VR1 antagonist and are useful for the prophylaxis and treatment of diseases associated with VR1 activity, in particular for the treatment of urinary incontinence, urge urinary incontinence, overactive bladder, chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, inflammatory disorders, asthma and COPD.

Abstract: The present invention relates to novel polyether polyols containing pendant amine group and to a process for their preparation. These polyether polyols have molecular weights of from about 105 to about 35,000, and contain at least one terminal hydroxyl group and at least one pendant amine group. The process for their preparation comprises reacting a compound containing from 1 to 10 hydroxyl groups and a molecular weight of about 32 to about 15,000 with at least one epoxide which contains one or more halogen atoms, in the presence of one or more DMC catalysts, to form an intermediate polyether polyol which contains halogenated carbon atoms; then reacting this intermediate polyether polyol with an amine group containing compound having from 1 to 3 primary, secondary and/or tertiary amine groups.

Abstract: Method and system for designing experiments by selecting at least a first experiment from an experimental space using a data-driven optimizer, receiving experimentally determined data, evaluating the experimentally determined data at a mata layer module, processing the experimentally determined data at the optimizer; the processing at the optimizer being influenced by the evaluation data.

Abstract: This invention relates to certain aryl alkyl acid compounds, compositions, and methods for treating or preventing obesity and related diseases.

Abstract: Aqueous compositions comprising peroxides and polyorganopolysiloxanes useful for cleaning and disinfecting substrate surfaces.

Abstract: The present invention relates to novel substituted benzyloxy-phenylmethylamide derivatives, processes for their preparation, and their use in medicaments, especially for the prophylaxis and treatment of diseases associated with Cold Menthol Receptor 1 (CMR-1) activity, in particular for the treatment of urological diseases or disorders, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor oeractivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, and inflammatory disorders such as asthma and chronic obstructive pulmonary (or airways) disease (COPD).

Abstract: The present invention relates to products comprising a macrocylic lactone and an amidine, which products are suitable for controlling parasites, in particular ectoparasites, on animals.